Results 121 to 130 of about 2,053,097 (301)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Plot-level data of root biomass and variables derived thereof
, 2017 Root biomass was sampled to a depth of 40 cm and separated into five depth layers in the Trait-based biodiversity experiment in Jena, Germany, in 2012 and 2014. This data file contains plot-level data of root biomass (averaged over the five depth layers)
Gockele, Annette +25 more
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Вестник Кемеровского государственного университета, 2014 The paper deals with the stylistic device of “metamorphosis” and its functioning peculiarities in Selkup fairy tales and world mythology. During the analysis of folk and mythological plots the author determines the ways, reasons, character and motives of
A. V. Tereshchenko
doaj
TYPES OF PLOT. THE RETROSPECTIVE PLOT
In narratology, plot denotes the arrangement of narrative events, as distinct from the chronological sequence of events (fabula). Originating with the Russian Formalists (Propp, Shklovsky), this concept emphasizes the artistic construction of a story’s order. This article surveys plot and its varieties—chronological, non-linear, concentric, associative,
openaire +2 more sources
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Chapter 13: PLOT BY PLOT: PLOTTING URBANISM AS AN ORDINARY PROCESS OF URBANISATION
, 2023 Karaman, Ozan +3 more
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Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source