Results 131 to 140 of about 4,760,121 (354)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Who Do You Say That I Am? (Matt 16:15; Mark 8:29; Luke 9:20): Christology in the Synoptic Gospels

open access: yesReligions
This article investigates Jesus’s identity in the Synoptic Gospels by examining the Gospels’ literary features. I take a narrative approach to determine how the evangelists, in unique and shared ways, reveal to their audiences who Jesus is.
Brian Meldrum
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Renewal Features in the Structure of Dilzar's Poetic Forms

open access: yesپژوهشنامه ادبیات کردی
As an innovative Kurdish poet, Dilzar has made significant advancements in the form of his poetry, giving his work a fresh and distinct character. This study aims to explore the innovative changes that have transformed Kurdish poetry during his time ...
Sarbaz Majid Khoshnaw
doaj   +1 more source

I. L. Caragiale. Theme and Variations [PDF]

open access: yesJournal of Humanistic and Social Studies, 2010
Analyzing Caragiale’s work, a so called “unity in variety” can be noticed and his entire creation may be named after one of his sketches, Plot and variations. Since the fire on Dealul Spirii, a real story, had been given five different interpretations
Adela Drăucean
doaj  

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

The Money Plot [PDF]

open access: yes, 2008
Comprising paintings, drawings and a display of books, printed matter and other ephemera, ‘The Money Plot’, drew on autobiographical material from the artist’s own Soviet childhood as a starting point.
Gluzberg, Margarita
core  

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy