Results 81 to 90 of about 4,496,478 (332)

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

LA TRADUCTION COMPTABLE DES RISQUES EXTRÊMES [PDF]

Cet article traite de l'information relative au risque fournie dans les états financiers. Le risque peut varier selon la probabilité d'occurrence et l'estimation des dommages ; or, il semble que la comptabilité n'intègre pas toutes les dimensions du ...
Olivier Vidal, Plot Emmanuelle
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Facilitating open plot structures in story driven video games using situation generation [PDF]

, 2012
Story driven video games are rising in popularity, along with the players desire to make meaningful choice within the plot and therefore become more involved and immersed within the experience.
Brown, Gordon, King, David J.
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ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Fourier Techniques for Sound Visualization [PDF]

, 2013
Many mathematical techniques have been developed for signal analysis. The best-known -- technique is the Fourier transform, which receives a signal and outputs the frequency spec- -- trum.
Harrington, Jeremiah
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Recurrence plot statistics and the effect of embedding

, 2005
Recurrence plots provide a graphical representation of the recurrent patterns in a timeseries, the quantification of which is a relatively new field. Here we derive analytical expressions which relate the values of key statistics, notably determinism and
Bernstein, Casdagli, Church, Cutler, Davis, Eckmann, Faure, Foote, Fraser, Gao, Greenhough, Greenhough, Greenhough, Hnat, Iwanski, Kantz, Lyons, Maizel, Marwan, Marwan, Prichard, R.O. Dendy, Renyi, Roulston, S.C. Chapman, Shannon, T.K. March, Takens, Webber, Zbilut, Zbilut   +30 more
core   +2 more sources

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Calculation of Finite Size Effects on the Nucleon Mass in Unquenched QCD using Chiral Perturbation Theory

, 2004
The finite size effects on nucleon masses are calculated in relativistic chiral perturbation theory. Results are compared with two-flavor lattice results.Comment: talk at Confinement03, 5 pages latex, 3 figures. Assignment of 2 data points to incorrect
Bakeyev, T., Göckeler, M., Hemmert, T. R., Horsley, R., Irving, A. C., Khan, A. Ali, Pleiter, D., Rakow, P. E. L., Schierholz, G., Stüben, H.   +9 more
core   +3 more sources

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

DOUBLE DIFFUSION DES ENTREPRISES DANS LE RAPPORT ANNUEL : RENFORCEMENT OU CONTRADICTION ? [PDF]

Cette étude analyse la façon dont une entreprise diffuse conjointement une information obligatoire et une information volontaire à la suite d'un accident environnemental.
Emmanuelle Plot, Jonathan Maurice
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