Results 61 to 70 of about 1,581,854 (267)

Forest plots

open access: yesJournal of Physiotherapy, 2014
Forest plots are frequently used in meta-analysis to present the results graphically. Without specific knowledge of statistics, a visual assessment of heterogeneity appears to be valid and reproducible. Possible causes of heterogeneity can be explored in modified forest plots.
Verhagen, Arianne, Ferreira, ML
openaire   +3 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Nuclear fear and anxiety: Exercises in future thinking

open access: yesMemory, Mind & Media
Anxiety about nuclear war emerged after the 1945 atomic bombings of Japan and has risen and fallen over the following decades. It is grounded in future thinking shaped by narrative form and function in policy discussions and especially in film and ...
James V. Wertsch
doaj   +1 more source

Drama and satiric prose by Lutfali Hasanov

open access: yesStudia Humanitatis, 2023
The article studies drama and prose by Lutfali Hasanov who wrote and created works in Sheki literary atmosphere during the 40-70s of the 20th century and led the literary council of “Sabuhi” for a long time. The ideological relevance of the plays such as
Adishirinov Kamil Fikrat
doaj  

Phalerae from the Mound Sadovy and the Image of the ‘Tarandrus’

open access: yesВестник Волгоградского государственного университета. Серия 4. История, регионоведение, международные отношения, 2018
This paper is devoted to the content of the composition on the phalerae from the mound Sadovy and to the related issue about the existence of the ‘tarandrus’ image in the art of Eurasian nomads. L. S.
Irina P. Zasetskaya
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

СЮЖЕТНО-ПРОСТРАНСТВЕННЫЙ КОМПЛЕКС «ПЕРЕХОД ГРАНИЦЫ» В РОМАНЕ Э.М. РЕМАРКА «ТРИУМФАЛЬНАЯ АРКА»

open access: yesSovremennye Issledovaniâ Socialʹnyh Problem, 2015
В статье анализируется сюжетно-пространственный комплекс перехода границы в эмигрантском романе Э.М. Ремарка «Триумфальная арка» на материале сюжетной линии главного героя.
Alice Sergeevna Porshneva
doaj   +1 more source

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