Results 61 to 70 of about 1,581,854 (267)
Forest plots are frequently used in meta-analysis to present the results graphically. Without specific knowledge of statistics, a visual assessment of heterogeneity appears to be valid and reproducible. Possible causes of heterogeneity can be explored in modified forest plots.
Verhagen, Arianne, Ferreira, ML
openaire +3 more sources
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
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Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Nuclear fear and anxiety: Exercises in future thinking
Anxiety about nuclear war emerged after the 1945 atomic bombings of Japan and has risen and fallen over the following decades. It is grounded in future thinking shaped by narrative form and function in policy discussions and especially in film and ...
James V. Wertsch
doaj +1 more source
Drama and satiric prose by Lutfali Hasanov
The article studies drama and prose by Lutfali Hasanov who wrote and created works in Sheki literary atmosphere during the 40-70s of the 20th century and led the literary council of “Sabuhi” for a long time. The ideological relevance of the plays such as
Adishirinov Kamil Fikrat
doaj
Phalerae from the Mound Sadovy and the Image of the ‘Tarandrus’
This paper is devoted to the content of the composition on the phalerae from the mound Sadovy and to the related issue about the existence of the ‘tarandrus’ image in the art of Eurasian nomads. L. S.
Irina P. Zasetskaya
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Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
СЮЖЕТНО-ПРОСТРАНСТВЕННЫЙ КОМПЛЕКС «ПЕРЕХОД ГРАНИЦЫ» В РОМАНЕ Э.М. РЕМАРКА «ТРИУМФАЛЬНАЯ АРКА»
В статье анализируется сюжетно-пространственный комплекс перехода границы в эмигрантском романе Э.М. Ремарка «Триумфальная арка» на материале сюжетной линии главного героя.
Alice Sergeevna Porshneva
doaj +1 more source

