Results 61 to 70 of about 924,706 (320)
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu+11 more
wiley +1 more source
Seismogram Rearrangement as a Perspective Basis for Defining New Attributes
Proper regulative in earthquake risk reduction, hazard assessment, earthquake resistant design and construction of structures, should be under perpetual improvement. They are mainly the result of earthquake study and analysis of post-seismic effects.
Ranko Babić, Lidija Babić
doaj +1 more source
An Intuitive Graphical Approach to Understanding the Split-Plot Experiment [PDF]
While split-plot designs have received considerable attention in the literature over the past decade, there seems to be a general lack of intuitive understanding of the error structure of these des...
William R. Myers+2 more
openaire +2 more sources
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani+14 more
wiley +1 more source
ggmap: Spatial Visualization with ggplot2
In spatial statistics the ability to visualize data and models superimposed with their basic social landmarks and geographic context is invaluable. ggmap is a new tool which enables such visualization by combining the spatial information of static maps ...
D. Kahle, H. Wickham
semanticscholar +1 more source
ggsignif: R Package for Displaying Significance Brackets for 'ggplot2'
Research hypotheses are often concerned with the difference between two groups and statistical tests provide indicators (like p-values or Bayes factors) about the evidence for or against such differences.
C. Ahlmann-Eltze, Indrajeet Patil
semanticscholar +1 more source
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci+6 more
wiley +1 more source
Interactive and Animated Scalable Vector Graphics and R Data Displays
We describe an approach to creating interactive and animated graphical displays using R's graphics engine and Scalable Vector Graphics, an XML vocabulary for describing two-dimensional graphical displays.
Deborah Nolan, Duncan Temple Lang
doaj
A Log-Ratio Biplot Approach for Exploring Genetic Relatedness Based on Identity by State
The detection of cryptic relatedness in large population-based cohorts is of great importance in genome research. The usual approach for detecting closely related individuals is to plot allele sharing statistics, based on identity-by-state or identity-by-
Jan Graffelman+5 more
doaj +1 more source
The gap fraction (GF) of vegetative canopies is an important property related to the contained bulk of reproductive elements and woody facets within the tree crown volume.
Yunfeng Zhu+8 more
doaj +1 more source