Results 71 to 80 of about 244,053 (326)
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Deep Fluids: A Generative Network for Parameterized Fluid Simulations
, 2018 This paper presents a novel generative model to synthesize fluid simulations from a set of reduced parameters. A convolutional neural network is trained on a collection of discrete, parameterizable fluid simulation velocity fields.
Azevedo, Vinicius C. +5 more
core +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
rpanel: Simple Interactive Controls for R Functions Using the tcltk Package
Journal of Statistical Software, 2007 In a variety of settings it is extremely helpful to be able to apply R functions through buttons, sliders and other types of graphical control. This is particularly true in plotting activities where immediate communication between such controls and a ...
Adrian Bowman +3 more
doaj +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Regarding the numerical solutions of the Sharma-Tasso-Olver equation
ITM Web of Conferences, 2018 With aid of the Wolfram Mathematica package, this study investigates the solutions of a nonlinear model with strong nonlinear- ity, namely; the Sharma-Tasso-Olver equation.
Sulaiman Tukur Abdulkadir +3 more
doaj +1 more source
User's manual for EZPLOT version 5.5: A FORTRAN program for 2-dimensional graphic display of data [PDF]
EZPLOT is a computer applications program that converts data resident on a file into a plot displayed on the screen of a graphics terminal. This program generates either time history or x-y plots in response to commands entered interactively from a ...
Budd, Gerald D. +2 more
core +1 more source
IAC level "O" program development [PDF]
, 1982 The current status of the IAC development activity is summarized. The listed prototype software and documentation was delivered, and details were planned for development of the level 1 operational system.
Vos, R. G.
core +1 more source