Results 151 to 160 of about 8,480,042 (327)

Detecting small-study effects and funnel plot asymmetry in meta-analysis of survival data: A comparison of new and existing tests.

open access: yes, 2018
Small-study effects are a common threat in systematic reviews and may indicate publication bias. Their existence is often verified by visual inspection of the funnel plot.

core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

EFFECT OF PLOT SIZE ON ABOVE-GROUND CARBON STOCK ESTIMATES IN BERAU

open access: yesJurnal Belantara
In designing data collection methods to estimate carbon stocks stored above and below the forest surface, plot size is a crucial factor that needs to be considered.
Nur Fajrin, Ali Suhardiman, Yosep Ruslim
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

The Impact of Plot Size on Productivity Growth: Evidence from Southeastern China [PDF]

open access: yes
The objective of this study is to estimate the impact of plot size on productivity growth. Accordingly, we measured the size of nearly 4,000 plots using satellite images and merged them with city-level agricultural statistics for southeastern China.
Sato, Takeshi   +3 more
core   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

The Choice of Plot Size in Randomized Block Experiments1

open access: yesJournal of the American Society for Horticultural Science, 1982
Abstract Blocking of experimental units is frequently used to improve the precision of an experiment, yet many discussions of optimal plot size do not include a factor for the effect of blocking. Since there is a relationship between the choice of optimal plot size and number of plots per block, such an omission may make ...
openaire   +1 more source

Plot of test uptake on breed population size.

open access: yes, 2019
Plot and best fit line of test uptake (proportion registered dogs with result at t+4) on breed population size (mean registrations, 2000–17).
T. W. Lewis (6236339)   +1 more
core   +1 more source

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