Results 161 to 170 of about 3,502,968 (324)

Metabolic Signatures and Diagnostic Prediction Models for Coronary Artery Disease and Type 2 Diabetes Mellitus: Insights From an Exploratory Study

iNew Medicine, EarlyView.
Metabolomic & lipidomic analysis reveals metabolic overlap between CAD & T2DM, highlighting 7 key metabolites as potential biomarkers. A predictive model based on these achieves high accuracy, potentially advancing precision medicine & metabolic insights.
Zhihua Wang, Meiming Su, Ying Li, Yapei Li, Shuo Chen, Ting Peng, Hans Strijdom, Jiangang Wang, Jianping Weng, Suowen Xu   +9 more
wiley   +1 more source

Decoding temporal miRNA signatures of semen under in vitro exposure for forensic time since deposition estimation using machine learning‐driven modeling

Interdisciplinary Medicine, EarlyView.
This study develops a novel miRNA‐based framework for estimating the time since deposition of semen stains, combining small RNA sequencing with machine learning. Time‐dependent miRNA modules were identified using Mfuzz clustering and WGCNA, followed by a multi‐stage feature selection pipeline that reduced 261 candidate miRNAs to a minimal 7‐miRNA panel.
Meiming Cai, Qiong Lan, Tong Xie, Qinglin Liu, Ming Zhao, Xiaolian Wu, Xin Shi, Ruonan Shen, Yiman Wu, Chen Mao, Bin Cong, Bofeng Zhu   +11 more
wiley   +1 more source

Monitoring of Nutrients, Metabolites, IgG Titer, and Cell Densities in 10 L Bioreactors Using Raman Spectroscopy and PLS Regression Models. [PDF]

Pharmaceutics
Rubini M, Boyer J, Poulain J, Berger A, Saillard T, Louet J, Soucé M, Roussel S, Arnould S, Vergès M, Chauchard-Rios F, Chourpa I.   +11 more
europepmc   +1 more source

Complement C3 mediates adolescent social isolation‐induced hippocampal synaptic deficits and sex‐specific emotional dysfunction

Interdisciplinary Medicine, EarlyView.
Adolescent social isolation disrupts hippocampal function and exacerbates emotional symptoms, with sex‐specific patterns, as shown by human studies. In mice, social isolation decreased hippocampal synaptic density and calcium signaling, upregulated complement proteins, and activated complement‐mediated microglial synaptic phagocytosis.
Yuwan Qi, Siying Weng, Qiao Yin, Mengqi Li, Liang Shen, Enyou Qiao, Lu Gao, Yihan Wang, Yuxuan Li, Weifeng Luo, Qilin Zhang, Jing Wang, Jianfeng Feng, Qifei Cong   +13 more
wiley   +1 more source

QTN detection and candidate gene identification for improved eating and cooking quality in rice using GWAS and PLS regression analysis. [PDF]

Theor Appl Genet
Hori K, Shenton M, Mochizuki K, Suzuki K, Iijima K, Kuya N, Shu K, Ono K, Kinoshita Y, Sugimoto K, Umemoto T, Yonemaru JI, Yamasaki M, Takeuchi Y, Ebana K, Tsujii Y.   +15 more
europepmc   +1 more source

Femoral Skeletal Growth in Early Infancy Assessed by Radiofrequency Echographic Multi‐Spectrometry

Journal of Clinical Ultrasound, EarlyView.
Radiofrequency echographic multi‐spectrometry (REMS) acquisition of raw ultrasound radiofrequency signals from neonatal bone. Signals undergo preprocessing and frequency‐domain analysis to extract spectral features reflecting bone properties. A software‐guided procedure then identifies and selects standardized regions of interest (ROIs).
Serafina Perrone, Virginia Beretta, Laura Cannavò, Domenico Corica, Tommaso Aversa, Giorgia Pepe, Letteria Morabito, Maria Elisabeth Street, Malgorzata Wasniewska, Tullio Ghi, Andrea Dall'Asta   +10 more
wiley   +1 more source

Quantifying the Abundance of Alkane Moieties in Lignins with FTIR Spectroscopy and PLS Regression; Estimating Grafting Degree of Esterification. [PDF]

ChemSusChem
Heen Blindheim F, Ruwoldt J.
europepmc   +1 more source

Technostress and Technophobia: Unmasking the Impact of Coerced AI Adoption in Higher Education Institutions

Global Business and Organizational Excellence, EarlyView.
ABSTRACT This article investigates the impact of coerced AI adoption on the psychological well‐being of academic staff within higher education institutions. Data were collected from a sample of 470 faculty members randomly selected from higher education institutions in Pakistan.
Muhammad Imran Qureshi, Mehwish Iftikhar, Samer Ali Al‐shami, Shazia Qayyum   +3 more
wiley   +1 more source

Managing Spectral Intensity Variations With In‐Line Fiber‐Optic High‐Volume Noncontact Raman Probes: A Strategy Exploration

Journal of Raman Spectroscopy, EarlyView.
Robust quantification in noncontact Raman sensing requires dedicated correction of working distance dependent background effects, while laser power variations are readily stabilized using internal reference signals. Chemically relevant Raman intensity can be preserved for bulk composition measurements, under variable laser power and working distance ...
Tiril Aurora Lintvedt, Petter Vejle Andersen, Jens Petter Wold, Nils Kristian Afseth   +3 more
wiley   +1 more source

Detecting Antibiotic Resistance in Strains of Selected Gram‐Negative Bacterial Species Using Raman Spectroscopy

Journal of Raman Spectroscopy, EarlyView.
Raman spectroscopy successfully identified antibiotic‐resistant Gram‐negative strains. Resistant strains of four bacterial species were discriminated from sensitive ones with 99.1% accuracy using PLS regression. The method allows for rapid, label‐free detection of antibiotic resistance.
Fernanda Sant Ana de Siqueira e Oliveira, Adriano Moraes da Silva, Marcos Tadeu T. Pacheco, Landulfo Silveira Jr.   +3 more
wiley   +1 more source