Results 51 to 60 of about 6,722 (243)

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Hamid Dabashi, Brown Skin, White Masks

open access: yesAltre Modernità, 2012
Hamid Dabashi, Brown Skin, White Masks (London&New York, Pluto Press, 2011, pp.
Anna Vanzan
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Supervised Semantic Segmentation of Urban Area Using SAR

open access: yesRemote Sensing
Cyclical analyses of dynamic changes in urban areas are critical and necessary for policymakers and societies. Remote sensing data processing methods are currently in place to determine the distribution of built-up and sealed areas on global and ...
Joanna Pluto-Kossakowska   +1 more
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Brian Fallon. An Age of Innocence: Irish Culture 1930-1960

open access: yesABEI Journal, 1999
Brian Fallon. An Age of Innocence: Irish Culture 1930-1960. Dublin: Gill & Macmillan, 1998. 313 pp. Gerry Smyth. Decolonisation and Criticism. London: Pluto Press, 1998. 262 pp.
Marie Arndt
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Contrast Reversal and Emergent Features on Pluto

open access: yesThe Planetary Science Journal
Features that change in appearance between different NASA New Horizons images of Pluto are analyzed. Contrast reversal features (CRs) appear to transition from darker to brighter than their surroundings, more likely due to changes of imaging geometry ...
Jason D. Hofgartner   +4 more
doaj   +1 more source

Participation in residential child care in Germany

open access: yesScottish Journal of Residential Child Care, 2007
This paper sets out to examine how participation is perceived and enacted in German residential child care. Residential child care varies considerably in Germany.
Bernhard Babic, Liane Pluto
doaj   +1 more source

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