Results 61 to 70 of about 127,994 (287)

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Circumbinary Chaos: Using Pluto's Newest Moon to Constrain the Masses of Nix & Hydra

, 2012
The Pluto system provides a unique local laboratory for the study of binaries with multiple low mass companions. In this paper, we study the orbital stability of P4, the most recently discovered moon in the Pluto system.
Andrew N. Youdin, Buie, Buie, Canup, Chambers, Dobrovolskis, Dvorak, Fabrycky, Holman, Johansen, Johansen, Kaitlin M. Kratter, Kenyon, Kenyon, Lambrechts, Lissauer, Lithwick, Lithwick, Mudryk, Nesvorný, Nesvorný, Parker, Peale, Ragozzine, Scott J. Kenyon, Shariff, Showalter, Stern, Stern, Tholen, Youdin, Youdin, Youdin, Youdin, Youdin, Young   +35 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

On the escape of CH4 from Pluto's atmosphere

, 2015
We adapted a multi-species escape model, developed for close-in extrasolar planets, to calculate the escape rates of CH4 and N2 from Pluto. In the absence of escape, CH4 should overtake N2 as the dominant species below the exobase.
Erwin, J. T., Koskinen, T. T., Yelle, R. V.   +2 more
core   +1 more source

Radiation hydrodynamics integrated in the code PLUTO [PDF]

, 2013
The transport of energy through radiation is very important in many astrophysical phenomena. In dynamical problems the time-dependent equations of radiation hydrodynamics have to be solved.
Kley, Wilhelm, Kolb, Stefan M., Mignone, Andrea, Stute, Matthias   +3 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Timing and Abundance of Clathrate Formation Control Ocean Evolution in Outer Solar System Bodies: Challenges of Maintaining a Thick Ocean within Pluto

The Planetary Science Journal, 2023
Clathrate hydrates may represent a sizable fraction of material within the icy shells of Kuiper Belt objects and icy moons. They influence the chemical and thermal evolution of subsurface oceans by locking volatiles into the ice shell and by providing ...
Samuel W. Courville, Julie C. Castillo-Rogez, Mohit Melwani Daswani, Elodie Gloesener, Mathieu Choukroun, Joseph G. O’Rourke   +5 more
doaj   +1 more source

This Is Not a Myeloproliferative Neoplasm…

Pediatric Blood &Cancer, EarlyView.
Stephanie Juané Kennedy
wiley   +1 more source