Results 81 to 90 of about 49,031 (291)
Participation in residential child care in Germany
Scottish Journal of Residential Child Care, 2007 This paper sets out to examine how participation is perceived and enacted in German residential child care. Residential child care varies considerably in Germany.
Bernhard Babic, Liane Pluto
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
This lithograph shows the clearest view yet of the distant planet Pluto and its moon, Charon, as revealed by NASA's Hubble Space Telescope. The images are accompanied by a brief description and history, some statistical facts, and important dates in the ...
core +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
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, 2014 I juli 2015 når NASA-rymdsonden New Horizons till solsystemets mest kända dvärgplanet Pluto.
Wahlberg Jansson, Karl
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Kiladze Caldera: A Possible Cryovolcano on Pluto
The Planetary Science JournalIn contrast with regional primarily methane composition, Kiladze and its surroundings exhibit a water-ice spectral signature that carries an ammoniated compound, similar to two other cryovolcanic sites on Pluto.
A. Emran +4 more
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Brian Fallon. An Age of Innocence: Irish Culture 1930-1960
ABEI Journal, 1999 Brian Fallon. An Age of Innocence: Irish Culture 1930-1960. Dublin: Gill & Macmillan, 1998. 313 pp. Gerry Smyth. Decolonisation and Criticism. London: Pluto Press, 1998. 262 pp.
Marie Arndt
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source