Results 91 to 100 of about 49,031 (291)
Results obtained with the PLUTO detector at PETRA are presented. Multihadron final states have been analysed with respect to clustering, energy‐energy correlations and transverse momenta in jets.
PLUTO Collaboration, Hepp, V.
core
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Supervised Semantic Segmentation of Urban Area Using SAR
Cyclical analyses of dynamic changes in urban areas are critical and necessary for policymakers and societies. Remote sensing data processing methods are currently in place to determine the distribution of built-up and sealed areas on global and ...
Joanna Pluto-Kossakowska +1 more
doaj +1 more source
Presentation: The Amazing Mission to Pluto: Three Billion Miles Away and We Made It! [PDF]
More than three billion miles away and ten years in the making, the New Horizons Mission to Pluto brings invaluable information from the outer reaches of our solar system.
Stern, Alan +1 more
core +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Contrast Reversal and Emergent Features on Pluto
Features that change in appearance between different NASA New Horizons images of Pluto are analyzed. Contrast reversal features (CRs) appear to transition from darker to brighter than their surroundings, more likely due to changes of imaging geometry ...
Jason D. Hofgartner +4 more
doaj +1 more source
A Rose By Any Other Name: The Peculiar Case of Pluto [PDF]
These are the teaching notes for a case study in which students examine the dilemma of deciding whether Pluto is a planet. The storyline follows scientific data, historical events, and personal stories regarding the status of Pluto as the ninth planet. A
Teresa Schulz
core
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Postcard of the Famous Pluto Spring located in French Lick, Indiana.Postcard of the Famous Pluto Spring in French Lick ...
core +1 more source
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source

