Results 61 to 70 of about 971,010 (279)

PM-produced Tr-OxPLs increase endothelial permeability.

, 2018
(A) Purified Tr-OxPLs were added to EC monolayers at indicated concentrations and TER was determined over time for lyso-PC (left panel), POVPC (middle panel) and PGPC (right panel). Next, cells were treated with sub-maximal lower (B) and higher (C) doses
Alok Shah (5954273), Anna A. Birukova (333901), Angelo Meliton (585051), Tomomi Ohmura (5954276), Pratap Karki (558676), Nicolene Sarich (627041), Konstantin G. Birukov (333911), Yufeng Tian (343868)   +7 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Hydrodynamic Simulations of a 2MW Offshore Solar Farm with Floating Breakwater Protection

Energies
Following successful applications in inland water bodies, floating photovoltaics (FPV) developers are now targeting offshore sites. This advancement requires numerical tools that can quantify the hydrodynamic performance of large-scale FPV farms.
Tim Bunnik, Naman Baderiya, Joep van der Zanden   +2 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Full Densification in PM Steels Through Liquid Phase Sintering and HIP Approach

, 2020
High-density powder metallurgy (PM) components are required for high-performance applications. Liquid phase sintering (LPS) is one such method to improve the densification, especially the master alloy route is preferred due to the flexibility in ...
Nyborg, Lars, Vattur Sundaram, Maheswaran, Castro, Francisco, Hryha, Eduard, Berg, Siguard, Surreddi, Kumar Babu, Veiga, Angela   +6 more
core   +3 more sources

Experimental optimisation of the man overboard manoeuvre

Applied Ocean Research
In maritime operations, the safety of crew and passengers is paramount, making the man overboard manoeuvre a critical emergency procedure for all vessels. Among the different ways to perform this manoeuvre, the Williamson turn is used to come back on its
Bas J. de Kruif, Bülent Düz, Victor Ferrari   +2 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Development Of Decision Model For Maintenance Analysis Of Non-Repairable Component By Considering The External Factor [TS192. R821 2007 f rb]. [PDF]

, 2007
Penyelenggaraan pencegahan (Preventive Maintenance – PM) merupakan salah satu strategi yang digunakan untuk mengurangkan masalah kerosakan mesin yang berlaku secara tiba-tiba. Preventive Maintenance (PM) is one of the strategies that can be applied to
Rosmaini, Ahmad
core   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source