Results 101 to 110 of about 15,020 (275)
, 2019 The tumor suppressor p53 is a key mediator of cellular stress and DNA damage response cascades and is activated after exposure to ionizing radiation. Amplifying wild-type p53 expression by targeting negative regulators such as MDM2 in combination with ...
Marika Nestor (555081) +4 more
core +1 more source
Microstructure, Defects, and Fatigue Response of High‐Strength Tool Steels
steel research international, EarlyView.The martensitic tool steel family is designed for use in various working environments where they are subjected to repeatedly high mechanical loads. Despite the continuous upgrade of material´s microstructures through compositional development or processing techniques, defects remain a critical factor for the tool performance by leading to fatigue ...
Katerina Chantziara +3 more
wiley +1 more source
, 2017 To obtain a thorough knowledge of PM2. 5 chemical composition and its impact on aerosol optical properties across China, existing field studies conducted after the year 2000 are reviewed and summarized in terms of geographical, interannual and ...
Zhang,LM(Zhang,Leiming) +4 more
core +1 more source
Journal of Synchrotron Radiation, EarlyView.The performance evaluation and improvement of an X‐ray ionization beam position monitor for soft X‐ray free‐electron lasers is presented.An X‐ray ionization beam position monitor (XIBPM) has been developed and evaluated for beam position diagnostics at a soft X‐ray free‐electron laser (FEL).
SunMin Hwang +9 more
wiley +1 more source
Integrative Zoology, EarlyView.Brain size may be influenced by the cognitive demands of sociality (social brain hypothesis). We used microCT to compare CNS and brain volumes in social versus solitary huntsman and crab spiders. Social huntsman spiders had larger arcuate and mushroom bodies, while social crab spiders had larger visual neuropils.
Vanessa Penna‐Gonçalves +6 more
wiley +1 more source
Movement Disorders Clinical Practice, EarlyView.
Bruno Antunes Contrucci +10 more
wiley +1 more source
Andrology, EarlyView.ABSTRACT Background Oligoasthenoteratozoospermia (OAT), characterized by reduced sperm count, impaired motility, and abnormal morphology, is a major cause of male infertility with substantial genetic heterogeneity. However, the underlying genetic etiology remains unresolved in a large proportion of affected individuals.
Jianteng Zhou +8 more
wiley +1 more source
Acta Ophthalmologica, EarlyView.Abstract Purpose To determine the molecular cause of the two epithelial recurrent erosion dystrophies, Dystrophia Smolandiensis and Dystrophia Helsinglandica, and to identify phenotypic differences between the two conditions. Methods DNA samples and clinical data from structured interview records were obtained from the Swedish families in which ...
Karl De Geer +5 more
wiley +1 more source
Figure S4 from The MDM2/MDMX-p53 Antagonist PM2 Radiosensitizes Wild-Type p53 Tumors
, 2018 Supplemental Figure 4: Effects of PM2 treatment in UM-SCC-74B (wt p53) and BON (mutant p53) xenografts. A) Ex vivo immunohistochemistry images of p53 expression in control or PM2-treated UM-SCC-74B xenografts taken at the last treatment day.
Marika Nestor (555081) +5 more
core +1 more source
British Journal of Haematology, EarlyView.Targeted next‐generation sequencing combined with a structured interpretative framework integrating gene–disease validity, population data, computational predictions, ACMG criteria and structural modelling enabled prioritisation of rare variants in idiopathic erythrocytosis, highlighting the genetic heterogeneity and biological complexity underlying ...
Alessandra Giannella +21 more
wiley +1 more source