Results 121 to 130 of about 16,675 (221)
The Same Homozygous Pathogenic Variant in CHAT Underlies Lethal Fetal Akinesia Syndrome in Three Xhosa South African Fetuses. [PDF]
Prenatal Diagnosis, Volume 46, Issue 10, Page 1655-1659, September 2026.
Ramini J +6 more
europepmc +2 more sources
The tumor suppressor p53 is a key mediator of cellular stress and DNA damage response cascades and is activated after exposure to ionizing radiation. Amplifying wild-type p53 expression by targeting negative regulators such as MDM2 in combination with ...
Marika Nestor (555081) +4 more
core +1 more source
The RE4Al13Pt9 series has been extended to RE = Y, La‐Nd, Sm, Gd‐Dy. The compounds have been investigated by X‐ray diffraction and magnetic susceptibility measurements. Of the RE4Al13Pt9 series, the RE = Ce, Pr, and Eu representatives were previously reported. In this work we extend the series to RE = Y, La‐Nd, Sm, Gd‐Dy.
Stefan Engel +3 more
wiley +1 more source
Yb[N(CN)2]2Cl·5H2O: The First Mixed‐Anionic Dicyanamide‐Based Chloride Hydrate
The title compound Yb[N(CN)2]2Cl·5H2O crystallizes in the triclinic space group P 1¯$\overline{1}$ with the lattice parameters as a = 926.57(5) pm, b = 1111.65(6) pm, c = 1252.08(7) pm, α = 97.239(2)°, β = 94.641(2)°, γ = 103.038(2)° for Z = 4. Partial metathesis reactions of ytterbium trichloride hexahydrate (YbCl3·6H2O) with silver(I) dicyanamide (Ag[
Ralf J. C. Locke +2 more
wiley +1 more source
Replication of bacteriophage PM2 deoxyribonucleic acid: A closed circular double-stranded molecule
Shortly after infection with bacteriophage PM2, host DNA synthesis is inhibited while synthesis of the supercoiled viral DNA begins at a low rate. This rate increases at about ten minutes after infection to reach a value that is thereafter maintained ...
Espejo, Romilio T. +2 more
core
Scalable Emitter Photonic Integrated Circuits on an Open‐Access Indium Phosphide Foundry
An open‐access indium phosphide platform with high‐speed 80 GBaud modulators delivers versatile emitter PICs. By showcasing a widely tunable optical frequency comb generator, a 672 MHz record low‐repetition‐rate mode‐locked extended cavity mode locked laser, and monolithic InP tunable laser with a narrow linewidth of 8.2 kHz, this work presents a ...
Durvasa Y. Gupta +4 more
wiley +1 more source
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
Prominent Movement Disorders in RNU2‐2‐Related Spliceosomopathy
ABSTRACT Pediatric movement disorders often overlap with neurodevelopmental diseases, suggesting shared molecular mechanisms. Variants in small nuclear RNA (snRNA) genes encoding spliceosome components have recently been associated with neurodevelopmental disorders, termed “RNUopathies.” We analyzed genome sequencing data from 14 patients with ...
Magdalena Krygier +6 more
wiley +1 more source
Hemoglobin's α‐Helix‐to‐β‐Sheet Transition Enables Targeted mRNA Delivery to the Lung
Acidic heating converts hemoglobin into β‐sheet‐rich fibrils with positively charged surfaces. These hemoglobin fibrils electrostatically complex IL‐11 scFv mRNA, selectively bind circulating platelets, and hitchhike to the lung, where they are enriched in fibroblasts.
Xihua Liu +11 more
wiley +1 more source
Virulence and diversity of Blumeria graminis f. sp. tritici populations in Henan Province, China
Wheat powdery mildew, caused by Blumeria graminis f. sp. tritici (Bgt), is an important disease affecting wheat production in Henan Province, China. In this study, 915 isolates from 2011 to 2020 were obtained from 14 cities/counties, virulence assessment
Junmei Wang +13 more
doaj +1 more source

