Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley +1 more source
Early disease stages showed limited cortical atrophy and enrichment of synaptic and calcium signaling pathways, whereas advanced stages demonstrated widespread cortical degeneration associated with immune activation and extracellular matrix remodeling.
Yi Ji +6 more
wiley +1 more source
Design Analysis for Controlling Spray Particle Size of Ultrasonic Nozzles Using Piezoelectric Ceramic Vibrators. [PDF]
Lee SH +4 more
europepmc +1 more source
Ideal : relatório de estágio - Ideal Artes Gráficas
Estágio realizado na Tipografia Ideal de Guimarães Luís Caldas & CoutinhoRelatório do Estágio Curricular da LGEI 2005 ...
Coutinho, Carlos Duarte Lopes
core
Next‐Generation Paleopathology: Using Commercial AI in Bioarchaeological Diagnosis
ABSTRACT Artificial intelligence encompasses computational systems capable of performing cognitive functions such as learning, reasoning, and problem‐solving. Within this domain, generative AI and large language models such as ChatGPT, Gemini, and Copilot have shown significant potential in clinical diagnostics.
Jessica Mongillo +4 more
wiley +1 more source
Modeling, simulation, and optimization behavior of pharmaceutical compound removal from water in SR-AOPs technique for wastewater treatment. [PDF]
Kriaa K +7 more
europepmc +1 more source
When Fat Goes Astray: Your Liver and Pancreas Get Into Trouble
Metabolic dysfunction‐associated steatotic liver disease (MASLD) and intrapancreatic fat deposition (IPFD) are both common manifestations of ectopic fat accumulation. Although they share multiple risk factors, they also show notable differences in pathological features, standardization of diagnosis, and research maturity.
Yuying Chen +5 more
wiley +1 more source
Flower-like CoFe-LDH Activated Peroxymonosulfate for Tetracycline Degradation: Efficiency and Mechanism. [PDF]
Luo Y, Zhou Y, Xu T, Su R, Ma X, Yan W.
europepmc +1 more source
Actuation Strategies for Underwater Jet‐Propelled Soft Robots
ABSTRACT This review article examines jet‐propulsion mechanisms in underwater soft robotic systems, focusing exclusively on physically fabricated and experimentally validated robots. Covering research published from 2013 to 2025, this study classifies and evaluates jet‐propulsion robots based on their actuation mechanisms.
Angel Kitone +3 more
wiley +1 more source
Mn<sub>3</sub>O<sub>4</sub>/biochar catalyst for enhanced PMS activation and antibiotic degradation <i>via</i> radical and non-radical pathways. [PDF]
Aadil M +8 more
europepmc +1 more source

