Results 21 to 30 of about 133,257 (324)

Reconfigurable Smart Contracts for Renewable Energy Exchange with Re-Use of Verification Rules

Applied Sciences, 2022
Smart contracts constitute the foundation for blockchain distributed applications. These constructs enable transactions in trustless environments using consensus algorithms and software-controlled verification rules.
Tomasz Górski
doaj   +1 more source

Exploiting double exchange Diels-Alder cycloadditions for immobilization of peptide nucleic acids on gold nanoparticles [PDF]

, 2020
The generation of PNA-decorated gold nanoparticles (AuNPs) has revealed to be more difficult as compared to the generation of DNA-functionalized ones. The less polar nature of this artificial nucleic acid system and the associated tendency of the neutral
Cadoni, Enrico, Madder, Annemieke, Mancin, Fabrizio, Manicardi, Alex, Rosa-Gastaldo, Daniele   +4 more
core   +2 more sources

Simple representation of physiological regulations in a model of lactating female: application to the dairy goat

Animal, 2008
A dynamic model of the lactating dairy goat, combining a minimum of mechanistic representations of homeorhetic regulations and a long-term approach, was developed.
L. Puillet, O. Martin, M. Tichit, D. Sauvant   +3 more
doaj   +1 more source

Continuous Delivery of Blockchain Distributed Applications

Sensors, 2021
Ensuring a production-ready state of the application under development is the imminent feature of the Continuous Delivery (CD) approach. In a blockchain network, nodes communicate and store data in a distributed manner.
Tomasz Górski
doaj   +1 more source

Antisense PNA accumulates in Escherichia coli and mediates a long post-antibiotic effect [PDF]

, 2007
Antisense agents that target growth-essential genes display surprisingly potent bactericidal properties. In particular, peptide nucleic acid (PNA) and phosphorodiamidate morpholino oligomers linked to cationic carrier peptides are effective in time kill ...
Behmanesh, Mehrdad, Dryselius, Rikard, Faridani, Omid R, Ganyu, Anita, Goh, Shan, Good, Liam, Klok, Erik Jan, Nikravesh, Abbas, Sadeghizadeh, Majid, Zain, Rula   +9 more
core   +2 more sources

Is there a relationship between the quality of surface watercourses associated with rural landscapes and the level and type of anthropization in the zone of influence?

Ecología Austral, 2023
The study of the environmental quality of the largest rivers such as the Paraná, is a challenge for the different disciplines of environmental sciences.
M. Leticia Peluso, Pablo M. Demetrio, Constanza Bernasconi, Natalia Aprigliano, Gabriela Riviello López, Mariana Abelando, Federico Rimoldi   +6 more
doaj   +1 more source

Nucleobase‐caged peptide nucleic acids: PNA/PNA duplex destabilization and light‐triggered PNA/PNA recognition

Journal of Peptide Science, 2013
The 2‐(o‐nitrophenyl)‐propyl (NPP) group is used as caging group to mask the nucleobases adenine and cytosine in N‐(2‐aminoethyl)glycine peptide nucleic acids (aeg‐PNA). The adeninyl and cytosinyl nucleo amino acid building blocks Fmoc‐aNPP‐aeg‐OH and Fmoc‐cNPP‐aeg‐OH were synthesized and incorporated into PNA sequences by Fmoc solid phase synthesis ...
Guha, Samit, Graf, Julia, Goericke, Bjoern, Diederichsen, Ulf   +3 more
openaire   +3 more sources

Peptide Nucleic Acids and Gene Editing: Perspectives on Structure and Repair

Molecules, 2020
Unusual nucleic acid structures are salient triggers of endogenous repair and can occur in sequence-specific contexts. Peptide nucleic acids (PNAs) rely on these principles to achieve non-enzymatic gene editing.
Nicholas G. Economos, Stanley Oyaghire, Elias Quijano, Adele S. Ricciardi, W. Mark Saltzman, Peter M. Glazer   +5 more
doaj   +1 more source

Acid-base and lipophilic properties of peptide nucleic acid derivatives

Journal of Pharmaceutical Analysis, 2021
The first combined experimental and theoretical study on the ionization and lipophilic properties of peptide nucleic acid (PNA) derivatives, including eleven PNA monomers and two PNA decamers, is described.
Pramod Thakare, Francesca Vasile, Maura Vallaro, Sonja Visentin, Giulia Caron, Emanuela Licandro, Silvia Cauteruccio   +6 more
doaj   +1 more source

Identifying remote sources of interannual variability for summer precipitation over Nordic European countries tied to global teleconnection wave patterns

Tellus: Series A, Dynamic Meteorology and Oceanography, 2020
We show evidence that tropical atmospheric variability over the central tropical Pacific modulates the circulation over the western Arctic and the North Atlantic-European sector, impacting the summer precipitation especially over Nordic European ...
Ramón Fuentes-Franco, Torben Koenigk
doaj   +1 more source