Continuing effectiveness of serogroup A meningococcal conjugate vaccine, Chad, 2013. [PDF]
In 2011, vaccination with a serogroup A meningococcal polysaccharide conjugate vaccine was implemented in 3 of 23 regions in Chad. Cases of meningitis declined dramatically in vaccinated areas, but an epidemic continued in the rest of Chad.
Greenwood, Brian M +35 more
core +1 more source
Death or survival from invasive pneumococcal disease in Scotland: associations with serogroups and multilocus sequence types [PDF]
We describe associations between death from invasive pneumococcal disease (IPD) and particular serogroups and sequence types (STs) determined by multilocus sequence typing (MLST) using data from Scotland.
Mitchell, Tim J +52 more
core +1 more source
In-vitro and in-vivo expression analysis of pneumococcal vaccine candidates: pilus-1 components [PDF]
Streptococcus pneumoniae (S. pneumoniae) is a Gram-positive commensal of the nasopharyngeal tract of both children and healthy adults. However, S. pneumoniae is also a leading cause of morbidity and mortality worldwide, being responsible for non-invasive
De Angelis, Gabriella
core +1 more source
The New Era of Pneumococcal Vaccination in Adults: What Is Next?
Streptococcus pneumoniae remains the leading cause of community-acquired pneumonia in adults and bacterial meningitis in children worldwide. In addition to pneumonia, invasive pneumococcal diseases (IPDs), such as bacteremia and meningitis, pose a ...
Lale Ozisik
doaj +1 more source
Pneumococcal conjugate vaccines—a European perspective
Streptococcus pneumoniae is a leading cause of bacterial pneumonia, meningitis, and acute otitis media in children and adults worldwide. In the age group of < 2 years the incidence of invasive pneumococcal disease ranges from approximately 14 cases per 100,000 in Germany and the Netherlands and more than 90 per 100,000 children in Spain.
openaire +2 more sources
Recent Advances in Pneumococcal Conjugate Vaccines: A 13-Valent Pneumococcal Conjugate Vaccine
Streptococcus pneumoniae (pneumococcus) is an important cause of serious infectious diseases, leading to death among children all over the world. The 7-valent pneumococcal conjugate vaccine (PCV7), which was introduced in 2000 to prevent pneumococcal infections, was included in the Childhood National Immunization Program of Turkey in November 2008 and ...
openaire +2 more sources
Background Vaccination of infants with pneumococcal conjugate vaccines is recommended by the World Health Organization. Evidence is mixed regarding the differences in immunogenicity and efficacy of the different pneumococcal vaccines.
Shuo Feng +13 more
doaj +1 more source
Antibody responses to nasopharyngeal carriage of Streptococcus pneumoniae in adults: A longitudinal household study [PDF]
Background. Natural immunity to Streptococcus pneumoniae is thought to be induced by exposure to S. pneumoniae or cross-reactive antigens. No longitudinal studies of carriage of and immune responses to S.
Hussain, M +12 more
core
We applied the indirect cohort method to estimate effectiveness of 10-valent pneumococcal conjugate vaccine (PCV10) among young children in Brazil. Cases of invasive pneumococcal disease (IPD), i.e., Streptococcus pneumoniae, detected in normally sterile
core
Neutrophils induce effective antibody responses to the pneumococcal conjugate vaccine by inhibiting T regulatory cells. [PDF]
Tchalla EYI +7 more
europepmc +1 more source

