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Effect of Pneumococcal Conjugate Vaccine on Pneumococcal Meningitis [PDF]
New England Journal of Medicine, 2009 Invasive pneumococcal disease declined among children and adults after the introduction of the pediatric heptavalent pneumococcal conjugate vaccine (PCV7) in 2000, but its effect on pneumococcal meningitis is unclear.We examined trends in pneumococcal meningitis from 1998 through 2005 using active, population-based surveillance data from eight sites in
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Pneumococcal conjugate vaccines
Immunology Letters, 1991We have prepared conjugates of pneumococcal type 4 polysaccharides (PS4) or oligosaccharides to tetanus toxoid using the carbodiimide method. The use of a spacer, 6-aminohexanoic acid, resulted in higher incorporation of carrier protein. Conjugates contained up to 10% free polysaccharide, but no free protein.
C C, Peeters +6 more
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Pneumococcal conjugate vaccine
Current Opinion in Pediatrics, 2001Pneumococcal infections account for a significant proportion of bacterial infections in infants and children. The growing threat from pneumococci resistant to penicillin and other antimicrobials has led to increased pressure for the development of an effective vaccine.
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Conjugated Heptavalent Pneumococcal Vaccine
The Annals of Pharmacotherapy, 2002OBJECTIVE: To review the immunogenicity, efficacy, and safety of the heptavalent conjugated pneumococcal vaccine (PCV7). DATA SOURCES: A MEDLINE search (1993–August 2001) of research limited to humans published in the English language ...
Vinita B, Pai +2 more
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