Results 31 to 40 of about 35,299 (221)
Invasive pneumococcal disease is a relevant public health problem in Brazil, especially among children and the elderly. In July/2010 a 10-valent pneumococcal conjugate vaccine was introduced to the immunization schedule of Brazilian children under two ...
Carolina Regis Leite +5 more
doaj +1 more source
HIV-patients have excess of pneumococcal infection. We immunized 40 HIV-patients twice with pneumococcal conjugate vaccine (Prevnar, Pfizer) +/− a TLR9 agonist (CPG 7909).
Rasmus Offersen +5 more
doaj +1 more source
Molecular dynamics of the host response to Streptococcus pneumoniae pneumonia in baboons
Using an established, clinically relevant nonhuman primate model of S. pneumoniae pneumonia, this study aims to identify novel potential molecular diagnostic and therapeutic targets using peripheral blood bulk transcriptomic, unbiased proteomic, and cytokine measurements. The constructed models were highly accurate in classifying bacterial pneumonia in
Bryan D. Kraft +18 more
wiley +1 more source
Otitis media (OM) is a middle ear infection driven by chronic inflammation, leading to tissue damage and complications such as cholesteatoma. Flavonoids, a class of polyphenols with anti‐inflammatory properties, suppress key inflammatory mediators, reducing neutrophilic infiltration and mucosal thickening. These findings suggest flavonoids as potential
Madiha Ajaz +3 more
wiley +1 more source
Diseases caused by Streptococcus pneumoniae, as well as antibiotic resistance of its serotypes, are the leading cause of death amongst children worldwide.
V. P. Trukhin +5 more
doaj +1 more source
Production and efficacy of a low-cost recombinant pneumococcal protein polysaccharide conjugate vaccine. [PDF]
Streptococcus pneumoniae is the leading cause of bacterial pneumonia. Although this is a vaccine preventable disease, S. pneumoniae still causes over 1 million deaths per year, mainly in children under the age of five.
Abouelhadid, Sherif +7 more
core +3 more sources
ABSTRACT Background COVAX was designed to support the discovery, development, and distribution of COVID‐19 vaccines globally, at scale and pace. This article examines how COVAX promoted vaccine equity and what lessons can be learnt. Methods Informed by a scoping review of lessons learnt from GHPs, we reviewed 109 documents related to COVAX and other ...
Charnele Nunes +3 more
wiley +1 more source
Background There is great interest in the use of reduced dosing schedules for pneumococcal conjugate vaccines, a strategy premised on maintaining an acceptable level of protection against disease and carriage of the organism.
Alan Yang, Francisco Cai, Marc Lipsitch
doaj +1 more source
Abstract HPV vaccination reduces the risk of developing HPV‐attributable cancers, including cervical cancer. However, an attenuation of HPV vaccine impact after the implementation of HPV vaccination may occur through clinical unmasking. Clinical unmasking is a distinct and complex phenomenon that arises in the absence of clinical interventions ...
Joseph E. Tota +8 more
wiley +1 more source
Reply letter to “response to article by Johnna Perdrizet et al.” by Gomez and colleagues
This communication seeks to address the questions and criticisms issued by Gomez and colleagues in their letter on our original study “Cost-effectiveness analysis of replacing the 10-valent pneumococcal conjugate vaccine (PCV10) with the 13-valent ...
Johnna Perdrizet +6 more
doaj +1 more source

