Results 41 to 50 of about 15,396 (182)
Introduction Pneumococcal disease is a serious global public health concern. The primary causative agent of severe illnesses such as pneumonia, meningitis, acute otitis media, and bacteremia is the pneumococcus bacterium.
Tadesse Tarik Tamir +4 more
doaj +1 more source
Personalized Cancer Vaccines in the Clinical Trial Pipeline
ABSTRACT Aim To present an overview of personalized cancer vaccines currently undergoing clinical development, aiming to enhance awareness and promote collaboration among academic, commercial researchers, and non‐profit communities. Methods A dataset of 78 clinical trials for personalized cancer vaccines was generated using ClinicalTrials.gov database ...
Liudmila Iamukova, Elena Alferova
wiley +1 more source
Invasive pneumococcal disease in relation to vaccine type serotypes
Since 1983 the world has been introduced to four vaccines combating disease caused by Streptococcus pneumoniae bacteria. However, despite vaccination programs disease caused by S.
Paeton L. Wantuch, Fikri Y. Avci
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The 7-valent pneumococcal conjugate vaccine (PCV7) is currently being introduced in the vaccine schedule of over 90 countries around the world. After the introduction of the PCV7 vaccine in the United States, a reduction of more than 90% of invasive ...
Oana Falup-Pecurariu
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This review provides a detailed record of recent advances in the field of determining protein conformation and orientation on various interfaces using sum frequency generation vibrational spectroscopy. We delve deep into how the addition of the Hamiltonian spectral matching formalism, isotope labeling, and Molecular Dynamics simulations has allowed us ...
Zahra Asif Gandhi +2 more
wiley +1 more source
Introduction Africa harbours a high burden of pneumococcal disease, with associated high mortality rates. Despite 34 countries introducing the pneumococcal conjugate vaccine, which reduces the risk of pneumococcal carriage (a prerequisite for disease) of
Neil French +7 more
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We report on a patient homozygous for a novel autosomal recessive loss‐of‐function CARD11 variant, with susceptibility to live attenuated virus (LAV) vaccines and impaired clearance of multiple naturally acquired respiratory viral infections. Inborn errors of immunity affecting the CARD11‐BCL10‐MALT1 (CBM) complex should be considered in individuals ...
Hamish Anderson +12 more
wiley +1 more source
We used whole-genome sequencing to characterize 199 nonvaccine serotype 35B pneumococcal strains that caused invasive pneumococcal disease (IPD) in the United States during 2015–2016 and related these findings to previous serotype 35B IPD data obtained ...
Sopio Chochua +6 more
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ABSTRACT Background and Aims Meningitis remains a global health challenge, characterized by substantial regional and etiologic disparities. This study aimed to analyze recent trends, forecast future burden, and examine the influence of development status on meningitis outcomes.
Mehdi Azizmohammad Looha +4 more
wiley +1 more source

