Results 31 to 40 of about 15,396 (182)

Human monoclonal antibodies isolated from a primary pneumococcal conjugate Vaccinee demonstrates the expansion of an antigen-driven Hypermutated memory B cell response

BMC Infectious Diseases, 2018
Background Community-acquired pneumonia is a leading infectious cause of hospitalization. A few vaccines exist to prevent pneumococcal disease in adults, including a pneumococcal polysaccharide unconjugated vaccine and a protein conjugated polysaccharide
Zhifeng Chen, Kara S. Cox, Aimin Tang, Jeanette Roman, Malorie Fink, Robin M. Kaufhold, Liming Guan, Andy Xie, Melissa A. Boddicker, Debra Mcguinness, Xiao Xiao, Hualin Li, Julie M. Skinner, Thorsten Verch, Mary Retzlaff, Kalpit A. Vora   +15 more
doaj   +1 more source

Efficacy and effectiveness of extended-valency pneumococcal conjugate vaccines [PDF]

Korean Journal of Pediatrics, 2014
The 7-valent pneumococcal protein conjugate vaccine (PCV7) has been shown to be highly efficacious against invasive pneumococcal diseases and effective against pneumonia and in reducing otitis media. The introduction of PCV7 has resulted in major changes
Hyunju Lee, Eun Hwa Choi, Hoan Jong Lee
doaj   +1 more source

A Protocol of National Mixed‐Methods Assessment of Childhood and Maternal Immunization

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background and Aims Accurate measurement of routine immunization coverage is essential for detecting immunity gaps, guiding programmatic responses, and supporting equitable vaccine delivery. Iran's Expanded Programme on Immunization has achieved high coverage, but administrative estimates can mask some disparities.
Seyed Aria Nejadghaderi, Paria Dehesh, Mehran Nakhaeizadeh, Mohammadreza Rajabalipour, Faeze Tahrudi, Naser Nasiri, Seyed Mohsen Zahraei, Hamid Sharifi, AliAkbar Haghdoost   +8 more
wiley   +1 more source

INTERNATIONAL EXPERIENCE WITH 7-VALENT PNEUMOCOCCAL CONJUGATE VACCINE

Педиатрическая фармакология, 2009
The article is devoted to one of the serious problems of the today's medicine — pneumococcal infection. The authors show its importance for public health in terms of its influence upon infant and child mortality and in validization.
David G. McIntosh
doaj   +2 more sources

Outbreak of Serotype 1 Invasive Pneumococcal Disease, Kibera Urban Informal Settlement, Nairobi, Kenya, 2023

Emerging Infectious Diseases
Use of 10-valent pneumococcal conjugate vaccine in Kenya has led to substantial reductions in vaccine-type pneumococcal carriage and invasive pneumococcal disease.
Terry Komo, Patrick K. Munywoki, Maria da Gloria Carvalho, Joshua Auko, Alice Ouma, Allan Audi, George O. Agogo, Daniel Omondi, Arthur Odoyo, Herine Odiembo, Newton Wamola, Mike Osita, Clayton Onyango, Naomi Lucchi, Peninah Munyua, Amy Herman-Roloff, Shanda Larson, Sopio Chochua, Fabiana C. Pimenta, Godfrey Bigogo, Jennifer R. Verani   +20 more
doaj   +1 more source

The 13-Valent Pneumococcal Conjugate Vaccine Elicits Serological Response and Lasting Protection in Selected Patients With Primary Humoral Immunodeficiency

Frontiers in Immunology, 2021
BackgroundPatients with primary humoral immunodeficiency are more prone to invasive as well as recurrent pneumococcal infections. Therefore, anti-pneumococcal vaccination including the 13-valent conjugate vaccine is recommended. Nevertheless, to date, no
Ailsa Robbins, Ailsa Robbins, Mathilde Bahuaud, Maxime Hentzien, Quentin Maestraggi, Coralie Barbe, Delphine Giusti, Delphine Giusti, Richard Le Naour, Frederic Batteux, Amélie Servettaz, Amélie Servettaz   +11 more
doaj   +1 more source

The Political Economy of Patent Buyouts

The RAND Journal of Economics, Volume 57, Issue 2, Page 315-333, Summer 2026.
ABSTRACT Incentivizing innovation through buyouts may alleviate the social costs associated with patent power, but the political economy and feasibility of this potentially important financing mechanism have been understudied. We study an international setting of countries with different innovation and financing capabilities, and where financing ...
Amal Ahmad, Dominik Naeher, Sebastian Vollmer   +2 more
wiley   +1 more source

Childhood meningitis in Kuwait in the era of post pneumococcal conjugate vaccination: A multicenter study

Journal of Infection and Public Health, 2017
This is a retrospective study to evaluate epidemiology and etiologies of childhood meningitis in Kuwait after the routine introduction of the pneumococcal conjugate vaccine. The data was collected from 196 patients in the period of 2010–2014.
Hussain Sadeq, Entesar H. Husain, Amna Alkoot, Suha Atyani, Abdullah Al-fraij, Abdulrahman Al-Daithan, Talal AlSaleem, Anfal Taher, May Alenezi   +8 more
doaj   +1 more source

Vaccination in Kidney Transplant Candidates

Transplantation Direct, 2023
Background:. Kidney transplant (KT) candidates have historically low immunization rates against recommended vaccines. A retrospective single-center study of contemporary KT candidates was conducted to assess vaccination rates and vaccine uptake. Methods:.
Kiran Gajurel, MD, Tue Ngo, MD, MPH, Robert T. Fairman, PhD, MPH, Lewis H. McCurdy, MD   +3 more
doaj   +1 more source

Immunosenescence and Vaccine Efficacy in Aging: Dynamic Interplay of Gut Microbiota and mTOR Signaling Pathways

Aging Cell, Volume 25, Issue 6, June 2026.
Aging impairs vaccine efficacy through gut microbiota dysbiosis and mTOR hyperactivation, which together drive inflammaging and weaken immune memory. This review highlights the bidirectional microbiota–mTOR axis and proposes that combining mTOR inhibitors with microbiota modulation offers a promising strategy to enhance vaccine responses in older ...
Jiaxuan Li, Yuhong Zhang, Daijun Yu, Jianhua Li, Keda Chen, Lisheng Chu   +5 more
wiley   +1 more source