The New Era of Pneumococcal Vaccination in Adults: What Is Next?
Streptococcus pneumoniae remains the leading cause of community-acquired pneumonia in adults and bacterial meningitis in children worldwide. In addition to pneumonia, invasive pneumococcal diseases (IPDs), such as bacteremia and meningitis, pose a ...
Lale Ozisik
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Update on the success of the pneumococcal conjugate vaccine
Several years after the seven-valent pneumococcal conjugate vaccine (PCV7) was introduced in Canada and elsewhere, routine infant vaccination has led to near eradication of invasive pneumococcal disease caused by vaccine serotype strains in both children and adults.
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Experience with pneumococcal conjugate vaccine in Norway
Seven-valent pneumococcal conjugate vaccine (PCV7) was introduced into the Norwegian childhood vaccination program in July 2006 in a 2+1 dose (three-dose) schedule. Vaccine coverage quickly reached high levels and the incidence rate of invasive pneumococcal disease in children under 2 years of age declined rapidly.
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Pneumococcal conjugate vaccines—a European perspective
Streptococcus pneumoniae is a leading cause of bacterial pneumonia, meningitis, and acute otitis media in children and adults worldwide. In the age group of < 2 years the incidence of invasive pneumococcal disease ranges from approximately 14 cases per 100,000 in Germany and the Netherlands and more than 90 per 100,000 children in Spain.
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Background Vaccination of infants with pneumococcal conjugate vaccines is recommended by the World Health Organization. Evidence is mixed regarding the differences in immunogenicity and efficacy of the different pneumococcal vaccines.
Shuo Feng +13 more
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Adult Pneumococcal Vaccination in Latin America: The Next Step Beyond Pediatric Pneumococcal Conjugate Vaccine. [PDF]
Zavaleta-Monestel E +4 more
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Clonal expansion of global pneumococcal sequence cluster 3 within serotype 8 after 13-valent pneumococcal conjugate vaccine introduction, South Africa. [PDF]
Lekhuleni C +18 more
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Impact of a 21-valent pneumococcal conjugate vaccine on pneumococcal disease incidence among adults 65-84 years of age in Belgium: An epidemiological modeling study. [PDF]
Vandenplas Y +6 more
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Serotype-specific pneumococcal conjugate vaccine effectiveness in Canadian children: an indirect cohort study using Bayesian hierarchical modeling of multisite data. [PDF]
Zhou Z +8 more
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Inequalities in childhood pneumococcal conjugate vaccine uptake in England before and after the change from a 2 + 1 to 1 + 1 schedule: a longitudinal study. [PDF]
Ilechukwu P +3 more
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