Deletions in the neuraminidase stalk region of H2N2 and H9N2 avian influenza virus subtypes do not affect postinfluenza secondary bacterial pneumonia [PDF]
We investigated the synergism between influenza virus and Streptococcus pneumoniae, particularly the role of deletions in the stalk region of the neuraminidase (NA) of H2N2 and H9N2 avian influenza viruses.
Chen, Hongjun+8 more
core +1 more source
This review analyzes the data on prevalence and microbe picture of pneumococcal infections in the world and in Russia, based on the results of the proper studies and the literature data.
S.V. Sidorenko+4 more
doaj +2 more sources
The remaining challenges of pneumococcal disease in adults [PDF]
Pneumococcal disease can be divided into invasive disease, i.e. when bacteria are detected in normally sterile body fluids, and noninvasive disease. Pneumococcal disease occurs more frequently in younger children and older adults.
E. Ludwig+4 more
doaj
Development of primary invasive pneumococcal disease caused by serotype 1 pneumococci is driven by early increased type I interferon response in the lung [PDF]
The pneumococcus is the world's foremost respiratory pathogen, but the mechanisms allowing this pathogen to proceed from initial asymptomatic colonization to invasive disease are poorly understood.
Harvey, Richard M.+3 more
core +1 more source
Vaccination and antimicrobial therapy remain the cornerstones of the management of pneumococcal pneumonia. Despite significant successes, the capacity of the pneumococcus to evolve in the face of the selective pressure of anticapsular immunity challenges immunization programs.
David H. Dockrell+2 more
openaire +3 more sources
Nasopharyngeal S. pneumoniae carriage and density in Belgian infants after 9 years of pneumococcal conjugate vaccine programme [PDF]
Background: In Belgium, the infant pneumococcal conjugate vaccine (PCV) programme changed from PCV7 (2007-2011) to PCV13 (2011-2015) and to PCV10 (2015-2016). A 3-year nasopharyngeal carriage study was initiated during the programme switch in 2016.
Blaizot, Stéphanie+10 more
core +2 more sources
Has the incidence of empyema in Scottish children continued to increase beyond 2005? [PDF]
Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.Peer ...
Nath, Stuart+3 more
core +1 more source
Integrating tuberculosis and HIV services in low- and middle-income countries: a systematic review.
OBJECTIVES: Given the imperative to scale up integrated tuberculosis (TB) and HIV services in settings where both are of major public health importance, we aimed to synthesise knowledge concerning implementation of TB/HIV service integration.
Atun+36 more
core +1 more source
Genetic Variation in NFKBIE Is Associated With Increased Risk of Pneumococcal Meningitis in Children
Background: Streptococcus pneumoniae and Neisseria meningitidis are frequent pathogens in life-threatening infections. Genetic variation in the immune system may predispose to these infections.
Lene F. Lundbo+8 more
doaj +1 more source
Molecular epidemiology of pneumococci obtained from Gambian children aged 2-29 months with invasive pneumococcal disease during a trial of a 9-valent pneumococcal conjugate vaccine. [PDF]
BACKGROUND: The study describes the molecular epidemiology of Streptococcus pneumoniae causing invasive disease in Gambian children METHODS: One hundred and thirty-two S. pneumoniae isolates were recovered from children aged 2-29 months during the course
Adegbola, Richard A+14 more
core +2 more sources