Results 111 to 120 of about 76,076 (292)

Preventive measures in infancy to reduce under-five mortality: a case-control study in The Gambia.

open access: yes, 2009
OBJECTIVE: To investigate the relationship between child mortality and common preventive interventions: vaccination, trained birthing attendants, tetanus toxoid during pregnancy, breastfeeding and vitamin A supplementation. METHODS: Case-control study in
Adegbola, Richard A   +8 more
core   +1 more source

Epidemiological approaches to evaluate clinical unmasking of HPV‐associated cervical lesions in the HPV vaccination era

open access: yesInternational Journal of Cancer, Volume 158, Issue 4, Page 847-857, 15 February 2026.
Abstract HPV vaccination reduces the risk of developing HPV‐attributable cancers, including cervical cancer. However, an attenuation of HPV vaccine impact after the implementation of HPV vaccination may occur through clinical unmasking. Clinical unmasking is a distinct and complex phenomenon that arises in the absence of clinical interventions ...
Joseph E. Tota   +8 more
wiley   +1 more source

Impact of pneumococcal conjugate vaccination: a retrospective study of hospitalization for pneumonia in North-East Italy [PDF]

open access: yes, 2016
Introduction. Pneumonia remains a common reason for hospitalizing infants and the elderly worldwide, and streptococcal infection is often responsible. The aim of this study was to assess the burden of pneumonia in a large general population. Methods. All
Baldo, Vincenzo   +9 more
core   +1 more source

Optimizing community case management strategies to achieve equitable reduction of childhood pneumonia mortality:An application of Equitable Impact Sensitive Tool (EQUIST) in five low- and middle-income countries [PDF]

open access: yes, 2012
BACKGROUND: The aim of this study was to populate the Equitable Impact Sensitive Tool (EQUIST) framework with all necessary data and conduct the first implementation of EQUIST in studying cost–effectiveness of community case management of childhood ...
Agarwal   +26 more
core   +2 more sources

The ZNF148‐ZEB1‐AS1‐IGF2BP2‐NOD2 Axis Drives Microglial Antipneumococcal Immunity in Bacterial Meningitis

open access: yesGlia, Volume 74, Issue 2, February 2026.
ZNF148 upregulates ZEB1‐AS1, which scaffolds IGF2BP2 to stabilize NOD2 mRNA, enhancing microglial anti‐pneumococcal immunity via cytokine production and bacterial clearance in bacterial meningitis. ABSTRACT Streptococcus pneumoniae (Spn) meningitis remains a lethal central nervous system (CNS) infection with limited therapies. This study identifies the
Xiufu Hu   +6 more
wiley   +1 more source

Genetic Variation in NFKBIE Is Associated With Increased Risk of Pneumococcal Meningitis in Children

open access: yesEBioMedicine, 2016
Background: Streptococcus pneumoniae and Neisseria meningitidis are frequent pathogens in life-threatening infections. Genetic variation in the immune system may predispose to these infections.
Lene F. Lundbo   +8 more
doaj   +1 more source

Pulmonary Alveolar Proteinosis Complicated by Invasive Streptococcus pneumoniae Infection Requiring Extracorporeal Membrane Oxygenation: A Case Report

open access: yesAcute Medicine &Surgery, Volume 13, Issue 1, January/December 2026.
A rare case of autoimmune pulmonary alveolar proteinosis complicated by invasive Streptococcus pneumoniae infection was successfully managed with veno‐venous ECMO. ECMO enabled timely whole lung lavage during recovery from septic shock, which yielded atypical yellowish‐brown fluid likely reflecting infection and led to clinical improvement.
Utaho Mizusawa   +8 more
wiley   +1 more source

Epidemiology of S. pneumoniae serotypes in the Russian Federation [PDF]

open access: yesКлиническая микробиология и антимикробная химиотерапия, 2017
The prevalence of the common serotypes of S. pneumoniae in the Russian Federation was estimated in healthy carriers as well as children and adult patients with invasive and non-invasive pneumococcal infections based on the epidemiological microbiological
Muravyev A.A.   +2 more
doaj  

Streptococcus pneumoniae HtrA is a dynamic and monomeric virulence factor capable of forming larger oligomeric complexes

open access: yesProtein Science, Volume 35, Issue 1, January 2026.
Abstract High‐temperature requirement A (HtrA) proteases are a conserved family of serine proteases central to protein quality control and bacterial virulence. While Gram‐negative and human HtrAs are structurally well studied, Gram‐positive homologs remain essentially uncharacterized.
Eunjeong Lee   +14 more
wiley   +1 more source

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