Results 91 to 100 of about 91,384 (208)

Perceptions of measles, pneumonia, and meningitis vaccines among caregivers in Shanghai, China, and the health belief model: a cross-sectional study

BMC Pediatrics, 2017
Background In China, the measles vaccine is offered for free whereas the pneumococcal vaccine is a for-fee vaccine. This difference has the potential to influence how caregivers evaluate whether a vaccine is important or necessary for their child, but it
Abram L. Wagner, Matthew L. Boulton, Xiaodong Sun, Bhramar Mukherjee, Zhuoying Huang, Irene A. Harmsen, Jia Ren, Brian J. Zikmund-Fisher   +7 more
doaj   +1 more source

Adjuvant glycerol is not beneficial in experimental pneumococcal meningitis [PDF]

, 2010
Bacterial meningitis in children causes high rates of mortality and morbidity. In a recent clinical trial, oral glycerol significantly reduced severe neurological sequelae in paediatric meningitis caused by Haemophilus influenzae type b, and a tendency ...
Grandgirard, Denis, Blaser, Cornelia, Klein, Matthias, Wittwer, Matthias, Weigand, Michael, Leib, Stephen L., Peltola, Heikki, Koedel, Uwe   +7 more
core   +2 more sources

Tuberculous meningitis: new tools and new approaches required [version 1; peer review: not peer reviewed] [PDF]

, 2019
Tuberculous meningitis is the most severe form of tuberculosis and causes widespread mortality and morbidity. Understanding of the epidemiology and pathogenesis is incomplete, and the optimal diagnosis and treatment are poorly defined.
Thwaites, Guy, International Tuberculous Meningitis Research Consortium, Seddon, James   +2 more
core   +1 more source

The impact of childhood pneumococcal vaccination on hospital admissions in England: a whole population observational study

BMC Infectious Diseases, 2019
Background Pneumococcal infections are major causes of morbidity and mortality worldwide. We use routine hospital admissions data and time-series modelling analysis to estimate the impact of the seven and thirteen valent pneumococcal conjugate vaccines ...
Tinevimbo Shiri, Noel D. McCarthy, Stavros Petrou   +2 more
doaj   +1 more source

Extracellular calcium reduction strongly increases the lytic capacity of pneumolysin from streptococcus pneumoniae in brain tissue [PDF]

, 2011
Background. Streptococcus pneumoniae causes serious diseases such as pneumonia and meningitis. Its major pathogenic factor is the cholesterol-dependent cytolysin pneumolysin, which produces lytic pores at high concentrations.
Elke Maier, Fortsch, C., Mitchell, T.J., Benz, Roland, Ma, Jiangtao, Christina Förtsch, Sabrina Hupp, Jiangtao Ma, Timothy J. Mitchell, Iliev, A. I., Maier, Elke, Förtsch, Christina, Maier, E., Hupp, Sabrina, Asparouh I. Iliev, Hupp, S., Mitchell, Timothy J, Roland Benz, Wippel, C., Benz, R., Ma, J., Wippel, Carolin, Iliev, Asparouh I, Carolin Wippel   +23 more
core   +1 more source

PNEUMOCOCCAL MENINGITIS [PDF]

BMJ, 1917
C, Worster-Drought, A M, Kennedy
openaire   +2 more sources

Seasonality and outbreak of a predominant Streptococcus pneumoniae serotype 1 clone from The Gambia: expansion of ST217 hypervirulent clonal complex in West Africa. [PDF]

, 2008
BACKGROUND: Streptococcus pneumoniae serotype 1 causes > 20% of invasive disease, among all age groups combined, in The Gambia. In contrast, it is rarely detected in carriage studies. This study compares the molecular epidemiology of S.
Greenwood, Brian M, Martin Antonio, Uzochukwu Egere, Egere Uzochukwu, Akisanya, Abiodun, Sankareh Kawsu, George Lahai, Kawsu Sankareh, Timothy Awine, Nsekpong, David, Lahai George, Hakeem Ishrat, Zaman, Syed MA, Hill Philip C, Syed MA Zaman, Awine, Timothy, Egere, Uzochukwu, Secka, Ousman, Sankareh, Kawsu, Awine Timothy, Richard A Adegbola, Godwin Enwere, Ousman Secka, Philip C Hill, Felicity Cutts, Akisanya Abiodun, Nsekpong David, Lahai, George, Cutts Felicity, Secka Ousman, Hakeem, Ishrat, Cutts, Felicity, Antonio Martin, Enwere Godwin, Tumani Corrah, Corrah, Tumani, Adegbola Richard A, Hill, Philip C, Brian M Greenwood, Adegbola, Richard A, David Nsekpong, Corrah Tumani, Enwere, Godwin, Zaman Syed MA, Greenwood Brian M, Antonio, Martin, Ishrat Hakeem, Abiodun Akisanya   +47 more
core   +1 more source

African meningitis belt pneumococcal disease epidemiology indicates a need for an effective serotype 1 containing vaccine, including for older children and adults

BMC Infectious Diseases, 2010
Background Pneumococcal conjugate vaccine strategies in GAVI-eligible countries are focusing on infant immunization but this strategy may not be optimal in all settings.
Mueller Judith E, Gessner Bradford D, Yaro Seydou   +2 more
doaj   +1 more source

The alveolar microenvironment of patients infected with human immunodeficiency virus does not modify alveolar macrophage interactions with Streptococcus pneumoniae. [PDF]

, 2013
We tested the hypothesis that HIV infection results in activation of alveolar macrophages and that this might be associated with impaired defense against pneumococcus. We compared alveolar macrophages and lymphocytes in 131 bronchoalveolar lavage samples
Pridmore, Alison, Molyneux, Malcolm E, Molyneux, Malcolm E., Jagoe, R Thomas, Gordon, Stephen, Zijlstra, Eduard E, Jarman, Elizabeth R., North, James C., Read, Robert C., French, Neil, Read, Robert C, Gordon, Stephen B., Musaya, Janelisa, North, James C, Gordon, Stephen B, Jarman, Elizabeth R, Jagoe, R. Thomas, Zijlstra, Eduard E.   +17 more
core   +1 more source

Genetic Variation in NFKBIE Is Associated With Increased Risk of Pneumococcal Meningitis in Children

EBioMedicine, 2016
Background: Streptococcus pneumoniae and Neisseria meningitidis are frequent pathogens in life-threatening infections. Genetic variation in the immune system may predispose to these infections.
Lene F. Lundbo, Zitta Barrella Harboe, Louise N. Clausen, Mads V. Hollegaard, Henrik T. Sørensen, David M. Hougaard, Helle B. Konradsen, Mette Nørgaard, Thomas Benfield   +8 more
doaj   +1 more source