Serotype Distribution of Remaining Pneumococcal Meningitis in the Mature PCV10/13 Period: Findings from the PSERENADE Project [PDF]
Microorganisms, 2021 Pneumococcal conjugate vaccine (PCV) introduction has reduced pneumococcal meningitis incidence. The Pneumococcal Serotype Replacement and Distribution Estimation (PSERENADE) project described the serotype distribution of remaining pneumococcal ...
Maria Garcia Quesada +49 more
doaj +2 more sources
Bacteremia causes hippocampal apoptosis in experimental pneumococcal meningitis [PDF]
BMC Infectious Diseases, 2010 Background Bacteremia and systemic complications both play important roles in brain pathophysiological alterations and the outcome of pneumococcal meningitis.
Rowland Ian +3 more
doaj +2 more sources
Delayed cerebral thrombosis complicating pneumococcal meningitis: an autopsy study
Annals of Intensive Care, 2018 Background Delayed cerebral thrombosis (DCT) is a devastating cerebrovascular complication in patients with excellent initial recovery of pneumococcal meningitis.
Joo-Yeon Engelen-Lee +3 more
doaj +2 more sources
Continued occurrence of serotype 1 pneumococcal meningitis in two regions located in the meningitis belt in Ghana five years after introduction of 13-valent pneumococcal conjugate vaccine. [PDF]
PLoS ONE, 2018 BACKGROUND:Increases in pneumococcal meningitis were reported from Ghanaian regions that lie in the meningitis belt in 2016-2017, despite introduction of 13-valent pneumococcal conjugate vaccine (PCV13) in 2012 using a 3-dose schedule (6, 10, and 14 ...
Catherine H Bozio +11 more
doaj +1 more source
Penicillin Resistant Pneumococcal Meningitis in Paediatric Trauma Patient [PDF]
Journal of Clinical and Diagnostic Research, 2018 Pneumococcal meningitis is a life-threatening infection, requiring prompt diagnosis and effective treatment. The approach to therapy in patients with pneumococcal meningitis has changed considerably over the past 20 years because of emerging penicillin ...
Vijeta Bajpai +3 more
doaj +1 more source
PNEUMOCOCCAL MENINGITIS IN ADULTS [PDF]
Annals of Internal Medicine, 1952 Excerpt Despite numerous recent optimistic reports concerning the rate of cure in pneumococcal meningitis, a review of 22 adult cases observed at the Morrisania City Hospital from 1943 through June...
J S, FEIBUSH, E J, MURPHY, A, LUBART
openaire +2 more sources
Acta Neuropathologica Communications, 2021 Background Patients with pneumococcal meningitis are at risk for death and neurological sequelae including cognitive impairment. Functional genetic polymorphisms of macrophage migration inhibitory factor (MIF) alleles have shown to predict mortality of ...
Anne T. Kloek +6 more
doaj +1 more source
The role of plasminogen activator inhibitor-2 in pneumococcal meningitis
Acta Neuropathologica Communications, 2022 Pneumococcal meningitis is associated with dysregulation of the coagulation cascade. Previously, we detected upregulation of cerebral plasminogen activator inhibitor-2 (PAI-2) mRNA expression during pneumococcal meningitis.
Nina C. Teske +8 more
doaj +1 more source
Meningococcal and pneumococcal meningitis in Northern Ghana [PDF]
, 2008 Despite improvements in technology, treatments and understanding of how bacterial meningitis develops, the disease remains a potentially life-threatening emergency capable of causing significant morbidity and mortality. N. meningitidis, S.
Forgor, Abdulai Adams
core +1 more source
Apoptosis is essential for neutrophil functional shutdown and determines tissue damage in experimental pneumococcal meningitis. [PDF]
, 2009 During acute bacterial infections such as meningitis, neutrophils enter the tissue where they combat the infection before they undergo apoptosis and are taken up by macrophages.
Häcker Georg +20 more
core +1 more source