Results 21 to 30 of about 20,003 (217)

Pneumococcal Meningitis in Adults after Introduction of PCV7 and PCV13, Israel, July 2009–June 2015

Emerging Infectious Diseases, 2018
The indirect effect of pneumococcal conjugate vaccine on adult pneumococcal meningitis has not been thoroughly investigated. We present data from active surveillance on pneumococcal meningitis in adults in Israel occurring during July 2009–June 2015 ...
Gili Regev-Yochay, Klaris Reisenberg, Michal Katzir, Yonit Wiener-Well, Galia Rahav, Jacob Strahilevitz, Valery Istomin, Evgenia Tsyba, Avi Peretz, Shirley Khakshoor, Ron Dagan   +10 more
doaj   +1 more source

Effect of Pneumococcal Conjugate Vaccines on Pneumococcal Meningitis, England and Wales, July 1, 2000–June 30, 2016

Emerging Infectious Diseases, 2019
We describe the effects of the 7-valent (PCV7) and 13-valent (PCV13) pneumococcal conjugate vaccines on pneumococcal meningitis in England and Wales during July 1, 2000–June 30, 2016.
Godwin Oligbu, Sarah Collins, Abdelmajid Djennad, Carmen L. Sheppard, Norman K. Fry, Nick J. Andrews, Ray Borrow, Mary E. Ramsay, Shamez N. Ladhani   +8 more
doaj   +1 more source

Leukocyte attraction by CCL20 and its receptor CCR6 in humans and mice with pneumococcal meningitis.

PLoS ONE, 2014
We previously identified CCL20 as an early chemokine in the cerebrospinal fluid (CSF) of patients with pneumococcal meningitis but its functional relevance was unknown.
Matthias Klein, Matthijs C Brouwer, Barbara Angele, Madelijn Geldhoff, Gabriel Marquez, Rosa Varona, Georg Häcker, Helga Schmetzer, Hans Häcker, Sven Hammerschmidt, Arie van der Ende, Hans-Walter Pfister, Diederik van de Beek, Uwe Koedel   +13 more
doaj   +1 more source

Common NFKBIL2 polymorphisms and susceptibility to pneumococcal disease: a genetic association study. [PDF]

, 2010
INTRODUCTION: Streptococcus pneumoniae remains a major global health problem and a leading cause of death in children worldwide. The factors that influence development of pneumococcal sepsis remain poorly understood, although increasing evidence points ...
Rautanen, Anna, Moore, CE, Davies, RJ, J Scott, Adrian VS Hill, Shelley Segal, Berkley, James, Hill, Adrian, Chiea C Khor, Andrew Walley, Catrin E Moore, Hill, AVS, Peshu, N, Davies, Robert JO, Scott, John, Williams, TN, Chapman, Stephen J, James A Berkley, Segal, S, Rautanen, A, Hill, AV, Scott, J Anthony, Fredrik O Vannberg, Walley, A, Khor, Chiea C, Vannberg, Fredrik O, Davies, RJO, Khor, CC, Derrick W Crook, Crook, DW, Moore, Catrin E, Berkley, James A, Segal, Shelley, Berkley, JA, Norbert Peshu, Hill, Adrian VS, Crook, Derrick W, Thomas N Williams, Day, Nicholas P, Day, NP, Vannberg, FO, Peshu, Norbert, Chapman, SJ, Scott, JA, Stephen J Chapman, Nicholas P Day, Anna Rautanen, Williams, Thomas N, Day, Nicholas, Walley, Andrew, Williams, Thomas, Robert JO Davies   +51 more
core   +1 more source

Pneumococcal antibody concentrations and carriage of pneumococci more than 3 years after infant immunization with a pneumococcal conjugate vaccine. [PDF]

, 2012
BACKGROUND: A 9-valent pneumococcal conjugate vaccine (PCV-9), given in a 3-dose schedule, protected Gambian children against pneumococcal disease and reduced nasopharyngeal carriage of pneumococci of vaccine serotypes.
Greenwood, Brian M, Godwin C. Enwere, Brown J Okoko, Nsekpong, Ekpedeme D, Godwin C Enwere, Ekpedeme D Nsekpong, Syed M. A. Zaman, Aderonke A. Odutola, Saaka, Mark, Zaman, Syed MA, Akinsola, Adebayo K, Richard A. Adegbola, Syed M A Zaman, Adebayo K. Akinsola, Aderonke A Odutola, Richard A Adegbola, Martin O. C. Ota, Okoko, Brown J, Odutola, Aderonke A, Martin O C Ota, Cutts, Felicity T, Felicity T Cutts, Ekpedeme D. Nsekpong, Felicity T. Cutts, Adebayo K Akinsola, Brown J. Okoko, Enwere, Godwin C, Brian M Greenwood, Mark Saaka, Adegbola, Richard A, Brian M. Greenwood, Ota, Martin OC   +31 more
core   +1 more source

Global impact of 10- and 13-valent pneumococcal conjugate vaccines on pneumococcal meningitis in all ages: The PSERENADE project [PDF]

Journal of Infection
Brita A Winje, Palle Valentiner-Branth, J Pekka Nuorti   +2 more
exaly   +2 more sources

The Pathophysiology of Pneumococcal Meningitis

Annals of Medicine, 1994
The interactions between pneumococcal surface components and host defence systems that initiate pneumococcal meningitis have been studied in considerable molecular detail over the past decade. In this sense, the pneumococcus has served as a prototype for the unravelling of the genesis of inflammation caused by gram-positive bacteria.
B, Spellerberg, E I, Tuomanen
openaire   +2 more sources

Genome analysis of a highly virulent serotype 1 strain of streptococcus pneumoniae from West Africa [PDF]

, 2012
Streptococcus pneumoniae is a leading cause of pneumonia, meningitis, and bacteremia, estimated to cause 2 million deaths annually. The majority of pneumococcal mortality occurs in developing countries, with serotype 1 a leading cause in these areas.
Loman Nicholas J., Martin Antonio, Nicholas J Loman, Tiffany M. Williams (126277), Richard A. Adegbola (20657), Pallen, Mark J., Tiffany M. Williams, Weinstock, George M, Mark J. Pallen, Williams, Tiffany M., Loman, Nicholas J., Weinstock, George M., Martin Antonio (42317), Musher, Daniel M., George M. Weinstock, Musher Daniel M., Richard A. Adegbola, Adegbola, Richard A., Richard A Adegbola, Mark J Pallen, George M Weinstock, Daniel M. Musher, Loman, Nicholas J, Nicholas J. Loman (126279), Ebruke Chinelo, Pallen, Mark J, Weinstock George M., Tiffany M Williams, Antonio Martin, Williams, Tiffany M, Ebruke, Chinelo, Daniel M Musher, Mark J. Pallen (8904), Williams Tiffany M., Adegbola Richard A., Pallen Mark J., George M. Weinstock (43281), Daniel M. Musher (126285), Adegbola, Richard A, Chinelo Ebruke (126282), Musher, Daniel M, Antonio, Martin, Nicholas J. Loman, Chinelo Ebruke   +43 more
core   +1 more source

Trends in incidence of pneumococcal disease before introduction of conjugate vaccine: South West England, 1996-2005. [PDF]

, 2008
Introduction of pneumococcal conjugate and polysaccharide vaccines into the United Kingdom's routine immunization programmes is expected to change the epidemiology of invasive pneumococcal disease (IPD).
Dance, DA, Smith, M. D., George, RC, Waight, P., Christensen, H, South West Pneumococcus Study Group, George, R. C., Ihekweazu, Chikwe A., Smith, MD, Stuart, J. M., Dance, DAB, Stuart, JM, SW Pneumococcal Group, Cartwright, KAV, Ihekweazu, CA, Dance, D. A.B., Cartwright, KA, Pebody, R, Christensen, H., Pebody, R., Waight, P, Fletcher, Margaret   +21 more
core   +1 more source

Clinical outcome of pneumococcal meningitis during the emergence of pencillin-resistant Streptococcus pneumoniae: an observational study

BMC Infectious Diseases, 2011
Background Prior to the availability of generic third-generation cephalosporins, penicillins were widely used for treatment of pneumococcal meningitis in developing countries despite concerns about rising levels of penicillin resistance among ...
Gouveia Edilane L, Reis Joice N, Flannery Brendan, Cordeiro Soraia M, Lima Josilene BT, Pinheiro Ricardo M, Salgado Kátia, Mascarenhas Ana, Carvalho M Gloria, Beall Bernard W, Reis Mitermayer G, Ko Albert I   +11 more
doaj   +1 more source