Burden of Severe Pneumonia, Pneumococcal Pneumonia and Pneumonia Deaths in Indian States: Modelling Based Estimates. [PDF]
PLoS ONE, 2015 The burden of severe pneumonia in terms of morbidity and mortality is unknown in India especially at sub-national level. In this context, we aimed to estimate the number of severe pneumonia episodes, pneumococcal pneumonia episodes and pneumonia deaths ...
Habib Farooqui +3 more
doaj +26 more sources
Estimating the burden of pneumococcal pneumonia among adults: a systematic review and meta-analysis of diagnostic techniques. [PDF]
PLoS ONE, 2013 BackgroundPneumococcal pneumonia causes significant morbidity and mortality among adults. Given limitations of diagnostic tests for non-bacteremic pneumococcal pneumonia, most studies report the incidence of bacteremic or invasive pneumococcal disease ...
Maria A Said +47 more
doaj +2 more sources
Epidemiology of Pneumococcal Pneumonia in Louisville, Kentucky, and Its Estimated Burden of Disease in the United States [PDF]
Microorganisms, 2023 Streptococcus pneumoniae remains a primary pathogen in hospitalized patients with community-acquired pneumonia (CAP). The objective of this study was to define the epidemiology of pneumococcal pneumonia in Louisville, Kentucky, and to estimate the burden
Julio Ramirez +12 more
doaj +2 more sources
MicroRNA-223 Dampens Pulmonary Inflammation during Pneumococcal Pneumonia [PDF]
Cells, 2023 Community-acquired pneumonia remains a major contributor to global communicable disease-mediated mortality. Neutrophils play a leading role in trying to contain bacterial lung infection, but they also drive detrimental pulmonary inflammation, when ...
Cengiz Goekeri +18 more
doaj +2 more sources
Neutrophil Recruitment in Pneumococcal Pneumonia [PDF]
Frontiers in Cellular and Infection Microbiology, 2022 Streptococcus pneumoniae (Spn) is the primary agent of community-acquired pneumonia. Neutrophils are innate immune cells that are essential for bacterial clearance during pneumococcal pneumonia but can also do harm to host tissue. Neutrophil migration in
Catherine S. Palmer +1 more
doaj +2 more sources
Second reported outbreak of pneumococcal pneumonia among shipyard employees in Turku, Finland, August-October 2023: a case-control study. [PDF]
Epidemiol InfectKitowska W +9 more
europepmc +3 more sources
Frontiers in Cellular and Infection Microbiology, 2020 New diagnostic tests for the etiology of childhood pneumonia are needed. We evaluated the antibody-in-lymphocyte supernatant (ALS) assay to detect immunoglobulin (Ig) G secretion from ex vivo peripheral blood mononuclear cell (PBMC) culture, as a ...
Michael J. Carter +36 more
doaj +1 more source
Insights into pneumococcal pneumonia using lung aspirates and nasopharyngeal swabs collected from pneumonia patients in The Gambia. [PDF]
, 2020 We investigated the pathogenesis of pneumococcal pneumonia using clinical specimens collected for pneumonia surveillance in The Gambia. Lung aspirates and nasopharyngeal swabs from 31 patients were examined by culture, qPCR, whole genome sequencing ...
Dunne, EM +10 more
core +4 more sources
Clinical and Microbiological Factors Associated with High Nasopharyngeal Pneumococcal Density in Patients with Pneumococcal Pneumonia. [PDF]
PLoS ONE, 2015 We aimed to study if certain clinical and/or microbiological factors are associated with a high nasopharyngeal (NP) density of Streptococcus pneumoniae in pneumococcal pneumonia.
Helena Alpkvist +7 more
doaj +1 more source
Journal of Biomedical Science, 2020 Background Pneumococcal conjugate vaccine (PCV) reduces both invasive pneumococcal disease (IPD) and other pneumococcal infections worldwide. We investigated the impact of stepwise implementation of childhood PCV programs on the prevalence of ...
Ching-Fen Shen +10 more
doaj +1 more source