Assessment of an Antibody-in-Lymphocyte Supernatant Assay for the Etiological Diagnosis of Pneumococcal Pneumonia in Children [PDF]
Frontiers in Cellular and Infection Microbiology, 2020 New diagnostic tests for the etiology of childhood pneumonia are needed. We evaluated the antibody-in-lymphocyte supernatant (ALS) assay to detect immunoglobulin (Ig) G secretion from ex vivo peripheral blood mononuclear cell (PBMC) culture, as a ...
Michael J. Carter +36 more
doaj +5 more sources
Estimating the burden of pneumococcal pneumonia among adults: a systematic review and meta-analysis of diagnostic techniques. [PDF]
PLoS ONE, 2013 Pneumococcal pneumonia causes significant morbidity and mortality among adults. Given limitations of diagnostic tests for non-bacteremic pneumococcal pneumonia, most studies report the incidence of bacteremic or invasive pneumococcal disease (IPD), and ...
Maria A Said +47 more
doaj +3 more sources
Use of procalcitonin and C-reactive protein to evaluate vaccine efficacy against pneumonia. [PDF]
PLoS Medicine, 2005 Pneumonia remains the leading cause of death in young children. The poor specificity of chest radiographs (CXRs) to diagnose pneumococcal pneumonia may underestimate the efficacy of pneumococcal conjugate vaccine in preventing pneumococcal pneumonia.The ...
Shabir A Madhi +3 more
doaj +6 more sources
Burden of Severe Pneumonia, Pneumococcal Pneumonia and Pneumonia Deaths in Indian States: Modelling Based Estimates. [PDF]
PLoS ONE, 2015 The burden of severe pneumonia in terms of morbidity and mortality is unknown in India especially at sub-national level. In this context, we aimed to estimate the number of severe pneumonia episodes, pneumococcal pneumonia episodes and pneumonia deaths ...
Habib Farooqui +3 more
doaj +11 more sources
Impact of Pneumococcal Conjugate Vaccination of Infants on Pneumonia and Influenza Hospitalization and Mortality in All Age Groups in the United States [PDF]
mBio, 2011 A seven-valent pneumococcal conjugate vaccine (PCV7) introduced in the United States in 2000 has been shown to reduce invasive pneumococcal disease (IPD) in both vaccinated children and adults through induction of herd immunity. We assessed the impact of
Lone Simonsen +5 more
doaj +4 more sources
Molecular pathogenesis of pneumococcal pneumonia [PDF]
Frontiers in Bioscience, 2001 The past two decades have witnessed an explosion of data on the molecular pathogenesis of pneumonia caused by Streptococcus pneumoniae, one of the most important pathogens currently plaguing man. Identification and functional analysis of genes and their proteins, elucidation of mechanisms involved in adherence, colonization, inflammation, and invasion,
A. McCullers Jonathan
openalex +4 more sources
Clinical outcomes of pneumococcal pneumonia caused by antibiotic-resistant strains in Asian countries: a study by the Asian network for surveillance of resistant pathogens [PDF]
, 2004 To evaluate the clinical outcomes of pneumococcal pneumonia caused by antibiotic-resistant strains in Asian countries, we performed a prospective observational study of 233 cases of adult pneumococcal pneumonia in 9 Asian countries from January 2000 to ...
Carlos, Celia Carpio +19 more
core +3 more sources
COVID‐19 and myasthenia gravis: A review of neurological implications of the SARS‐COV‐2
Brain and Behavior, Volume 12, Issue 12, December 2022., 2022 Abstract Introduction This review highlights the potential mechanisms of neuromuscular manifestation of COVID‐19, especially myasthenia gravis (MG). Methods An extensive literature search was conducted by two independent investigators using PubMed/MEDLINE and Google Scholar from its inception to December 2020. Results Exacerbations of clinical symptoms
Syed Muhammad Ismail Shah +10 more
wiley +1 more source
Insights into pneumococcal pneumonia using lung aspirates and nasopharyngeal swabs collected from pneumonia patients in The Gambia. [PDF]
, 2020 We investigated the pathogenesis of pneumococcal pneumonia using clinical specimens collected for pneumonia surveillance in The Gambia. Lung aspirates and nasopharyngeal swabs from 31 patients were examined by culture, qPCR, whole genome sequencing ...
Dunne, EM +10 more
core +3 more sources
Development and implementation of an aspiration pneumonia cause investigation algorithm
The Clinical Respiratory Journal, Volume 17, Issue 1, Page 20-28, January 2023., 2023 Aspiration pneumonia remains an underdiagnosed and unestablished diagnosis. We propose the use of an algorithm (developed based on the JRS guidelines) to enable adequate management of older adults with pneumonia. When implemented in an acute setting, the algorithm enhanced the diagnosis of causative conditions, swallow screening, and preventative ...
Yuki Yoshimatsu +8 more
wiley +1 more source