Results 1 to 10 of about 383,894 (265)

Neutrophil Recruitment in Pneumococcal Pneumonia [PDF]

Frontiers in Cellular and Infection Microbiology, 2022
Streptococcus pneumoniae (Spn) is the primary agent of community-acquired pneumonia. Neutrophils are innate immune cells that are essential for bacterial clearance during pneumococcal pneumonia but can also do harm to host tissue. Neutrophil migration in
Catherine S. Palmer, Jacqueline M. Kimmey   +1 more
doaj   +3 more sources

Pneumococcal pneumonia [PDF]

Thorax, 2019
Pneumococcal conjugate vaccines (PCV) were first licensed in 2000 and have been introduced into national immunisation programme in more than 145 countries.
David Goldblatt, Elizabeth Miller
openaire   +5 more sources

Invasive pneumococcal disease, pneumococcal pneumonia and all-cause pneumonia in Hong Kong during the COVID-19 pandemic compared with the preceding 5 years: a retrospective observational study

BMJ Open, 2021
Objectives To compare the incidence and severity of invasive pneumococcal diseases (IPDs), pneumococcal pneumonia and all-cause pneumonia during the COVID-19 pandemic period with universal masking and social distancing with that of previous 5 years ...
Pak-leung Ho, King-Pui Florence Chan, Ting-Fung Ma, Mary Sau-Man Ip   +3 more
doaj   +2 more sources

Prevalence, Clinical Severity, and Serotype Distribution of Pneumococcal Pneumonia Among Adults Hospitalized With Community-Acquired Pneumonia in Tennessee and Georgia, 2018-2022. [PDF]

Clin Infect Dis
Introduction Understanding the pneumococcal serotypes causing community-acquired pneumonia (CAP) is essential for evaluating the impact of pneumococcal vaccines.
Self WH, Johnson KD, Resser JJ, Whitney CG, Baughman A, Kio M, Grijalva CG, Traenkner J, Johnson J, Miller KF, Rostad CA, Yildirim I, Salazar L, Tanios R, Swan SA, Zhu Y, Han JH, Weiss T, Roberts C, Rouphael N, PNEUMO Study Investigators.   +20 more
europepmc   +2 more sources

Epidemiology of Pneumococcal Pneumonia in Louisville, Kentucky, and Its Estimated Burden of Disease in the United States [PDF]

Microorganisms, 2023
Streptococcus pneumoniae remains a primary pathogen in hospitalized patients with community-acquired pneumonia (CAP). The objective of this study was to define the epidemiology of pneumococcal pneumonia in Louisville, Kentucky, and to estimate the burden
Julio Ramirez, Stephen Furmanek, Thomas R. Chandler, Timothy Wiemken, Paula Peyrani, Forest Arnold, William Mattingly, Ashley Wilde, Jose Bordon, Rafael Fernandez-Botran, Ruth Carrico, Rodrigo Cavallazzi, The University of Louisville Pneumonia Study Group   +12 more
doaj   +2 more sources

Influence of Older Age and Other Risk Factors on Pneumonia Hospitalization in Switzerland in the Pneumococcal Vaccine Era

Frontiers in Medicine, 2019
Background: Pneumococcal pneumonia is a disease of the extremes of age. However, as other traditional risk factors for pneumococcal pneumonia also increase with older age, it is unclear if older age itself should be an indication for pneumococcal ...
Werner C. Albrich, Frank Rassouli, Frederike Waldeck, Christoph Berger, Florent Baty   +4 more
doaj   +2 more sources

Btk inhibitor ibrutinib reduces inflammatory myeloid cell responses in the lung during murine pneumococcal pneumonia

Molecular Medicine, 2019
Background Streptococcus pneumoniae is a major causative agent in community-acquired pneumonia and sepsis. Overwhelming lung inflammation during pneumococcal pneumonia may hamper lung function.
Alexander P. de Porto, Zhe Liu, Regina de Beer, Sandrine Florquin, Onno J. de Boer, Rudi W. Hendriks, Tom van der Poll, Alex F. de Vos   +7 more
doaj   +2 more sources

MicroRNA-223 Dampens Pulmonary Inflammation during Pneumococcal Pneumonia [PDF]

Cells, 2023
Community-acquired pneumonia remains a major contributor to global communicable disease-mediated mortality. Neutrophils play a leading role in trying to contain bacterial lung infection, but they also drive detrimental pulmonary inflammation, when ...
Cengiz Goekeri, Peter Pennitz, Wibke Groenewald, Ulrike Behrendt, Holger Kirsten, Christian M. Zobel, Sarah Berger, Gitta A. Heinz, Mir-Farzin Mashreghi, Sandra-Maria Wienhold, Kristina Dietert, Anca Dorhoi, Achim D. Gruber, Markus Scholz, Gernot Rohde, Norbert Suttorp, CAPNETZ Study Group, Martin Witzenrath, Geraldine Nouailles   +18 more
doaj   +2 more sources

Polyamine transporter in Streptococcus pneumoniae is essential for evading early innate immune responses in pneumococcal pneumonia [PDF]

Scientific Reports, 2016
Streptococcus pneumoniae is the most common bacterial etiology of pneumococcal pneumonia in adults worldwide. Genomic plasticity, antibiotic resistance and extreme capsular antigenic variation complicates the design of effective therapeutic strategies ...
N. Aswathy, Justin A. Thornton, John V. Stokes, Imran Sunesara, Edwin Swiatlo, Bindu Nanduri   +5 more
openalex   +2 more sources

Pneumococcal carriage and disease in adults hospitalised with community-acquired pneumonia in Mongolia: prospective pneumonia surveillance program (2019–2022)

Pneumonia
Background Streptococcus pneumoniae is an important cause of pneumonia in older adults, however, serotyping and indirect impact information from low and middle-income countries is lacking. Mongolia has a childhood 13-valent pneumococcal conjugate vaccine
Tuya Mungun, Munkhchuluun Ulziibayar, Cattram D. Nguyen, Purevsuren Batsaikhan, Bujinlkham Suuri, Dashtseren Luvsantseren, Dorj Narangerel, Bilegtsaikhan Tsolmon, Lien Anh Ha Do, Darren Suryawijaya Ong, Belinda D. Ortika, Casey L. Pell, Laura K. Boelsen, Ashleigh C. Wee-Hee, Leena Spry, Jason Hinds, Michael W. Pride, Eileen M. Dunne, Bradford D. Gessner, E. Kim Mulholland, Catherine Satzke, Claire von Mollendorf   +21 more
doaj   +2 more sources