Results 61 to 70 of about 60,087 (267)

Bronchoscopy Identifies Bacterial Airway Colonization and Comorbidities in Preschool Children With Refractory Respiratory Symptoms: A Retrospective Study

Pediatric Pulmonology, Volume 61, Issue 1, January 2026.
ABSTRACT Background Preschool children with refractory respiratory symptoms often undergo diagnostic bronchoscopy to exclude anatomical and functional abnormalities and to detect suspected chronic lower respiratory tract infections by bronchoalveolar lavage (BAL).
Helena Donath, Julius Ruff, Laura Heumüller, Olaf Eickmeier, Melanie Dressler, Ralf Schubert, Katharina Blumchen, Johannes Schulze, Stefan Zielen, Jordis Trischler   +9 more
wiley   +1 more source

Cross-sectional study on attitudes among general practitioners towards pneumococcal vaccination for middle-aged and elderly population in Hong Kong. [PDF]

PLoS ONE, 2013
OBJECTIVE: To study the attitudes among general practitioners towards pneumococcal vaccination for middle-aged (50-64) and elderly population (over 65) in Hong Kong and the factors affecting their decision to advise pneumococcal vaccination for those age
Lancelot W H Mui, Alvin Y S Chan, Albert Lee, John Lee   +3 more
doaj   +1 more source

Evaluation of Pneumococcal Load in Blood by Polymerase Chain Reaction for the Diagnosis of Pneumococcal Pneumonia in Young Children in the PERCH Study. [PDF]

, 2017
BACKGROUND.: Detection of pneumococcus by lytA polymerase chain reaction (PCR) in blood had poor diagnostic accuracy for diagnosing pneumococcal pneumonia in children in 9 African and Asian sites.
Ahmed, Dilruba, Antonio, Martin, Awori, Juliet O, Baggett, Henry C, Baillie, Vicky L, Brooks, W Abdullah, Chipeta, James, Deloria Knoll, Maria, Deluca, Andrea N, Dione, Michel, Driscoll, Amanda J, Feikin, Daniel R, Hammitt, Laura L, Higdon, Melissa M, Howie, Stephen RC, Jatapai, Anchalee, Karron, Ruth A, Kotloff, Karen L, Levine, Orin S, Madhi, Shabir A, Mazumder, Razib, Moore, David P, Morpeth, Susan C, Murdoch, David R, Mwansa, James, Nyongesa, Sammy, O'Brien, Katherine L, Park, Daniel E, PERCH Study Group, Prosperi, Christine, Scott, J Anthony G, Seidenberg, Phil, Siludjai, Duangkamon, Sow, Samba O, Tamboura, Boubou, Thea, Donald M, Watson, Nora L, Zeger, Scott L   +37 more
core   +1 more source

Streptococcus pneumoniae HtrA is a dynamic and monomeric virulence factor capable of forming larger oligomeric complexes

Protein Science, Volume 35, Issue 1, January 2026.
Abstract High‐temperature requirement A (HtrA) proteases are a conserved family of serine proteases central to protein quality control and bacterial virulence. While Gram‐negative and human HtrAs are structurally well studied, Gram‐positive homologs remain essentially uncharacterized.
Eunjeong Lee, Jasmina S. Redzic, Blaine Gordon, Anthony J. Saviola, Norman Tran, Sean P. Maroney, Nathanael L. Ashby, Steven Shaw, Sam Fulte, Arianna McCarty, Todd Holyoak, Nancy Meyer, Kirk C. Hansen, Sarah E. Clark, Elan Eisenmesser   +14 more
wiley   +1 more source

Monocytes regulate the mechanism of T-cell death by inducing Fas-mediated apoptosis during bacterial infection. [PDF]

, 2012
Monocytes and T-cells are critical to the host response to acute bacterial infection but monocytes are primarily viewed as amplifying the inflammatory signal.
A Kadioglu, A Kadioglu, A Nalbant, A Strasser, AD Badley, Andrea M. Mitchell, C Riccardi, CA Janeway Jr, CK Sung, D Zhou, David H. Dockrell, DH Dockrell, DH Dockrell, DH Dockrell, DR Cundell, EE McGrath, FK Swirski, Frank R. DeLeo, G Matute-Bello, Helen M. Marriott, HM Marriott, HM Marriott, I Nicoletti, J Warwick-Davies, JA Carrero, Julie A. Preston, K Beiter, K Kemp, K LeMessurier, KA Browne, KE Price, L Galluzzi, L Maggi, L Ziegler-Heitbrock, LA Kirkham, M Daigneault, M Lenardo, M Witzenrath, MA Barocchi, MA Bewley, Marc Daigneault, Martin A. Bewley, MJ Jedrzejas, Moira K. B. Whyte, N Olivares-Zavaleta, N Oyaizu, NV Serbina, PA Kiener, R Malley, RA Hirst, Robert C. Read, RS Hotchkiss, RS Hotchkiss, RS Hotchkiss, SE Weber, SJ Webster, SL Newman, T Mattern, T Takahashi, Thushan I. De Silva, Timothy J. Mitchell, WL Farrar, WP Hausdorff, YJ Lu, Z Zhang   +64 more
core   +4 more sources

Reconsidering the Role of Blood Cultures in Community‐Acquired Pneumonia: A Case of Co‐Infection With Streptococcus pneumoniae and Klebsiella variicola

Respirology Case Reports, Volume 14, Issue 1, January 2026.
We report a case of community‐acquired pneumonia. In this case, the blood culture was essential for detection of co‐infection of Streptococcus pneumoniae and Klebsiella variicola, which combination is first reported. ABSTRACT Community‐acquired pneumonia (CAP) remains a leading cause of morbidity and mortality.
Naoki Fujimoto, Issei Oi, Kohei Fujita, Saiki Yoshimura, Takanori Ito, Takuma Imakita, Osamu Kanai, Kiminobu Tanizawa   +7 more
wiley   +1 more source

Primary Antibody Deficiency in Patients With Chronic Rhinosinusitis: A Call for Immunologic Evaluation Prior to Biologic Therapy

Clinical Otolaryngology, Volume 51, Issue 1, Page 144-152, January 2026.
ABSTRACT Objective Chronic rhinosinusitis (CRS) is prevalent and causes a great negative impact on quality of life. Primary antibody deficiency (PAD) is highly prevalent with CRS compared to the background population. There are efficient treatment options to consider when CRS is a symptom of PAD. The condition seems to be underdiagnosed.
Anita García Petersen, Kasra Zainali‐Gill, Carsten Schade Larsen, Christian Nielsen, Therese Ovesen   +4 more
wiley   +1 more source

Acquisition of pneumococci specific effector and regulatory Cd4+ T cells localising within human upper respiratory-tract mucosal lymphoid tissue [PDF]

, 2011
The upper respiratory tract mucosa is the location for commensal Streptococcus (S.) pneumoniae colonization and therefore represents a major site of contact between host and bacteria.
AD Reynolds, AM Faria, C Jokinen, C Laine, C O'Mahony, Carlos Javier Orihuela, D Bogaert, DM Musher, EJ Novak, EK Mulholland, EM Laughlin, G Oldenhove, H Christensen, HM Foy, HW Lim, I Rudan, JC Paton, Jeffrey Pido-Lopez, JL Round, JN Stoop, K Wing, KA Robinson, L Strauss, L Weiss, M Hara, M Hussain, M Lipsitch, M Livingston, M Quigley, MJ Butte, MJ van Kempen, MW Mureithi, N Iikuni, Neil A. Williams, PC Hill, PR Myles, Q Zhang, Q Zhang, Q Zhang, R Austrian, R Malley, R Malley, RM Wong, Robert S. Heyderman, S Hori, S Paust, S Rapola, S Read, S Sakaguchi, S Sakaguchi, SE Sandner, SK Obaro, SQ Crome, T Sturniolo, T Takahashi, Timothy J. Mitchell, V Davenport, William W. Kwok, X Zhang, Y Belkaid, Y Cong, YJ Lu, Z Zhang   +62 more
core   +3 more sources

Major revision version 13.0 of the European AIDS Clinical Society guidelines 2025

HIV Medicine, Volume 27, Issue 1, Page 18-32, January 2026.
Abstract Background The European AIDS Clinical Society (EACS) guidelines were revised for the 21st time in 2025, with updates covering all aspects of HIV care. Key Points of the Guidelines Update The structure of the guidelines has been reorganized into two parts: Part I focuses on the management and prevention of HIV and related infections, and Part ...
Juan Ambrosioni, Laura I. Levi, Jasmini Alagaratnam, Abiu Sempere, Andrea Mastrangelo, Paolo Paioni, Cristina Mussini, Catia Marzolini, Susanne Dam Nielsen, Charles Béguelin, Steven Welch, Anna Koval, Luis Mendao, Alasdair Bamford, Alexandra Calmy, Giovanni Guaraldi, Cristiana Oprea, Esteban Martínez, Jürgen K. Rockstroh, The EACS Governing Board   +19 more
wiley   +1 more source

Btk inhibitor ibrutinib reduces inflammatory myeloid cell responses in the lung during murine pneumococcal pneumonia

Molecular Medicine, 2019
Background Streptococcus pneumoniae is a major causative agent in community-acquired pneumonia and sepsis. Overwhelming lung inflammation during pneumococcal pneumonia may hamper lung function.
Alexander P. de Porto, Zhe Liu, Regina de Beer, Sandrine Florquin, Onno J. de Boer, Rudi W. Hendriks, Tom van der Poll, Alex F. de Vos   +7 more
doaj   +1 more source