Results 61 to 70 of about 383,894 (265)

Stewardship of Molecular Diagnostics in Transplant Viral Infections

Transplant Infectious Disease, EarlyView.
ABSTRACT The transplant environment requires special considerations when testing for viral infections as immunosuppression results in atypical infection profiles. Microbes otherwise considered commensals or causing mild disease can lead to severe infections in transplant environments. Therefore, guidelines tend to recommend broader microbial testing in
Scott Sugden, David Reynoso, Reema Mathew, Michael Loeffelholz   +3 more
wiley   +1 more source

Pneumococcal pneumonia prevalence among adults with severe acute respiratory illness in Thailand - comparison of Bayesian latent class modeling and conventional analysis

BMC Infectious Diseases, 2019
Background Determining the etiology of pneumonia is essential to guide public health interventions. Diagnostic test results, including from polymerase chain reaction (PCR) assays of upper respiratory tract specimens, have been used to estimate prevalence
Ying Lu, Lawrence Joseph, Patrick Bélisle, Pongpun Sawatwong, Anchalee Jatapai, Toni Whistler, Somsak Thamthitiwat, Wantana Paveenkittiporn, Supphacoke Khemla, Chris A. Van Beneden, Henry C. Baggett, Christopher J. Gregory   +11 more
doaj   +1 more source

Serotypes in Adult Pneumococcal Pneumonia in Spain in the Era of Conjugate Vaccines [PDF]

, 2021
Lucía Fernández-Delgado, Jordi Cámara, Aída González-Díaz, Inmaculada Grau, Hisashi Shoji, Fé Tubau, Sara Martí, M.Á. Domínguez, Jordi Carratalà, José Yuste, Carmen Ardanuy   +10 more
openalex   +1 more source

Infections in Chronic Lymphocytic Leukemia: Evolving Risks and Prevention Strategies

European Journal of Haematology, Volume 116, Issue 3, Page 204-214, March 2026.
ABSTRACT Infections remain a leading cause of morbidity and mortality in patients with chronic lymphocytic leukemia (CLL), reflecting both intrinsic immune dysfunction and therapy‐related immunosuppression. The pathogenesis of immunodeficiency in CLL is multifactorial: neoplastic B cells impair humoral immunity, T cells are functionally exhausted, and ...
Enrica Antonia Martino, Santino Caserta, Ernesto Vigna, Antonella Bruzzese, Nicola Amodio, Eugenio Lucia, Virginia Olivito, Caterina Labanca, Francesco Mendicino, Fortunato Morabito, Massimo Gentile   +10 more
wiley   +1 more source

Retrospective database analysis for clinical diagnoses commonly associated with pneumococcal diseases in the Malaysian healthcare system over a 3-year period (2013–2015)

BMC Infectious Diseases
Background Pneumococcal disease caused by Streptococcus pneumoniae is an important cause of morbidity and mortality across all ages, particularly in younger children and older adults. Here, we describe pneumococcal disease hospitalizations at Ministry of
Saravanan S. R. Sundaramurthy, Kristen E. Allen, Mark A. Fletcher, Kok Fui Liew, Boekhtiar Borhanuddin, Mohammad Ali, Graciela Morales, Bradford Gessner, Jerusha Naidoo, Jo Southern   +9 more
doaj   +1 more source

Herd effects of child vaccination with pneumococcal conjugate vaccine against pneumococcal non-invasive community-acquired pneumonia: What is the evidence?

Human Vaccines & Immunotherapeutics, 2017
Quantification of pneumococcal conjugate vaccines (PCVs) herd effects are mainly performed on invasive pneumococcal disease (IPD) but there is conflicting evidence regarding herd effects of PCVs on non-IPD pneumococcal community-acquired pneumonia.
Cornelis H. van Werkhoven
doaj   +1 more source

Evaluation of Pneumococcal Load in Blood by Polymerase Chain Reaction for the Diagnosis of Pneumococcal Pneumonia in Young Children in the PERCH Study

Clinical Infectious Diseases, 2017
Background. Detection of pneumococcus by lytA polymerase chain reaction (PCR) in blood had poor diagnostic accuracy for diagnosing pneumococcal pneumonia in children in 9 African and Asian sites.
M. Deloria Knoll, Susan C. Morpeth, J. Scott, Nora L. Watson, Daniel E Park, H. Baggett, W. A. Brooks, D. Feikin, L. Hammitt, S. Howie, K. Kotloff, O. Levine, K. O'Brien, D. Thea, D. Ahmed, M. Antonio, J. Awori, V. Baillie, J. Chipeta, A. DeLuca, M. Dione, A. Driscoll, Melissa M Higdon, Anchalee Jatapai, R. Karron, Razib Mazumder, D. Moore, J. Mwansa, S. Nyongesa, Christine Prosperi, P. Seidenberg, D. Siludjai, S. Sow, Boubou Tamboura, S. Zeger, D. Murdoch, S. Madhi, Katherine L. Orin S. Maria Deloria Daniel R. Andrea N. Amand O’Brien Levine Knoll Feikin DeLuca Driscoll Fancou, K. O'Brien, O. Levine, M. Knoll, D. Feikin, A. DeLuca, A. Driscoll, N. Fancourt, W. Fu, L. Hammitt, Melissa M Higdon, E. Kagucia, R. Karron, Mengying Li, Daniel E Park, Christine Prosperi, Zhenke Wu, S. Zeger, Nora L. Watson, Jane Crawley, D. Murdoch, W. A. Brooks, H. Endtz, K. Zaman, D. Goswami, L. Hossain, Y. Jahan, H. Ashraf, S. Howie, B. Ebruke, M. Antonio, J. McLellan, E. Machuka, Arifin Shamsul, Syed M. A. Zaman, G. Mackenzie, J. Scott, J. Awori, Susan C. Morpeth, A. Kamau, S. Kazungu, M. Ominde, K. Kotloff, Milagritos D. Tapia, S. Sow, M. Sylla, Boubou Tamboura, U. Onwuchekwa, N. Kourouma, A. Touré, S. Madhi, D. Moore, P. Adrian, V. Baillie, Locadiah Kuwanda, Azwifarwi Mudau, M. Groome, N. Mahomed, H. Baggett, S. Thamthitiwat, S. Maloney, C. Bunthi, J. Rhodes, Pongpun Sawatwong, P. Akarasewi, D. Thea, L. Mwananyanda, J. Chipeta, P. Seidenberg, J. Mwansa, Somwe Wa Somwe, G. Kwenda, T. Anderson, Joanne L. Mitchell   +110 more
semanticscholar   +1 more source

Cardio–Renal Diseases Are Independent Risk Factors of Severe Human Metapneumovirus Infection Among Patients Without Chronic Airway Diseases

Journal of Medical Virology, Volume 98, Issue 2, February 2026.
ABSTRACT Human metapneumovirus (hMPV) causes mild and self‐limiting disease in adults. However, the risk factors for serious adverse outcomes following hMPV infection in adult patients without preexisting chronic airway diseases remain poorly understood.
Wang Chun Kwok, Isaac Sze Him Leung, Chun Ka Emmanuel Wong, James Chung Man Ho, David Chi Leung Lam, Mary Sau Man Ip, Shuk Man Ngai, Kelvin Kai Wang To, Desmond Yat Hin Yap   +8 more
wiley   +1 more source

Vasculotide reduces pulmonary hyperpermeability in experimental pneumococcal pneumonia

Critical Care, 2017
BackgroundCommunity-acquired pneumonia (CAP) is a significant cause of morbidity and mortality worldwide. Despite effective antimicrobial therapy, CAP can induce pulmonary endothelial hyperpermeability resulting in life-threatening lung failure due to an
B. Gutbier, Xiaohui Jiang, K. Dietert, C. Ehrler, J. Lienau, P. van Slyke, Harold Kim, V. Hoang, J. Maynes, D. Dumont, A. Gruber, N. Weissmann, T. Mitchell, N. Suttorp, M. Witzenrath   +14 more
semanticscholar   +1 more source

A Retrospective Study of Pneumococcal Pneumonia in Hospitalized Patients Aged ≥65 Years in Izumo, Japan: 2010 to 2014

International Journal of General Medicine, 2023
Megumi Hamaguchi,1 Yukari Tsubata,1 Ken Yoshihara,1 Mika Nakao,1 Yoshihiro Amano,1 Kazuhisa Nakashima,1 Takamasa Hotta,2 Tamio Okimoto,1 Shunichi Hamaguchi,3 Akihisa Sutani,4 Takeshi Isobe1 1Division of Medical Oncology and Respiratory Medicine ...
Hamaguchi M, Tsubata Y, Yoshihara K, Nakao M, Amano Y, Nakashima K, Hotta T, Okimoto T, Hamaguchi S, Sutani A, Isobe T   +10 more
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