Results 51 to 60 of about 29,982 (175)
ABSTRACT Sutimlimab is a monoclonal antibody against complement fraction C1s approved for the treatment of hemolytic anemia due to cold agglutinin disease (CAD). Here, we analyzed and report the largest international CAD cohort of sutimlimab‐treated patients ever reported to highlight its safety and effectiveness in the real‐world setting. We accrued a
Bruno Fattizzo +38 more
wiley +1 more source
ABSTRACT Background and Aim Pneumonia contributes substantially to the childhood mortality burden in low and middle‐income countries (LMICs). Reported predictors of mortality in childhood pneumonia in LMIC are varied. This study aimed to describe predictors of mortality among children with pneumonia in a tertiary hospital in Ghana.
Sandra Kwarteng Owusu +17 more
wiley +1 more source
ABSTRACT Background Pneumococcus are often found in the respiratory tract of healthy people, especially children, and are a common cause of infections such as otitis media, sinusitis, conjunctivitis and community‐acquired pneumonia. In other cases, the bacteria can cause more serious conditions known collectively as invasive pneumococcal disease (IPD),
Pamela Di Giovanni +9 more
wiley +1 more source
Are the pneumococcal polysaccharide vaccines effective? Meta-analysis of the prospective trials
The objective was to review the evidence of effectiveness of the polyvalent polysaccharide pneumococcal vaccine from prospective properly randomised controlled trials comparing pneumococcal vaccines with placebo in subjects who are immunocompetent and ...
Lipsky Benjamin A +2 more
doaj +1 more source
Pyroptosis maintains immune homeostasis by eliminating damaged or infected cells, but its dysregulation promotes inflammation and cancer progression. The diagram illustrates key activation pathways, links with other programmed cell deaths, and cancer‐specific effects, enhancing its dual protective and pathogenic roles.
Diego Liviu Boaru +18 more
wiley +1 more source
Fulminating pneumococcal septicemia without an obvious focus of infection is very rare in previously immunocompetent children older than two years. Furthermore, pneumatocele formation in pneumococcal pneumonia is uncommon.
Y Aslan +4 more
doaj
BackgroundThe importance of bacterial infections following respiratory syncytial virus (RSV) remains unclear. We evaluated whether variations in RSV epidemic timing and magnitude are associated with variations in pneumococcal disease epidemics and ...
Daniel M Weinberger +4 more
doaj +1 more source
BackgroundS. pneumoniae is a leading cause of meningitis morbidity and mortality in the African meningitis belt, but little is known of its contribution to the burden of pneumonia in the region.
Jennifer C Moïsi +8 more
doaj +1 more source

