Results 51 to 60 of about 31,112 (177)

Dispensing Patterns of Influenza and Pneumococcal Vaccines in the Private Healthcare Sector in South Africa for 2017 to 2021: A Longitudinal Study

open access: yesPharmacoepidemiology and Drug Safety, Volume 35, Issue 10, October 2026.
ABSTRACT Purpose The primary aim was to conduct a longitudinal pharmacoepidemiological study on the dispensing patterns of the influenza and pneumococcal vaccines in a section of the private healthcare sector in South Africa in the presence of the COVID‐19 vaccine to document the dispensing of these two respiratory vaccines alongside COVID‐19 vaccines.
I. Truter   +4 more
wiley   +1 more source

Updates in COPD Management: From Inflammatory Pathways to Targeted Therapies

open access: yesEuropean Journal of Clinical Investigation, Volume 56, Issue 10, October 2026.
COPD is a heterogeneous disease driven by overlapping neutrophilic and eosinophilic inflammatory pathways. This review highlights the shift from symptom‐based treatment toward phenotype‐ and biomarker‐directed care. Blood eosinophils, FeNO, and IgE predict corticosteroid responsiveness and identify candidates for biologic therapy.
Sasha Raman   +3 more
wiley   +1 more source

Are the pneumococcal polysaccharide vaccines effective? Meta-analysis of the prospective trials

open access: yesBMC Family Practice, 2000
The objective was to review the evidence of effectiveness of the polyvalent polysaccharide pneumococcal vaccine from prospective properly randomised controlled trials comparing pneumococcal vaccines with placebo in subjects who are immunocompetent and ...
Lipsky Benjamin A   +2 more
doaj   +1 more source

Risk Factors of Blood Culture Positivity and Mortality in Bloodstream Infections: A Population‐Based Study of Patients With B‐Cell Malignancies

open access: yesEuropean Journal of Haematology, Volume 117, Issue 4, Page 1061-1071, October 2026.
ABSTRACT Background Bloodstream infections remain a major cause of mortality among cancer patients. Pathogen surveillance and risk stratification tools are key to improved management. This study describes trends in causative pathogens and explores risk factors for positive blood cultures (PBCs) and post‐infection mortality in cancer patients.
Mathias Holmsgaard Eskesen   +7 more
wiley   +1 more source

Occult pneumococcal septicemia and pneumococcal pneumonia complicating pneumatoceles in a previously healthy child

open access: yesThe Turkish Journal of Pediatrics, 1998
Fulminating pneumococcal septicemia without an obvious focus of infection is very rare in previously immunocompetent children older than two years. Furthermore, pneumatocele formation in pneumococcal pneumonia is uncommon.
Y Aslan   +4 more
doaj  

Association between respiratory syncytial virus activity and pneumococcal disease in infants: a time series analysis of US hospitalization data.

open access: yesPLoS Medicine, 2015
BackgroundThe importance of bacterial infections following respiratory syncytial virus (RSV) remains unclear. We evaluated whether variations in RSV epidemic timing and magnitude are associated with variations in pneumococcal disease epidemics and ...
Daniel M Weinberger   +4 more
doaj   +1 more source

A Machine Learning–Derived Risk Scorecard for Pneumonia Hospitalization in Japanese Old‐Old Adults

open access: yesGeriatrics &Gerontology International, Volume 26, Issue 10, October 2026.
In 1 098 404 community‐dwelling Japanese adults aged ≥ 75 years, a 20‐learner Super Learner using routinely collected health checkup and claims data predicted 1‐year pneumonia hospitalization (test‐set AUC 0.823). An independently developed, well‐calibrated 17‐feature scorecard showed AUC 0.786 and a 15.9‐fold low‐to‐high risk gradient; external ...
Akio Shimizu   +5 more
wiley   +1 more source

Serotypes and antibiotic susceptibility of isolated from hospitalized patients with community-acquired pneumonia in Italy

open access: yesSAGE Open Medicine, 2017
Background: Pneumonia remain an important public health problem. The primary objective was to determine the proportion of community-acquired pneumonia that is attributable to Streptococcus pneumoniae infection; secondary objectives were the description ...
Marta Di Pasquale   +6 more
doaj   +1 more source

Burden of Pneumococcal Disease in Northern Togo before the Introduction of Pneumococcal Conjugate Vaccine.

open access: yesPLoS ONE, 2017
BackgroundS. pneumoniae is a leading cause of meningitis morbidity and mortality in the African meningitis belt, but little is known of its contribution to the burden of pneumonia in the region.
Jennifer C Moïsi   +8 more
doaj   +1 more source

Using Synthetic Glycans to Investigate Anti‐Glycan Antibodies and Explore Their Medical Potential

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 39, 21 September 2026.
Anti‐glycan antibodies are essential in health and disease. Access to novel glycan structures paves the way for progress in antibody profiling for biomarker discovery, antibody development, and vaccine design. We summarize the strategies to synthesize and utilize synthetic glycans for the development and application of anti‐glycan antibodies in basic ...
Fabienne Weber   +4 more
wiley   +1 more source

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