Results 71 to 80 of about 622,361 (248)
Towards New Broader Spectrum Pneumococcal Vaccines: The Future of Pneumococcal Disease Prevention
Vaccines, 2014 Seven-valent pneumococcal conjugate vaccine (PCV7) introduction and routine pediatric use has substantially reduced the burden of Streptococcus pneumoniae disease worldwide.
Lucia H. Lee, X. Gu, M. Nahm
semanticscholar +1 more source
Flagellins as Vaccine Adjuvants and Cancer Immunotherapy: Recent Advances and Future Prospects
Immunology, EarlyView.The figure depicts the role of flagellin in immune cells. Flagellin interacts with TLR5, resulting in the formation of homodimers and the recruitment of MyD88, which activates the IκB and MAPK signalling pathways. This results in the activation of NF‐κB and AP‐1, producing TNF‐α, IL‐6, IL‐8, and IL‐12.
Asma Talukder +4 more
wiley +1 more source
Tissue Resident Memory Cells: Friend or Foe?
Immunology, EarlyView.Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude +2 more
wiley +1 more source
Вопросы современной педиатрии, 2009 This article presents the review of results of International conference on pneumococcal conjugated vaccines. Main results of international experience in the field of control of pneumococcal infection spreading are analyzed. Authors present modern data of
M.V. Fedoseenko, L.S. Namazova-Baranova
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Frontiers in Immunology, 2019 Streptococcus pneumoniae is the most common respiratory bacterial pathogen among cases of community-acquired infection in young children, older adults, and individuals with underlying medical conditions.
A-Yeung Jang +15 more
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Systemic treatment of immune checkpoint inhibitor‐induced psoriasis: Inference‐based guidance
Journal of the European Academy of Dermatology and Venereology, EarlyView.When managing psoriasis, induced or exacerbated by ICI therapy for cancer, there are concerns regarding immunosuppression from systemic agents for the treatment of psoriasis and the potential impact on ICI efficacy. No direct, high‐level evidence exists to address these concerns.
Kim A. Papp +14 more
wiley +1 more source
Journal of the American Geriatrics Society, EarlyView.ABSTRACT Background Recent studies suggest that respiratory syncytial virus (RSV) can cause severe illness in terms of in‐hospital outcomes and mortality. The degree to which RSV hospitalization is associated with cardiovascular outcomes, particularly those known to occur following acute respiratory infections, is poorly described. Methods We conducted
Chris P. Verschoor +6 more
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Journal of the American Geriatrics Society, EarlyView.ABSTRACT Background Respiratory syncytial virus (RSV) is a common cause of acute respiratory illness and can lead to serious morbidity and mortality in older adults. With the Food and Drug Administration approval and the Centers for Disease Control and Prevention (CDC) recommendation of RSV vaccines in 2023, this study describes first season vaccine ...
Austin Murphy +7 more
wiley +1 more source
Safety and Efficacy of Pneumococcal Vaccination in Pediatric Nephrotic Syndrome
Frontiers in Pediatrics, 2019 Nephrotic syndrome affects both children and adults. Idiopathic nephrotic syndrome is reported to be one of the most frequent renal pathologies in childhood.
Shamitha Thishakya Goonewardene +16 more
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Clinical Infectious Diseases, 2016 BACKGROUND Pneumococcal conjugated vaccines (PCVs) impact on complex otitis media (OM; including recurrent, nonresponsive, and chronic OM with effusion) was greater than that on simple, acute OM in previous studies.
S. Ben-Shimol +5 more
semanticscholar +1 more source