Results 51 to 60 of about 31,481 (258)

Adjunctive Corticosteroid Therapy Decreases Lung Permeability in Patients with AIDS-Related Pneumocystis carinii Pneumonia

Canadian Respiratory Journal, 1995
OBJECTIVE: To assess the effect of adjunctive corticosteroid therapy on lung permeability as measured by Tc-DTPA lung clearance scan in patients with AIDS-related Pneumocystis carinii pneumonia (PCP).
Silvia Guillemi, Allan Belzberg, Lindsay M Lawson, Martin T Schechter, Julio SG Montaner   +4 more
doaj   +1 more source

Genetic Variation in Pneumocystis carinii Isolates from Different Geographic Regions: Implications for Transmission

Emerging Infectious Diseases, 2000
To study transmission patterns of Pneumocystis carinii pneumonia (PCP) in persons with AIDS, we evaluated P. carinii isolates from patients in five U.S.
Charles B. Beard, Jane L. Carter, Scott P. Keely, Laurence Huang, Norman J. Pieniazek, Iaci N.S. Moura, Jacquelin M. Roberts, Allen W. Hightower, Michelle S. Bens, Amanda R. Freeman, Sherline Lee, James R. Stringer, Jeffrey S. Duchin, Carlos Del Rio, David Rimland, Robert P. Baughman, Deborah A. Levy, Vance J. Dietz, Paul Simon, Thomas R. Navin   +19 more
doaj   +1 more source

Anti-Pneumocystis carinii and antiplasmodial activities of primaquine-derived imidazolidin-4-ones [PDF]

, 2008
A series of primaquine-derived imidazolidin-4-ones were screened for their in vitro activity against Pneumocystis carinii and Plasmodium falciparum W2 strain. Most compounds were active against P.
Jiri Gut, Margaret S Collins, Melanie T Cushionc, Nuno Vale, Paula Gomes, Philip J Rosenthal, Ricardo Ferraz, Rui Moreira   +7 more
core   +1 more source

Caspofungin Combined With TMP/SMZ in Treatment of Intractable Acute Pneumocystis jirovecii Pneumonia in Renal Transplant Recipients: Case Report and Literature Review

Clinical Case Reports, Volume 13, Issue 8, August 2025.
ABSTRACT Pneumocystis jirovecii pneumonia (PJP) is a potential life‐threatening opportunistic infection that predominantly affects immunocompromised individuals, such as those with human immunodeficiency virus or organ transplant recipients. The treatment of PJP, particularly severe cases, remains challenging, as standardized treatment therapies often ...
Hongtao Hu, Shen Xu, Wen Jiang, Baoping Xu, Jing Wang, Gang Xu   +5 more
wiley   +1 more source

A New Name for Pneumocystis from Humans and New Perspectives on the Host-Pathogen Relationship

Emerging Infectious Diseases, 2002
The disease known as Pneumocystis carinii pneumonia (PCP) is a major cause of illness and death in persons with impaired immune systems. While the genus Pneumocystis has been known to science for nearly a century, understanding of its members remained ...
James R. Stringer, Charles B. Beard, Robert F. Miller, Ann E. Wakefield   +3 more
doaj   +1 more source

Transcriptome of Pneumocystis carinii during fulminate infection: carbohydrate metabolism and the concept of a compatible parasite. [PDF]

PLoS ONE, 2007
Members of the genus Pneumocystis are fungal pathogens that cause pneumonia in a wide variety of mammals with debilitated immune systems. Little is known about their basic biological functions, including life cycle, since no species can be cultured ...
Melanie T Cushion, A George Smulian, Bradley E Slaven, Tom Sesterhenn, Jonathan Arnold, Chuck Staben, Aleksey Porollo, Rafal Adamczak, Jarek Meller   +8 more
doaj   +1 more source

Safety Evaluation of Serendipity Berry Sweet Protein From Komagataella phaffii

Journal of Applied Toxicology, Volume 45, Issue 8, Page 1455-1475, August 2025.
ABSTRACT Serendipity Berry Sweet Protein (sweelin) is a novel hyper‐sweet thermophilic protein designed using Artificial Intelligence Computational Protein Design (AI‐CPD) to improve the stability and sensory profile of the protein found in serendipity berry (Dioscoreophyllum cumminsii).
Yael Lifshitz, Shira Paz, Rotem Saban, Inbar Zuker, Hagay Shmuely, Katy Gorshkov, Jwar Meetro, Shahrzad Tafazoli, Trung Vo, Gabriela Amiram, Carmit Shani Levi, Uri Lesmes, Ilan Samish   +12 more
wiley   +1 more source

Cooperative Stimulation of Dendritic Cells by Cryptococcus neoformans Mannoproteins and CpG Oligodeoxynucleotides [PDF]

, 2008
While mannosylation targets antigens to mannose receptors on dendritic cells (DC), the resultant immune response is suboptimal. We hypothesized that the addition of toll-like receptor (TLR) ligands would enhance the DC response to mannosylated antigens ...
Dan, Jennifer M., Lee, Chrono K., Levitz, Stuart M., Wang, Jennifer P.   +3 more
core   +4 more sources

Association of Pulmonary Septic Embolism and Pulmonary Arterial Thromboembolism in Lemierre Syndrome: A Case Report and Literature Review

Respirology Case Reports, Volume 13, Issue 7, July 2025.
We report a rare presentation of Lemierre's syndrome in a 65‐year‐old woman, characterised by the coexistence of septic pulmonary emboli and pulmonary arterial thromboembolism, both documented on CT pulmonary angiography. ABSTRACT Lemierre syndrome (LS) is a rapidly progressing disease characterised by a recent oropharyngeal infection, complicated by ...
Antonio Fabozzi, Alessandro Siena, Alessia Steffanina, Silvia Iannuzzi, Matteo Bonini, Paolo Palange   +5 more
wiley   +1 more source

The UK Infected Blood Inquiry: A Personal Reflection

Haemophilia, Volume 31, Issue 4, Page 601-606, July 2025.
ABSTRACT The UK Infected Blood Inquiry (IBI) considered the transfusion transmitted infections hepatitis B and C, HIV, and vCJD. The inquiry lasted 6 years during 2018 to 2024 and reported to the UK parliament on 20 May, 2024. It concluded that at least 3000 people died because of the recklessness and obstinacy of officialdom and it has been reported ...
Christine A. Lee
wiley   +1 more source