Scaling-up co-trimoxazole prophylaxis in HIV-exposed and HIV-infected children in high HIV-prevalence countries. [PDF]
, 2007 Co-trimoxazole (trimethoprim-sulfamethoxazole) is a widely available antibiotic that substantially reduces HIV-related morbidity and mortality in both adults and children.
Abdel-Haq +33 more
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BMC Infectious Diseases, 2019 Background Pneumocystis jirovecii pneumonia (PCP) is one of the most common HIV-related opportunistic infections. The diagnosis of PCP is based on analyses from respiratory tract specimens which may require the invasive procedure of a diagnostic ...
Helena Hammarström +6 more
doaj +1 more source
Functional characterization of the Pneumocystis jirovecii potential drug targets dhfs and abz2 involved in folate biosynthesis. [PDF]
, 2015 Pneumocystis species are fungal parasites colonizing mammal lungs with strict host specificity. Pneumocystis jirovecii is the human-specific species and can turn into an opportunistic pathogen causing severe pneumonia in immunocompromised individuals ...
Cissé, O.H. +4 more
core +1 more source
Consensus definitions of 14 severe acute toxic effects for childhood lymphoblastic leukaemia treatment: a Delphi consensus [PDF]
, 2016 Although there are high survival rates for children with acute lymphoblastic leukaemia, their outcome is often counterbalanced by the burden of toxic effects.
Attarbaschi, Andishe +20 more
core +2 more sources
Acta Médica Portuguesa, 2016 Introdução: A pneumonia por Pneumocystis jirovecii é das doenças infecciosas oportunistas mais comuns em infectados por vírus da imunodeficiência humana, sendo, actualmente, em Portugal a infecção definidora de sida mais reportada.
Vilma Grilo, Aida Pereira
doaj +1 more source
AIDS-defining illnesses at initial diagnosis of HIV in a large Guatemalan cohort [PDF]
, 2017 BackgroundAnecdotal evidence suggests that a high proportion of patients diagnosed with HIV in Guatemala present with AIDS. There remain limited data on the epidemiology of AIDS-defining illnesses (ADIs) in Central America.MethodsWe conducted a ...
Cordon, Andrea Alonzo +6 more
core +2 more sources
Comparative genomics suggests that the human pathogenic fungus Pneumocystis jirovecii acquired obligate biotrophy through gene loss. [PDF]
, 2014 Pneumocystis jirovecii is a fungal parasite that colonizes specifically humans and turns into an opportunistic pathogen in immunodeficient individuals. The fungus is able to reproduce extracellularly in host lungs without eliciting massive cellular death.
Cissé, O.H., Hauser, P.M., Pagni, M.
core +1 more source
Diagnosis and management of Pneumocystis jirovecii infection [PDF]
, 2017 Introduction: Pneumocystis jirovecii is a ubiquitous fungus, which causes pneumonia in humans. Diagnosis was hampered by the inability to culture the organism, and based on microscopic examination of respiratory samples or clinical presentation.
Backx, Matthijs +2 more
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Unusual Radiographic Presentation of Pneumocystis Pneumonia in a Patient with AIDS. [PDF]
, 2017 Pneumocystis jirovecii pneumonia (PCP) typically presents as an interstitial and alveolar process with ground glass opacities on chest computed tomography (CT).
Block, Brian L +6 more
core +3 more sources
P neumocystis jirovecii pneumonia is rare in renal transplant recipients receiving only one month of prophylaxis [PDF]
, 2011 Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/89470/1/tid692 ...
Arend +21 more
core +1 more source