Case Report: Successful treatment of severe pneumocystis carinii pneumonia in a case series of primary nephrotic syndrome after receiving anti-CD20 monoclonal antibody therapy [PDF]
Frontiers in Pediatrics, 2023 Rituximab is emerging as a new steroid sparing agent in children with difficult-to-treat nephrotic syndrome due to its ability of depleting CD20-positive B cells.
Lili Liu +8 more
doaj +2 more sources
Immunization with Pneumocystis carinii A121–85 antigen activates immune function against P. carinii [PDF]
BMC Immunology, 2021 Background Pneumocystis pneumonia (PcP), which is caused by Pneumocystis carinii, is a life-threatening infection that affects immunocompromised individuals. Unfortunately, chemoprophylaxis and dapsone are only effective for half of the patients with PcP,
Tong Tong +3 more
doaj +2 more sources
Extracellular vesicles from Pneumocystis carinii-infected rats impair fungal viability but are dispensable for macrophage functions [PDF]
Microbiology SpectrumPneumocystis spp. are host obligate fungal pathogens that can cause severe pneumonia in mammals and rely heavily on their host for essential nutrients. The lack of a sustainable in vitro culture system poses challenges in understanding their metabolism ...
Steven G. Sayson +2 more
doaj +2 more sources
Functional Characterization of
mBio, 2016 Fungi in the genus Pneumocystis live in the lungs of mammals, where they can cause a fatal pneumonia (PCP [Pneumocystis pneumonia]) in hosts with compromised immune systems.
Melanie T. Cushion +5 more
doaj +2 more sources
Nested–polymerase chain reaction detection of f. sp. in a suspected immunocompromised Cavalier King Charles spaniel with multiple infections [PDF]
SAGE Open Medical Case Reports, 2019 A 7-month-old Cavalier King Charles Spaniel female was referred due to a chronic cough refractory to antibiotic treatments. Laboratory findings showed leukocytosis, increased serum C-reactive protein, hypogammaglobulinemia, and decreased total serum ...
Matteo Petini +3 more
doaj +2 more sources
Case Report: Pneumocystis jiroveci pneumonia: report of five children with the nephrotic syndrome and review of the literature [PDF]
Frontiers in PediatricsObjectiveTo retrospectively analyze the clinical characteristics, treatment, and prognosis of five pediatric patients with nephrotic syndrome who developed Pneumocystis carinii pneumonia (PJP) after long-term use of steroids and tacrolimus.MethodsA ...
Peitong Han +4 more
doaj +2 more sources
Evidence of airborne excretion of Pneumocystis carinii during infection in immunocompetent rats. Lung involvement and antibody response. [PDF]
PLoS ONE, 2013 To better understand the role of immunocompetent hosts in the diffusion of Pneumocystis in the environment, airborne shedding of Pneumocystis carinii in the surrounding air of experimentally infected Sprague Dawley rats was quantified by means of a real ...
Jean Menotti +8 more
doaj +1 more source
Nursing, 2002 Pneumocystis carinii is an atypical fungus that causes pneumonia in immunocompromised individuals. P. carinii comprises a heterogeneous group of organisms that have been isolated from a wide range of mammalian host species. P. carinii infection is host species specific, the P. carinii organisms that infect humans have only been found in humans.
openaire +4 more sources
Scaling-up co-trimoxazole prophylaxis in HIV-exposed and HIV-infected children in high HIV-prevalence countries. [PDF]
, 2007 Co-trimoxazole (trimethoprim-sulfamethoxazole) is a widely available antibiotic that substantially reduces HIV-related morbidity and mortality in both adults and children.
Abdel-Haq +33 more
core +2 more sources