Results 21 to 30 of about 11,644 (153)

Sulfa Resistance and Dihydropteroate Synthase Mutants in Recurrent Pneumocystis carinii Pneumonia

open access: yesEmerging Infectious Diseases, 2003
Failure of sulfa or sulfone prophylaxis is associated with mutations in Pneumocystis carinii gene coding for dihydropteroate synthase (DHPS). The DHPS genotype was analyzed in AIDS patients who had two separate episodes of P. carinii pneumonia.
Aimable Nahimana   +6 more
doaj   +1 more source

Comparative genomics suggests that the fungal pathogen pneumocystis is an obligate parasite scavenging amino acids from its host's lungs. [PDF]

open access: yesPLoS ONE, 2010
Pneumocystis jirovecii is a fungus causing severe pneumonia in immuno-compromised patients. Progress in understanding its pathogenicity and epidemiology has been hampered by the lack of a long-term in vitro culture method.
Philippe M Hauser   +6 more
doaj   +1 more source

Aerosolised pentamidine for Pneumocystis carinii pneumonia in patients with acquired immunodeficiency syndrome Aerosol de pentamidina no tratamento da pneumonia por Pneumocystis carinii em pacientes com a síndrome da imunodeficiência adquirida

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 1990
The goal of this study was to evaluate inhaled pentamidine for the treatment of patients with mild and moderate Pneumocystis carinii pneumonitis. Eight adults with AIDS and pneumocystis pneumonia (4 with a first episode and 4 with a repeat pneumocystosis)
Adriana Weinberg   +5 more
doaj   +1 more source

Ploidy of cell-sorted trophic and cystic forms of Pneumocystis carinii.

open access: yesPLoS ONE, 2011
Once regarded as an AIDS-defining illness, Pneumocystis pneumonia (PcP) is nowadays prevailing in immunocompromised HIV-negative individuals such as patients receiving immunosuppressive therapies or affected by primary immunodeficiency.
Anna Martinez   +8 more
doaj   +1 more source

SYTO-13, a Viability Marker as a New Tool to Monitor In Vitro Pharmacodynamic Parameters of Anti-Pneumocystis Drugs.

open access: yesPLoS ONE, 2015
While Pneumocystis pneumonia (PcP) still impacts the AIDS patients, it has a growing importance in immunosuppressed HIV-negative patients. To determine the anti-Pneumocystis therapeutic efficacy of new compounds, animal and in vitro models have been ...
Annie Standaert-Vitse   +8 more
doaj   +1 more source

Basic biology of Pneumocystis carinii: a mini review

open access: yesMemorias do Instituto Oswaldo Cruz, 2005
Basic aspects of cell biology of Pneumocystis carinii are reviewed with major emphasis on its life cycle and the structural organization of the trophozoites and cyst forms.
Wanderley de Souza, Marlene Benchimol
doaj   +1 more source

Establishment and Preliminary Application of a Multiplex TaqMan Real-Time Fluorescence Quantitative PCR Assay for the Detection of Pneumocystis Species

open access: yesMicroorganisms
Pneumocystis is an opportunistic fungal pathogen that causes severe Pneumocystis pneumonia (PCP) in immunocompromised individuals and laboratory animals. Three host-specific species—Pneumocystis murina (P. murina), Pneumocystis carinii (P.
Qiuyang Sun   +5 more
doaj   +1 more source

Adjunctive Corticosteroid Therapy Decreases Lung Permeability in Patients with AIDS-Related Pneumocystis carinii Pneumonia

open access: yesCanadian Respiratory Journal, 1995
OBJECTIVE: To assess the effect of adjunctive corticosteroid therapy on lung permeability as measured by Tc-DTPA lung clearance scan in patients with AIDS-related Pneumocystis carinii pneumonia (PCP).
Silvia Guillemi   +4 more
doaj   +1 more source

A New Name for Pneumocystis from Humans and New Perspectives on the Host-Pathogen Relationship

open access: yesEmerging Infectious Diseases, 2002
The disease known as Pneumocystis carinii pneumonia (PCP) is a major cause of illness and death in persons with impaired immune systems. While the genus Pneumocystis has been known to science for nearly a century, understanding of its members remained ...
James R. Stringer   +3 more
doaj   +1 more source

Genetic Variation in Pneumocystis carinii Isolates from Different Geographic Regions: Implications for Transmission

open access: yesEmerging Infectious Diseases, 2000
To study transmission patterns of Pneumocystis carinii pneumonia (PCP) in persons with AIDS, we evaluated P. carinii isolates from patients in five U.S.
Charles B. Beard   +19 more
doaj   +1 more source

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