Results 21 to 30 of about 10,858 (172)

Sulfa Resistance and Dihydropteroate Synthase Mutants in Recurrent Pneumocystis carinii Pneumonia

Emerging Infectious Diseases, 2003
Failure of sulfa or sulfone prophylaxis is associated with mutations in Pneumocystis carinii gene coding for dihydropteroate synthase (DHPS). The DHPS genotype was analyzed in AIDS patients who had two separate episodes of P. carinii pneumonia.
Aimable Nahimana, Meja Rabodonirina, Jannik Helweg-Larsen, Isabelle Meneau, Patrick Francioli, Jacques Bille, Philippe M. Hauser   +6 more
doaj   +1 more source

Application of Microbial and Parasitology Techniques for Diagnosis in Laboratory Rodents

Current Protocols, Volume 6, Issue 7, July 2026.
Abstract Pathogen diagnosis in rodents through effective health monitoring programs is essential for maintaining high welfare and standards in laboratory animal facilities. Although many animal facilities are increasingly adopting real‐time polymerase chain reaction testing of environmental or filter samples for pathogen detection, thereby reducing the
Debora Rapaport, Maya Levin Arama, Michael Harlev   +2 more
wiley   +1 more source

Comparative genomics suggests that the fungal pathogen pneumocystis is an obligate parasite scavenging amino acids from its host's lungs. [PDF]

PLoS ONE, 2010
Pneumocystis jirovecii is a fungus causing severe pneumonia in immuno-compromised patients. Progress in understanding its pathogenicity and epidemiology has been hampered by the lack of a long-term in vitro culture method.
Philippe M Hauser, Frédéric X Burdet, Ousmane H Cissé, Laurent Keller, Patrick Taffé, Dominique Sanglard, Marco Pagni   +6 more
doaj   +1 more source

Oral Cryptococcosis due to Naganishia diffluens in a Patient With Thalassemia: A Case Report and a Literature Review

Journal of Clinical Laboratory Analysis, Volume 40, Issue 11, June 2026.
Naganishia diffluens, a rare non‐neoformans cryptococcal species, was identified by PCR sequencing as the causative agent of oral cryptococcosis in a 31‐year‐old Iranian man with β‐thalassemia. This case represents the first documented instance of oral infection by N.
Zahra Yahyazadeh, Zeynab Haseli, Javad Javidnia, Mahdi Abastabar, Eisa Nazar, Hosein Jalali, Mohamad Taghi Hedayati, Hossein Karami, Mohsen Nosratabadi, Lotfollah Davoodi, Seyyed Reza Aghili, Maryam Moazeni, Iman Haghani, Hamid Badali   +13 more
wiley   +1 more source

Severe HCoV‐OC43 Pneumonia in a 25‐Year‐Old Woman Following Allogeneic Hematopoietic Stem Cell Transplantation

The Clinical Respiratory Journal, Volume 20, Issue 5, May 2026.
This case reports a 25‐year‐old allo‐HCT recipient with severe HCoV‐OC43 pneumonia who responded well to off‐label nirmatrelvir/ritonavir. It is the first such report that show the drug may benefit immunocompromised patients with this infection, though further studies are needed to confirm efficacy.
Mingzhou Zhang, Ting Tang, Mingxia Zheng, Menglin Luo, Zhi Xu, Guansong Wang   +5 more
wiley   +1 more source

Aerosolised pentamidine for Pneumocystis carinii pneumonia in patients with acquired immunodeficiency syndrome Aerosol de pentamidina no tratamento da pneumonia por Pneumocystis carinii em pacientes com a síndrome da imunodeficiência adquirida

Revista do Instituto de Medicina Tropical de São Paulo, 1990
The goal of this study was to evaluate inhaled pentamidine for the treatment of patients with mild and moderate Pneumocystis carinii pneumonitis. Eight adults with AIDS and pneumocystis pneumonia (4 with a first episode and 4 with a repeat pneumocystosis)
Adriana Weinberg, Sebastião A. Dantonio, Maria Irma S. Duarte, Wilson L. Pedreira Jr., Antonio A. Barone, Shinishi Ishioka   +5 more
doaj   +1 more source

Infection Complications in Pediatric Patients With Inborn Errors of Immunity After Umbilical Cord Blood Transplantation: A Chinese Single‐Center Study

Transplant Infectious Disease, Volume 28, Issue 3, May/June 2026.
This study reveals that infections are highly prevalent in pediatric IEI patients after umbilical cord blood transplantation, with early‐stage infections and bloodstream infections strongly associated with poorer survival. These findings advocate for risk‐stratified surveillance and preemptive strategies in high‐risk subgroups.
Zhongling Wei, Ping Wang, Wenjin Jiang, Jie Man, Ying Huang, Xiaochuan Wang, Hongsheng Wang, Xiaowen Qian, Xiaowen Zhai   +8 more
wiley   +1 more source

Ploidy of cell-sorted trophic and cystic forms of Pneumocystis carinii.

PLoS ONE, 2011
Once regarded as an AIDS-defining illness, Pneumocystis pneumonia (PcP) is nowadays prevailing in immunocompromised HIV-negative individuals such as patients receiving immunosuppressive therapies or affected by primary immunodeficiency.
Anna Martinez, El Moukhtar Aliouat, El Moukhtar Aliouat, Annie Standaert-Vitse, Elisabeth Werkmeister, Muriel Pottier, Claire Pinçon, Eduardo Dei-Cas, Cécile-Marie Aliouat-Denis   +8 more
doaj   +1 more source

Enfortumab vedotin plus pembrolizumab in treatment‐naïve metastatic urothelial carcinoma patients: An Austrian real‐world analysis

International Journal of Cancer, Volume 158, Issue 6, Page 1654-1665, 15 March 2026.
What's new? New antibody‐drug conjugates (ADCs) and immunotherapies have helped expand treatment options for urothelial carcinoma (UC). Clinical trials suggest that the ADC enfortumab vedotin (EV) and the immunotherapeutic agent pembrolizumab, when used in combination, are especially effective against UC.
Dora Niedersuess‐Beke, Karl Mayrhofer, Johanna Krauter, Johannes Franke, Dominic Vais, Maximillian Pallauf, David Kiesl, Ferdinand Luger, Jacob Pfuner, Angelika Terbuch, Thomas Bauernhofer, Jasmin Spielgelberg, Andreas Banner, Stefan Aufderklamm, Clemens Wiesinger, Susanne Schnabel, Simon Peter Gampenrieder, Josef Mühlmann, Sonia Vallet, Sabine Weibrecht, Franz Stoiber, Haleh Andalibi, Harun Fajkovic, Hossein Taghizadeh, Jan Miechowiecki, Roman Taedcke, Daniel Heintel, Shahrokh F. Shariat, Martin Pichler, Wolfgang Hilbe, Renate Pichler   +30 more
wiley   +1 more source

SYTO-13, a Viability Marker as a New Tool to Monitor In Vitro Pharmacodynamic Parameters of Anti-Pneumocystis Drugs.

PLoS ONE, 2015
While Pneumocystis pneumonia (PcP) still impacts the AIDS patients, it has a growing importance in immunosuppressed HIV-negative patients. To determine the anti-Pneumocystis therapeutic efficacy of new compounds, animal and in vitro models have been ...
Annie Standaert-Vitse, Cécile-Marie Aliouat-Denis, Anna Martinez, Sara Khalife, Muriel Pottier, Nausicaa Gantois, Eduardo Dei-Cas, El Moukhtar Aliouat, El Moukhtar Aliouat   +8 more
doaj   +1 more source