Comparative genomics suggests that the human pathogenic fungus Pneumocystis jirovecii acquired obligate biotrophy through gene loss. [PDF]
, 2014 Pneumocystis jirovecii is a fungal parasite that colonizes specifically humans and turns into an opportunistic pathogen in immunodeficient individuals. The fungus is able to reproduce extracellularly in host lungs without eliciting massive cellular death.
Cissé, O.H., Hauser, P.M., Pagni, M.
core +1 more source
BMC Infectious Diseases, 2019 Background Pneumocystis jirovecii pneumonia (PCP) is one of the most common HIV-related opportunistic infections. The diagnosis of PCP is based on analyses from respiratory tract specimens which may require the invasive procedure of a diagnostic ...
Helena Hammarström +6 more
doaj +1 more source
Management of Pneumocystis Jirovecii pneumonia in HIV infected patients: current options, challenges and future directions [PDF]
, 2010 Jose G Castro1, Maya Morrison-Bryant21Division of Infectious Diseases, University of Miami Miller School of Medicine, Miami, Florida, USA; 2Jackson Memorial Hospital/University of Miami Infectious Diseases Fellowship Program, Miami, Florida, USAAbstract:
Jose G Castro, Maya Morrison-Bryant
core +2 more sources
Mechanisms of Surface Antigenic Variation in the Human Pathogenic Fungus Pneumocystis jirovecii. [PDF]
, 2017 Microbial pathogens commonly escape the human immune system by varying surface proteins. We investigated the mechanisms used for that purpose by <i>Pneumocystis jirovecii</i> This uncultivable fungus is an obligate pulmonary pathogen that ...
Amanda Luraschi +6 more
core +3 more sources
Acta Médica Portuguesa, 2016 Introdução: A pneumonia por Pneumocystis jirovecii é das doenças infecciosas oportunistas mais comuns em infectados por vírus da imunodeficiência humana, sendo, actualmente, em Portugal a infecção definidora de sida mais reportada.
Vilma Grilo, Aida Pereira
doaj +1 more source
Clinical characteristics of pneumonia in non-HIV patients and prognostic factors including microbiological genotypes [PDF]
, 2011 Background The number of patients with non-HIV Pneumocystis pneumonia (PCP) is increasing with widespread immunosuppressive treatment. We investigated the clinical characteristics of non-HIV PCP and its association with microbiological ...
Yasufumi Matsumura +10 more
core +1 more source
Unusual Radiographic Presentation of Pneumocystis Pneumonia in a Patient with AIDS. [PDF]
, 2017 Pneumocystis jirovecii pneumonia (PCP) typically presents as an interstitial and alveolar process with ground glass opacities on chest computed tomography (CT).
Block, Brian L +6 more
core +3 more sources
Improved detection of Pneumocystis jirovecii in upper and lower respiratory tract specimens from children with suspected pneumocystis pneumonia using real-time PCR: a prospective study [PDF]
, 2011 BACKGROUND: Pneumocystis pneumonia (PCP) is a major cause of hospitalization and mortality in HIV-infected African children. Microbiologic diagnosis relies predominantly on silver or immunofluorescent staining of a lower respiratory tract (LRT) specimens
Andrew Whitelaw +7 more
core +3 more sources
Molecular Detection of Pneumocystis jirovecii in the Bronchoalveolar Lavage Samples in Patients with Various Pulmonary Disorders(Original Article) [PDF]
Journal of Ardabil University of Medical Sciences, 2023 Background: Pneumocystis jirovecii (P. jirovecii) causes Pneumocystis pneumonia (PCP) in people, especially the immunocompromised ones. It is also one of the serious causes of numerous lung problems in affected patients.
Narges Chitsaz +9 more
doaj
Journal of Infection in Developing Countries, 2010 Introduction: Pneumocystis jirovecii dihydropteroate synthase (DHPS) gene mutations' (55th and 57th codon) association with prior sulfa prophylaxis failure has been reported from both developed and developing countries.
Anuj Kumar Tyagi +9 more
doaj +1 more source