Results 41 to 50 of about 1,205,800 (294)

C-reactive Protein Versus Neutrophil/lymphocyte Ratio in Differentiating Bacterial and Non-bacterial Pneumonia in Children

Journal of Nepal Health Research Council, 2017
Background: Pneumonia is a leading cause of childhood mortality in a low resource country. Simple laboratory markers can help differentiate between bacterial and non-bacterial pneumonias for appropriate management.
Eva Gauchan, Sudhir Adhikari
doaj   +1 more source

Comparison of Short- versus Long-Course Antimicrobial Therapy of Uncomplicated Bacterial Pneumonia in Dogs: A Double-Blinded, Placebo-Controlled Pilot Study

Animals, 2021
Current treatment for canine bacterial pneumonia relies on protracted courses of antimicrobials (3–6 weeks or more) with recommendations to continue for 1–2 weeks past resolution of all clinical and thoracic radiographic abnormalities. However, in humans,
Aida I. Vientós-Plotts, Isabelle Masseau, Carol R. Reinero   +2 more
doaj   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

ANTIBIOTIC STEWARDSHIP STRATEGIES TO LIMIT INAPPROPRIATE ANTIBIOTIC USE AND REDUCE MULTI-DRUG RESISTANT PATHOGENS DURING COVID-19 PANDEMIC

International Journal of Infectious Diseases, 2023
Antibiotics have been extensively used in COVID-19 patients without a clear indication. COVID-19 pneumonia is associated with a mortality up to 20% varying by country with the number of global deaths over 5 million. Antibiotics have been extensively used
Anucha Apisarnthanarak
doaj   +1 more source

Decreasing incidence and determinants of Bacterial Pneumonia in people with HIV: The Swiss HIV Cohort Study [PDF]

, 2022
BACKGROUND Bacterial pneumonia is one of the leading reasons for hospitalization among people with HIV (PWH), yet there is limited evidence regarding its drivers in the era of potent antiretroviral therapy.
Battegay, Manuel, Calmy, A., Hauser, C., Günthard, Huldrych F, Roth, J.A., Cavassini, M., Battegay, M., Balakrishna, S., Calmy, Alexandra, Bernasconi, Enos, Balakrishna, Suraj, Kachalov, Viacheslav, Swiss HIV Cohort Study, Schmid, Patrick, Kouyos, Roger D, Furrer, Hansjakob, Wolfensberger, Aline, Kusejko, K., Schmid, P., Furrer, H., Kouyos, R.D., Kachalov, V., Scherrer, A.U., Günthard, H.F., Roth, Jan A, Cavassini, Matthias; https://orcid.org/, Kusejko, Katharina, Scherrer, Alexandra U, Hauser, Christoph, Wolfensberger, A., Cavassini, Matthias, Bernasconi, E.   +31 more
core   +2 more sources

Extending Service Beyond Active Duty: Generalizability of Rheumatoid Arthritis Research Conducted Among U.S. Veterans

Arthritis Care &Research, Accepted Article.
Biomedical research involving United States Veterans continues to advance healthcare beyond the Veterans Health Administration. This is particularly true in rheumatoid arthritis (RA), where Veteran‐centric research has uncovered novel insights into pathogenesis, risk factors, and disease manifestations, informing clinical care and research across both ...
Austin M. Wheeler, Joshua F. Baker, Jennifer L. Barton, Maria I. Danila, Tate M. Johnson, Kamini Kuchinad, Kaleb Michaud, Amir A. Razmjou, J. Steuart Richards, Namrata Singh, Isaac D. Smith, Katherine D. Wysham, Grant W. Cannon, Bryant R. England, Amy Joseph, Deana Lazaro, Katherine P. Liao, Courtney Loecker, Andreas Reimold, Beth I. Wallace, Ted R. Mikuls   +20 more
wiley   +1 more source

Recombinant plants provide a new approach to the production of bacterial polysaccharide for vaccines. [PDF]

, 2014
Bacterial polysaccharides have numerous clinical or industrial uses. Recombinant plants could offer the possibility of producing bacterial polysaccharides on a large scale and free of contaminating bacterial toxins and antigens.
G. C. Whitelam (7665758), Marie Goldrick (324989), Roberts Ian S., Garry C. Whitelam (519301), Andrew, PW, Patel, Alexandra J.F., Whitelam, Garry C, Claire M. Smith (7665743), Peter W. Andrew (153608), Roberts, Ian S, Whitelam, Garry C., Patel Alexandra J. F., Roberts, IS, K. C. Gough (7665749), Glenn, S, Gough Kevin C., Andrew, Peter W, S. C. Fry (7665746), Alexandra J F Patel, Stephen C Fry, Garry C Whitelam, Kevin C Gough, Gough, KC, Sarah Glenn (519300), Fry Stephen C., Andrew Peter W., Gough, Kevin C, Whitelam, GC, Sarah Glenn, Fry, Stephen C., Claire M. Smith (519296), Roberts, Ian S., Ian S. Roberts (159693), Whitelam Garry C., Peter W Andrew, Smith, Claire M, Patel, Alexandra J F, Patel, AJ, Fry, Stephen C, Stephen C. Fry (519297), Andrew, Peter W., Kevin C. Gough (519298), Ian S Roberts, Fry, SC, Goldrick, M, Smith Claire M., Alexandra J. F. Patel (519299), Goldrick Marie, Marie Goldrick, M. Goldrick (7665755), Goldrick, Marie, Alexandra J. F. Patel (7665752), Gough, Kevin C., Glenn, Sarah, Glenn Sarah, Smith, Claire M., Claire M Smith, Smith, CM, I. S. Roberts (6341096)   +58 more
core   +1 more source

Incidence, Risk Factors and Management of Adverse Events in Contemporary Real‐World Care of Children with Juvenile Idiopathic Arthritis

Arthritis Care &Research, Accepted Article.
Objective We describe the frequency, risk factors, severity, and management of actionable and serious adverse events (AAE and SAE) in children with newly diagnosed Juvenile Idiopathic Arthritis (JIA) in Canada. Methods We enrolled patients within 3 months of JIA diagnosis in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry,
Bashayer Alnuaimi, Roberta A. Berard, Jean‐Philippe Proulx‐Gauthier, Heinrike Schmeling, Michelle Batthish, Gilles Boire, Adam M. Huber, Dax G. Rumsey, Jaime Guzman, Gaëlle Chédeville, The CAPRI registry Investigators   +10 more
wiley   +1 more source

Real‐world effectiveness and safety of secukinumab in giant cell arteritis: an Italian multicentre cohort study

Arthritis Care &Research, Accepted Article.
Objective The objective of this study was to evaluate the real‐world effectiveness and safety of secukinumab in giant cell arteritis (GCA) patients. Methods This multicentre retrospective study included patients with GCA who received secukinumab at 14 Italian centres with at least 6 months of follow‐up.
Luca Iorio, Federica Davanzo, Caterina Ricordi, Milena Bond, Ruggiero Mascolo, Jacopo Mora, Alessandro Tomelleri, Angelo Fassio, Francesca Cuzzocrea, Sara Monti, Edoardo Conticini, Fabiola Atzeni, Paolo Delvino, Carlotta Nannini, Augusta Ortolan, Francesco Pollastri, Ester Vivaldelli, Chiara Marvisi, Paola Toniati, Antonio Brucato, Alessandra Milanesi, Francesca Regola, Enrico Tombetti, Lorenzo Dagna, Roberta Ramonda, Christian Dejaco, Luca Quartuccio, Carlo Salvarani, Roberto Padoan, The Italian Society of Rheumatology Vasculitis Study Group   +29 more
wiley   +1 more source

Target product profile for a diagnostic assay to differentiate between bacterial and non-bacterial infections and reduce antimicrobial overuse in resource-limited settings: an expert consensus [PDF]

, 2016
Acute fever is one of the most common presenting symptoms globally. In order to reduce the empiric use of antimicrobial drugs and improve outcomes, it is essential to improve diagnostic capabilities.
Zorzet, A., Tadesse, BT, Paul N Newton, Newton, P.N., Quique Bassat (89288), Lubell, Yoel,, Zorzet, Anna, D'Acremont, Valerie,, Bassat, Quique,, Norbert Heinrich, Crump, John A.,, Paul N. Newton (132889), Yoel Lubell, Zorzet, A, Valerie D’Acremont (3079494), Dolinger, D.L., Anna Zorzet, Anna Zorzet (3079506), Newton, PN, Iveth J. González (137011), Chua, Arlene,, Rodwell, T.J., D'Acremont, V., González, Iveth J, David L Dolinger, Heinrich, Norbert,, Dittrich, Sabine, Dittrich, S, Gonzalez, Iveth J.,, Rodwell, Timothy J.,, González, I.J., Norbert Heinrich (175590), Tängdén, Thomas,, Page, A.L., Chua, A., Dolinger, David L., Dolinger, David L, John A. Crump (231237), Tilahun, Birkneh Tilahun, Thomas Tängdén, Newton, Paul, Birkneh Tilahun Tadesse, Lubell, Y, Francis Moussy, Timothy J Rodwell, Bassat, Quique, Newton, Paul N.,, Tängdén, T., Tadesse, Birkneh Tilahun,, Thomas Tängdén (3079503), Arlene Chua, Moussy, F, Moussy, F., Rodwell, Timothy J., Page, Anne-Laure, Lubell, Yoel, Tadesse, B.T., Bassat Orellana, Quique, Valerie D'Acremont, Birkneh Tilahun Tadesse (769116), Crump, John A., Bassat, Q, John A Crump, Chua, A, Newton, Paul N., Bassat, Q., Acremont, Valerie D’, González, Iveth J., Sabine Dittrich (85996), Tängdén, Thomas, Newton, Paul N, David L. Dolinger (3079500), Page, Anne-Laure, Moussy, Francis, Anne-Laure Page, Crump, J.A., Rodwell, Timothy J, Crump, JA, Tadesse, Birkneh Tilahun, Timothy J. Rodwell (3079497), Iveth J González, González, IJ, Chua, Arlene, Zorzet, Anna,, Heinrich, N, Dittrich, S., Yoel Lubell (88683), Page, Anne-Laure,, Page, AL, D'Acremont, Valerie, Dolinger, David L.,, Heinrich, N., Tängdén, T, Crump, John A, Heinrich, Norbert, Dittrich, Sabine,, Arlene Chua (134856), Sabine Dittrich, Dolinger, DL, Anne-Laure Page (247439), D'Acremont, V, Rodwell, TJ, Moussy, Francis,, Quique Bassat, Lubell, Y., Francis Moussy (127840)   +105 more
core   +1 more source