Results 41 to 50 of about 21,263 (258)

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Comparison of Short- versus Long-Course Antimicrobial Therapy of Uncomplicated Bacterial Pneumonia in Dogs: A Double-Blinded, Placebo-Controlled Pilot Study

Animals, 2021
Current treatment for canine bacterial pneumonia relies on protracted courses of antimicrobials (3–6 weeks or more) with recommendations to continue for 1–2 weeks past resolution of all clinical and thoracic radiographic abnormalities. However, in humans,
Aida I. Vientós-Plotts, Isabelle Masseau, Carol R. Reinero   +2 more
doaj   +1 more source

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source

Fungal pneumonia concealing bacterial pneumonia: a diagnostic dilemma

Monaldi Archives for Chest Disease, 2023
We describe the case of a 61-year-old diabetic man affected by Achromobacter denitrificans. He was immunocompetent and did not have any past history of chronic lung disease.
Christie George Joseph, Madhusmita Mohanty Mohapatra, Manju Rajaram, Jayabharathi Palanivel, Balasubramanian Velappan   +4 more
doaj   +1 more source

Enzymatic DNA Reaction Networks for Orchestrating Stimuli‐Dependent Temporal Molecular Pulse

Advanced Science, EarlyView.
We present an enzymatic DNA reaction network (EDRN) that encodes nucleic‐acid targets in time, converting inputs into a universal strand and then into programmable transient fluorescence pulses. With time‐color multiplexing, EDRN enables single‐tube high‐plex nucleic acid detection and shows strong agreement with clinical sequencing across 32 specimens.
Jiayu Yang, Yali Chang, Zibin Chu, Linghao Zhang, Tengfang Zhang, Dai Erhei, Xin Su, Zhe Yin   +7 more
wiley   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Accuracy of the diagnosis of pneumonia in Canadian pediatric emergency departments: A prospective cohort study.

PLoS ONE
BackgroundThe diagnosis of pediatric pneumonia and determination of the likely pathogen are complicated as the clinical picture overlaps with other respiratory illnesses, interpretation of radiographs is subjective, and laboratory results are rarely ...
Joan L Robinson, James D Kellner, Jennifer Crotts, Gabino Travassos, Guanmin Chen, Valerie G Kirk, Martin Pusic, Martin Reed, Sarah Reid, Michael Weinstein, Ravi Bhargava, Maala Bhatt, Kathy Boutis, Sarah Curtis, Serge Gouin, Tim Lynch, Richard van Wylick, David W Johnson   +17 more
doaj   +1 more source

The role of indoor air pollution and other factors in the incidence of pneumonia in under-five children [PDF]

, 2004
Background The World Health Organization has asked for a special attention to the relation between pneumonia and indoor air pollution, i.e., household biomass fuel smoke, cigarette smoke, and mosquito coil smoke, especially in developing countries ...
Iskandar, Iskandar, Surjono, Ahmad, Wastoro, Dwi, Sunyataningkamto, Sunyataningkamto, Budiman, Budiman, Lestari, Endang Dewi, Wibowo, Tunjung, Alan , Alan   +7 more
core  

Potential use of serum based quantitative real-time PCR for the detection of pneumonia pathogens in a densely colonised population [PDF]

, 2012
Molecular methods offer improvement in the detection of causative pneumonia pathogens, but there are concerns of false positive results. Here we validate quantitative real-time PCR (qPCR) assays for the detection of Streptococcus pneumoniae and ...
Binks, Michael J, Smith-Vaughan, Heidi C, Leach, Amanda J, Kaestli, Mirjam, Lai, Jana YR   +4 more
core   +1 more source

Advanced Dental Composite Technology via Bisilanized Dual‐Action Nanofillers for Biofilm Control

Advanced Science, EarlyView.
A multimodal research strategy has led to the development of an innovative resin‐based composite (RBC) with dual antibacterial action. The S_CM‐RBC formula showed strong antibiofilm activity, excellent mechanical strength, and biosafety. It effectively controlled oral bacteria in prevention of caries recurrence, and maintained pulp health in a rat ...
Chenmin Yao, Line Etiennot, Naiera Zayed, Shengjie Liang, Mehraveh Saghi, Jelle Verdonck, Lingyue Liu, Fei Zhang, Wim Teughels, Cui Huang, Kirsten Van Landuyt, Bart Van Meerbeek   +11 more
wiley   +1 more source