Results 111 to 120 of about 374,956 (253)

Janus kinase and calcineurin‐inhibitor combination in anti‐MDA5 dermatomyositis: No significant survival benefit but reassuring safety profile

Journal of Internal Medicine, Volume 299, Issue 2, Page 228-240, February 2026.
Abstract Objectives Anti‐MDA5 dermatomyositis (anti‐MDA5 DM) is the most severe subtype of dermatomyositis, due to its pulmonary involvement. Current treatment involves corticosteroids and immunosuppressants, but variability in responses exists. This study aims to evaluate the efficacy and safety of Janus kinase (JAK)– and calcineurin–inhibitor ...
Valentine Pagis, Quentin Astouati, Lucas Pacoureau, Yann Nguyen, Pierre Bay, Antoine Roux, Laure Gallay, Vincent Cottin, Benjamin Terrier, Alain Meyer, Charles Cerf, Mathilde Neuville, Baptiste Hervier, Arthur Renaud, Benoit Suzon, Nicolas Schleinitz, Thomas Papo, Pascaline Priou, Arsène Mekinian, Audrey Ullmer, Erwan Oehler, Noémie Gensous, Alice Berezne, Luc De Saint Martin, Thierry Marhadour, Mickaël Martin, Amélie Servettaz, Maxime Samson, Laurent Gilardin, Pierre Charles, Juliette Woessner, Thierry Carmoi, Baptiste Dilly, Wladimir Mauhin, Nicolas Baillet, Sébastien Humbert, Benjamin Thoreau, Marine Lemaitre, Claire Le Pendu, Pierre Loiseau, Thomas Quemeneur, Elodie Blanchard, Nicol Voermans, David Launay, Hilario Nunes, Olivier Benveniste, Yurdagul Uzunhan, Yves Allenbach   +47 more
wiley   +1 more source

Clinical and translational research in Pneumocystis and Pneumocystis pneumonia*

Parasite, 2011
Pneumocystis pneumonia (PcP) remains a significant cause of morbidity and mortality in immunocompromised persons, especially those with human immunodeficiency virus (HIV) infection.
Huang L.
doaj   +1 more source

Rationale for Prolonged Glucocorticoid Use in Pediatric ARDS: What the Adults Can Teach Us. [PDF]

, 2016
Based on molecular mechanisms and physiologic data, a strong association has been established between dysregulated systemic inflammation and progression of acute respiratory distress syndrome (ARDS).
Meduri, Gianfranco Umberto, Schwingshackl, Andreas   +1 more
core   +1 more source

Microarray studies on effects of Pneumocystis carinii infection on global gene expression in alveolar macrophages

BMC Microbiology, 2010
Background Pneumocystis pneumonia is a common opportunistic disease in AIDS patients. The alveolar macrophage is an important effector cell in the clearance of Pneumocystis organisms by phagocytosis.
Liao Chung-Ping, Xuei Xiaoling, Liu Yunlong, Cheng Bi-Hua, Lu Debao, Lasbury Mark E, Durant Pamela J, Lee Chao-Hung   +7 more
doaj   +1 more source

Integrating tuberculosis and HIV services in low- and middle-income countries: a systematic review.

, 2012
OBJECTIVES: Given the imperative to scale up integrated tuberculosis (TB) and HIV services in settings where both are of major public health importance, we aimed to synthesise knowledge concerning implementation of TB/HIV service integration.
Atun, Briggs, Dixon-Woods, Dong, Gandhi, Gunneberg, Harris, Hausler, Laserson, Levin, Maher, Martinot, Micek, Miti, Moher, Ramachandran, Shakarishvilli, Shetty, Shrestha, Ssemafumu, Sutton, Terris-Prestholt, The World Bank Group, Thomas, USAID, Uyei, Van Rie, Vassall, Vijay, Wandwalo, WHO, WHO, WHO, WHO, WHO, WHO, Zachariah   +36 more
core   +1 more source

Development and Validation of a Pneumocystis jirovecii Real-time Polymerase Chain Reaction Assay for Diagnosis of Pneumocystis Pneumonia

Canadian Journal of Infectious Diseases and Medical Microbiology, 2015
BACKGROUND: Pneumocystis jirovecii (PJ), a pathogenic fungus, causes severe interstitial Pneumocystis pneumonia (PCP) among immunocompromised patients. A laboratory-developed real-time polyermase chain reaction (PCR) assay was validated for PJ detection ...
Deirdre L Church, Anshula Ambasta, Amanda Wilmer, Holly Williscroft, Gordon Ritchie, Dylan R Pillai, Sylvie Champagne, Daniel G Gregson   +7 more
doaj   +1 more source

Transcriptomic and Proteomic Approaches to Finding Novel Diagnostic and Immunogenic Candidates in Pneumocystis

mSphere, 2019
Pneumocystis pneumonia is the most common serious opportunistic infection in patients with HIV/AIDS. Furthermore, Pneumocystis pneumonia is a feared complication of the immunosuppressive drug regimens used to treat autoimmunity, malignancy, and ...
Taylor Eddens, Waleed Elsegeiny, David Ricks, Meagan Goodwin, William T. Horne, Mingquan Zheng, Jay K. Kolls   +6 more
doaj   +1 more source

Pneumocystis jirovecii colonization in chronic pulmonary disease

Parasite, 2011
Pneumocystis jirovecii causes pneumonia in immunosuppressed individuals. However, it has been reported the detection of low levels of Pneumocystis DNA in patients without signs and symptoms of pneumonia, which likely represents colonization.
Gutiérrez S., Respaldiza N., Campano E., Martínez-Risquez M.T., Calderón E.J., De La Horra C.   +5 more
doaj   +1 more source

Pneumocystis carinii pneumonia in renal transplant recipients treated with cyclosporin [PDF]

, 1989
Four cases of pneumocystis carinii pneumonia occurred among 38 renal transplant recipients. Diagnosis was confirmed by cyst concentration technique in 2 cases.
中根, 佳宏, 友吉, 唯夫, 小玉, 正智, 小西, 平, 新井, 豊, 朴, 勺, 沖野, 功次, 石田, 章, 神波, 照夫, 若林, 賢彦, 迫, 裕孝, 金, 哲將   +11 more
core  

A case of pneumocystis carinii pneumonia after chemotherapy of bladder tumor [PDF]

, 1985
This is a case report on a 70-year-old male patient. During chemotherapy treatment after a bladder tumor operation, the patient had a complication of pneumonia which did not respond to various antibiotics.
佐々木, 進, 大島, 升, 小笹, 喜丘, 池内, 博和   +3 more
core