Results 91 to 100 of about 402,090 (258)

A novel case of autosomal recessive CARD11 loss‐of‐function underlying impaired antiviral immunity and a review of literature

Clinical &Translational Immunology, Volume 15, Issue 5, 2026.
We report on a patient homozygous for a novel autosomal recessive loss‐of‐function CARD11 variant, with susceptibility to live attenuated virus (LAV) vaccines and impaired clearance of multiple naturally acquired respiratory viral infections. Inborn errors of immunity affecting the CARD11‐BCL10‐MALT1 (CBM) complex should be considered in individuals ...
Hamish Anderson, Cecilia Verryt, Paula Keating, Thomas Saunders, Samuel Dalton, Barry D Hock, Liping Goddard, Kylie Drake, Anja Werno, John O'Donnell, Jeffrey R Stinson, Andrew L Snow, Kuang‐Chih Hsiao   +12 more
wiley   +1 more source

Torque Teno Virus in Bronchoalveolar Lavage Fluid of Hematological Patients and Association With Pathogens

Journal of Medical Virology, Volume 98, Issue 5, May 2026.
ABSTRACT Torque teno virus (TTV) replication is tightly modulated by the host immune response. As such, TTV viremia has been investigated as a biomarker of immune competence for monitoring the risks of allograft rejection and opportunistic infections in solid organ transplant recipients.
Mahdi Ouafi, Camille Cordier, David Beauvais, Serge Alfandari, Marie Titécat, Romain Dubois, Frédéric Wallyn, Séverine Loridant, Fanny Vuotto, Micha Srour, Céline Berton, Valérie Coiteux, Ibrahim Yakoub‐Agha, Boualem Sendid, Didier Hober, Enagnon Kazali Alidjinou   +15 more
wiley   +1 more source

Does quality of care differ when HIV patients are treated by non-specialist and specialist HIV healthcare providers in developed countries? A Systematic narrative review [PDF]

, 2015
Copyright © 2015 by authors and Scientific Research Publishing Inc.Peer reviewedPublisher ...
Okpo, Emmanuel, Poobalan, Amudha, Sokhom, Bossakara, Tonna, Ivan   +3 more
core   +1 more source

Efficacy of upadacitinib induction for pediatric inflammatory bowel disease

JPGN Reports, Volume 7, Issue 2, Page 296-300, May 2026.
Abstract Objectives Upadacitinib, a second‐generation Janus kinase (JAK) inhibitor, is approved for moderate to severe Crohn's disease (CD) and ulcerative colitis (UC) in adults. Its efficacy in pediatric patients remains unclear, though early reports suggest benefits in refractory inflammatory bowel disease (IBD).
Evan Greenhall, Nina Gautam, Paula Prieto‐Jimenez, Elizabeth Hilow, Ashish Patel, Brad Pasternak   +5 more
wiley   +1 more source

Common invasive fungal diseases: an overview of invasive candidiasis, aspergillosis, cryptococcosis, and Pneumocystis pneumonia.

Swiss medical weekly, 2016
Every year, Candida, Aspergillus, Cryptococcus and Pneumocystis infect an estimated two million individuals worldwide. Most are immunocompromised or critically ill.
Yvonne Schmiedel, S. Zimmerli
semanticscholar   +1 more source

Immune responses of different hosts to Pneumocystis infection

European Respiratory Review
Pneumocystis pneumonia constitutes a critical life-threatening opportunistic infection, where the host's immune response plays a central role in its pathogenesis.
Jun Li, Xiangdong Mu, Haichao Li, Xinmin Liu   +3 more
doaj   +1 more source

Diagnosis and management of pneumonia in the emergency department. [PDF]

, 2008
Pneumonia is a condition that is often treated by emergency physicians. This article reviews the diagnosis and management of pneumonia in the emergency department and highlights dilemmas in diagnostic testing, use of blood and sputum cultures, hospital ...
Abrahamian, Fredrick M, Moran, Gregory J, Talan, David A   +2 more
core  

Laryngeal Transplantation in Cancer Patients: Evaluation of Surgical Outcomes and Functional Recovery

MedComm, Volume 7, Issue 5, May 2026.
Our pilot clinical study in laryngeal transplantation achieved divergent outcomes: two cases maintained functional speech/swallowing with around 2 year graft survival and have been ongoing, while two succumbed to sepsis (10mo) and hemorrhagic recurrence (11mo).
Zheng Jiang, Mailudan Ainiwaer, Pengwei Zhao, Yansheng Hu, Xin Yang, Yu Xiong, Bin Zeng, Longhao Wang, Jun Liu, Fei Chen   +9 more
wiley   +1 more source

Treosulfan–fludarabine conditioning in infants with severe combined immunodeficiencies: Extended study of the UK paediatric treosulfan study

British Journal of Haematology, Volume 208, Issue 5, Page 1713-1723, May 2026.
Summary Allogeneic haematopoietic stem cell transplantation (HSCT) is a curative therapy for severe combined immunodeficiency (SCID). Conditioning improves donor engraftment and freedom from immunoglobulin replacement (IgR) but increases the risks of acute and late toxicity. Treosulfan, a reduced toxicity alkylating agent, has emerged as an alternative
Su Han Lum, Sinéad Greener, Irum Latif Memon, Persis Amrolia, Zohreh Nademi, Robert Chiesa, Juliana Silva, Helen Young, Stephen Owens, Eleri Williams, Khuen Foong Ng, Terry Flood, Andrew R Gennery, Sophie Hambleton, Kanchan Rao, Mary Slatter   +15 more
wiley   +1 more source

Update on the diagnosis and treatment of pneumonia

Therapeutic Advances in Respiratory Disease, 2011
Pneumocystis is an opportunistic fungal pathogen that causes an often-lethal pneumonia in immunocompromised hosts. Although the organism was discovered in the early 1900s, the first cases of Pneumocystis pneumonia in humans were initially recognized in ...
Eva M. Carmona, Andrew H. Limper
doaj   +1 more source