Results 41 to 50 of about 1,206 (76)

The role of blinatumomab in adult acute B lymphoblastic leukaemia

British Journal of Haematology, EarlyView.
Blinatumomab, a CD19‐directed bispecific T‐cell engager, has become a crucial part of BCP‐ALL therapy in r/r disease, MRD‐positive disease and has recently been implemented into first‐line therapy of BCP‐ALL. This review discusses important clinical trials with a focus on blinatumomab in first‐line therapy of adult BCP‐ALL.
Anne C. Wilke, Nicola Gökbuget
wiley   +1 more source

Efficacy and Safety of Bendamustine‐Rituximab for Nodular Lymphocyte Predominant Hodgkin Lymphoma

European Journal of Haematology, EarlyView.
ABSTRACT Introduction Bendamustine‐rituximab (BR) has demonstrated efficacy and tolerability in the treatment of various indolent B‐cell lymphomas, but there is limited data regarding its outcomes in nodular lymphocyte predominant B‐cell (Hodgkin) lymphoma (NLPBL).
Alexander Robin, Carolyn Owen, Sarah Perry, Lesley Street, Neil Chua, Douglas Stewart, Robert Puckrin   +6 more
wiley   +1 more source

Pneumocystis pneumonia in a treatment-naive rheumatoid arthritis patient

IDCases, 2019
A HIV-negative, newly diagnosed patient with rheumatoid arthritis (RA) was found to have pneumocystis jiroveci pneumonia. The infection was treated with three weeks of atovaquone and corticosteroids.
Anuoluwapo Shobayo, Chiemeziem Nwanyanwu, Edward Chapnick   +2 more
doaj  

Update on the diagnosis and treatment of pneumonia

Therapeutic Advances in Respiratory Disease, 2011
Pneumocystis is an opportunistic fungal pathogen that causes an often-lethal pneumonia in immunocompromised hosts. Although the organism was discovered in the early 1900s, the first cases of Pneumocystis pneumonia in humans were initially recognized in ...
Eva M. Carmona, Andrew H. Limper
doaj   +1 more source

The UK Infected Blood Inquiry: A Personal Reflection

Haemophilia, EarlyView.
ABSTRACT The UK Infected Blood Inquiry (IBI) considered the transfusion transmitted infections hepatitis B and C, HIV, and vCJD. The inquiry lasted 6 years during 2018 to 2024 and reported to the UK parliament on 20 May, 2024. It concluded that at least 3000 people died because of the recklessness and obstinacy of officialdom and it has been reported ...
Christine A. Lee
wiley   +1 more source

Aspergillus After Lung Transplantation: Prophylaxis, Risk Factors, and the Impact on Chronic Lung Allograft Dysfunction

Transplant Infectious Disease, EarlyView.
Out of 274 lung transplant (LTx) patients, 89 (32%) developed invasive aspergillosis IA. Factors associated with IA were mycophenolate mofetil use, airway stenosis, Aspergillus cultured pre‐LTx, chronic lung allograft dysfunction (CLAD), and acute rejection. The role of nebulized amphotericin B and statins for prevention of IA remains unclear. ABSTRACT
Johanna P. van Gemert, Ger Jan Fleurke, Onno W. Akkerman, C. Tji. Gan, Willie N. Steenhuis, Huib A. M. Kerstjens, Erik A. M. Verschuuren, Douwe F. Postma   +7 more
wiley   +1 more source

Risk Factors for Breakthrough Pneumocystis carinii Pneumonia on Aerosol Pentamidine Prophylaxis

Canadian Respiratory Journal, 1995
OBJECTIVE: To identify baseline characteristics of human immunodeficiency virus (HIV)-infected individuals on aerosol pentamidine for Pneumocystis carinii prophylaxis that are predictive of subsequent breakthrough Pneumocystis carinii pneumonia (PCP).
RA McIvor, AR Rachlis, P Berger, LR Lee Pack, Charles K Chan   +4 more
doaj   +1 more source

A protracted course of Pneumocystis pneumonia in the setting of an immunosuppressed child with GMS-negative bronchoalveolar lavage

Medical Mycology Case Reports, 2016
We report a case of Pneumocystis pneumonia in a 5-year-old male with Trisomy 21 and acute lymphoblastic leukemia. The lack of response to trimethoprim-sulfamethoxazole raised concerns for antimicrobial resistance.
Taylor Eddens, Eunkyung Song, Monica I. Ardura, Jay K. Kolls   +3 more
doaj   +1 more source

Bacteremia in Pediatric Solid Organ Transplant Recipients within 1 Year of Transplant

Transplant Infectious Disease, EarlyView.
We retrospectively reviewed bloodstream infections (BSI) in pediatric recipients of solid organ transplants over a 14‐year period. Overall BSI rates were significant but decreased over time. Risk factors for BSI were identified which may help identify interventions which further decrease rates.
Mario M. Landa, Ayelet Rosenthal, Caitlin Naureckas Li, Mehreen Arshad, Sameer Patel, Larry Kociolek, Alyah Barnes, Stella Karuri, William J. Muller   +8 more
wiley   +1 more source

pneumonia in a healthy immunocompetent patient: A case report and literature review

SAGE Open Medical Case Reports
Pneumocystis jirovecii pneumonia, typically an opportunistic infection, is commonly associated with risk factors such as low CD4+ lymphocyte count, underlying malignancies, organ transplantation, or immunosuppressive medications.
Houda Rouis, Chirine Moussa, Yoldez Houcine, Ines Zendah, Hamida Kwas, Habib Ghedira, Sonia Maâlej   +6 more
doaj   +1 more source