Results 61 to 70 of about 362,795 (239)

Promising Prodiginins Biological Activities

Chemistry &Biodiversity, EarlyView.
ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto, Melisa E. Gantner, Boris E. Rodenak‐Kladniew, Santiago Rodriguez, María L. Cuestas, Alan Talevi, Guillermo R. Castro   +6 more
wiley   +1 more source

Taking the challenge: A protocolized approach to optimize Pneumocystis pneumonia prophylaxis in renal transplant recipients

American Journal of Transplantation, 2018
While trimethoprim‐sulfamethoxazole is considered first‐line therapy for Pneumocystis pneumonia prevention in renal transplant recipients, reported adverse drug reactions may limit use and increase reliance on costly and less effective alternatives ...
K. Urbancic, F. Ierino, E. Phillips, P. F. Mount, A. Mahony, J. Trubiano   +5 more
semanticscholar   +1 more source

Pneumocystis Pneumonia During Medicamentous Treatment of Cushing’s Syndrome – A Description of Two Cases

Acta Medica, 2011
Only a few cases of pneumocystis pneumonia (PCP) in Cushing’s syndrome have been published in the literature so far. In the majority of these patients, the pneumonia occurred after reduction of the hypercortisolism with medicamentous treatment. We report
Filip Gabalec, Alžběta Zavřelová, Eduard Havel, Jaroslav Cerman, jr., Jakub Radocha, Ioannis Svilias, Jan Čáp   +6 more
doaj   +1 more source

Virtual Screening of Phytochemicals to Novel Target (HAT) Rtt109 in Pneumocystis Jirovecii using Bioinformatics Tools [PDF]

Journal of Clinical and Diagnostic Research, 2016
Introduction: Pneumocystis jirovecii is a fungus that causes Pneumocystis pneumonia in HIV and other immunosuppressed patients. Treatment of Pneumocystis pneumonia with the currently available antifungals is challenging and associated with ...
Ramya Sugumar, Abhinand Ponneri Adithavarman, Anusha Dakshinamoorthi, Darling Chellathai David, Padmavathi Kannan Ragunath   +4 more
doaj   +1 more source

A case of idiosyncratic drug‐induced agranulocytosis because of sulbactam/ampicillin

Journal of General and Family Medicine, EarlyView.
We report a case of agranulocytosis caused by sulbactam/ampicillin. During antimicrobial therapy, close monitoring of total white blood cell counts is essential. Abstract Idiosyncratic drug‐induced agranulocytosis is a rare but life‐threatening condition that requires immediate medical intervention.
Kazuya Toda, Kaku Kuroda, Moe Kuroda, Kota Kawai, Yukihiro Sato   +4 more
wiley   +1 more source

ECIL guidelines for the diagnosis of Pneumocystis jirovecii pneumonia in patients with haematological malignancies and stem cell transplant recipients.

Journal of Antimicrobial Chemotherapy, 2016
The Fifth European Conference on Infections in Leukaemia (ECIL-5) convened a meeting to establish evidence-based recommendations for using tests to diagnose Pneumocystis jirovecii pneumonia (PCP) in adult patients with haematological malignancies ...
A. Alanio, P. Hauser, K. Lagrou, W. Melchers, J. Helweg-Larsen, O. Matos, S. Cesaro, G. Maschmeyer, H. Einsele, J. Donnelly, C. Cordonnier, J. Maertens, S. Bretagne   +12 more
semanticscholar   +1 more source

CD4+ T-cell independent secondary immune responses to Pneumocystis pneumonia

Frontiers in Immunology, 2016
Pneumocystis pneumonia is a major cause of morbidity and mortality among immunocompromised patients, especially in the context of HIV/AIDS. In the murine model of Pneumocystis pneumonia, CD4+ T-cells are required for clearance of a primary infection of ...
Nicholas M de la Rua, Derrick Richard Samuelson, Tysheena P Charles, David Allen Welsh, Judd E. Shellito   +4 more
doaj   +1 more source

Utility of BioFire FilmArray Pneumonia Panel Plus in a High‐Risk Cohort: Children Post Allogeneic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pulmonary complications due to infection contribute significantly to post‐haematopoietic stem cell transplant (HCT) morbidity and mortality. Standard microbiological investigations, when performed on bronchoalveolar lavage (BAL) fluid, can take days to weeks to confirm a diagnosis.
Hannah Walker, Theresa Cole, Liam Gubbels, Helen Pham, Melanie Neeland, Diane Hanna, Vanessa Clifford, Shivanthan Shanthikumar, Gabrielle M. Haeusler   +8 more
wiley   +1 more source

Not COVID-19, Don’t Overlook Pneumocystis in Patients on Gefitinib!

Current Oncology, 2021
An 82-year-old woman treated for advanced lung cancer with gefitinb was admitted to the emergency unit complaining of dyspnea. Chest computed tomography found abnormalities classified as possible diffuse COVID-19 pneumonia.
Jérémy Barben, Valérie Quipourt, Jérémie Vovelle, Alain Putot, Patrick Manckoundia   +4 more
doaj   +1 more source

Systemic Biologics Have Similar Safety to Vedolizumab in Inflammatory Bowel Disease Patients Following Liver Transplantation

Alimentary Pharmacology &Therapeutics, EarlyView.
In liver transplant recipients with coexistent inflammatory bowel disease, incidence of infectious events observed between those exposed to ‘gut‐specific’ and ‘systemic’ biologics were similar. Biologic choice should not be influenced by concerns regarding their co‐prescription with transplant immunosuppression.
Simone Chin, Danny Con, Patrick Hilley, Crispin Corte, Ken Liu, Adam Testro, Peter De Cruz, Matthew C. Choy, Ashish Srinivasan   +8 more
wiley   +1 more source