Results 61 to 70 of about 1,206 (76)

Clinical and translational research in Pneumocystis and Pneumocystis pneumonia*

Parasite, 2011
Pneumocystis pneumonia (PcP) remains a significant cause of morbidity and mortality in immunocompromised persons, especially those with human immunodeficiency virus (HIV) infection.
Huang L.
doaj   +1 more source

Late diagnosis of HIV among Ukrainian refugees in the Czech Republic: A retrospective, observational study

HIV Medicine, Volume 26, Issue 6, Page 888-898, June 2025.
Abstract Objectives This retrospective, observational, non‐interventional study describes the demographics, characteristics, immunological and virological status, coinfections, healthcare unit of HIV diagnosis and follow‐up status of Ukrainian refugees with newly diagnosed HIV in the Czech Republic, with a special focus on those with a late HIV ...
Zofia Bartovská, Ricardo Massmann, David Jilich, Tomáš Groh, Lukáš Fleischhans, Milan Zlámal, Radek Svačinka, David Vydrář, Dalibor Sedláček, Miroslav Kubiska, Jaroslav Kapla, Lucie Nepovímová, Daniela Bartková, Lenka Olbrechtová, Zdeňka Jerhotová, Eva Novotná, Jakub Wnuk, Vratislav Němeček, Pavel Dlouhý, Štěpán Cimrman, Marek Malý   +20 more
wiley   +1 more source

Microarray studies on effects of Pneumocystis carinii infection on global gene expression in alveolar macrophages

BMC Microbiology, 2010
Background Pneumocystis pneumonia is a common opportunistic disease in AIDS patients. The alveolar macrophage is an important effector cell in the clearance of Pneumocystis organisms by phagocytosis.
Liao Chung-Ping, Xuei Xiaoling, Liu Yunlong, Cheng Bi-Hua, Lu Debao, Lasbury Mark E, Durant Pamela J, Lee Chao-Hung   +7 more
doaj   +1 more source

Connective tissue disease‐associated interstitial lung disease: an approach to treatment amidst an expanding evidence base

Internal Medicine Journal, Volume 55, Issue 6, Page 885-894, June 2025.
ABSTRACT Connective tissue disease‐associated interstitial lung disease (CTD‐ILD) comprises a heterogenous group of conditions characterised by immune‐mediated fibro‐inflammatory pulmonary injury. Although the disease course is variable, CTD‐ILD can progress to respiratory failure and thus has a profound impact on morbidity and mortality.
Michael Hong, Elizabeth Veitch, Sandhya Limaye   +2 more
wiley   +1 more source

Impact of sulfonamide allergy label on clinical outcomes of acute cystitis: a retrospective matched cohort study

Internal Medicine Journal, Volume 55, Issue 6, Page 993-1000, June 2025.
Abstract Background Cystitis is a common infection in an otherwise healthy individual. Sulfonamide antibiotics are first‐line treatment options. Sulfonamide allergy label (SAL) is the second most common antibiotic allergy label in electronic health records, yet its impact on clinical outcomes in patients with cystitis is not well‐characterised.
Ray Moussa, Tyler Miluski, Gisoo Ghaffari, Taha Al‐Shaikhly   +3 more
wiley   +1 more source

Pneumocystis jirovecii colonization in chronic pulmonary disease

Parasite, 2011
Pneumocystis jirovecii causes pneumonia in immunosuppressed individuals. However, it has been reported the detection of low levels of Pneumocystis DNA in patients without signs and symptoms of pneumonia, which likely represents colonization.
Gutiérrez S., Respaldiza N., Campano E., Martínez-Risquez M.T., Calderón E.J., De La Horra C.   +5 more
doaj   +1 more source

Efficacy and Safety of Combining r‐ATG With PTCy for GvHD Prophylaxis in Haploidentical HSC Transplantation for Malignancies—A Systematic Review

Journal of Cellular and Molecular Medicine, Volume 29, Issue 11, June 2025.
ABSTRACT Allogeneic haematopoietic stem cell transplantation (HSCT) for haematological malignancies can cause acute and chronic graft‐versus‐host disease (GvHD), impacting graft success and mortality. Rabbit anti‐thymocyte globulin (r‐ATG) or post‐transplant cyclophosphamide (PTCy) is effective in reducing GvHD in haploidentical‐HSCT.
Joseph M. John, Uday Kulkarni, Dinesh Pendharkar, Sachin Jadhav   +3 more
wiley   +1 more source

Development and Validation of a Pneumocystis jirovecii Real-time Polymerase Chain Reaction Assay for Diagnosis of Pneumocystis Pneumonia

Canadian Journal of Infectious Diseases and Medical Microbiology, 2015
BACKGROUND: Pneumocystis jirovecii (PJ), a pathogenic fungus, causes severe interstitial Pneumocystis pneumonia (PCP) among immunocompromised patients. A laboratory-developed real-time polyermase chain reaction (PCR) assay was validated for PJ detection ...
Deirdre L Church, Anshula Ambasta, Amanda Wilmer, Holly Williscroft, Gordon Ritchie, Dylan R Pillai, Sylvie Champagne, Daniel G Gregson   +7 more
doaj   +1 more source

Transcriptomic and Proteomic Approaches to Finding Novel Diagnostic and Immunogenic Candidates in Pneumocystis

mSphere, 2019
Pneumocystis pneumonia is the most common serious opportunistic infection in patients with HIV/AIDS. Furthermore, Pneumocystis pneumonia is a feared complication of the immunosuppressive drug regimens used to treat autoimmunity, malignancy, and ...
Taylor Eddens, Waleed Elsegeiny, David Ricks, Meagan Goodwin, William T. Horne, Mingquan Zheng, Jay K. Kolls   +6 more
doaj   +1 more source

Coexistência de infeções oportunistas pulmonares num doente com infeção por vírus da imunodeficiência humana e uma forma persistente de pneumonia por Pneumocystis jirovecii: caso clínico

Revista Portuguesa de Pneumologia, 2013
Resumo: Como é sabido, nos doentes com infeção por vírus da imunodeficiência humana (VIH) existe um alto risco de ocorrência de infeções oportunistas (IO), tais como as infeções por Pneumocystis jirovecii, um agente patogénico com distribuição mundial ...
D. Ponces Bento, F. Esteves, O. Matos, A.C. Miranda, F. Ventura, C. Araújo, K. Mansinho   +6 more
doaj