Results 81 to 90 of about 374,956 (253)

Point‐of‐Care Testing by Multiplex‐PCR in Different Compartments in Suspected Lower Respiratory Tract Infection After Lung Transplantation—Results of a Prospective Study

Transplant Infectious Disease, EarlyView.
Use of POCtmPCR with noninvasive samples (NPS and sputum) in LTx recipients with viral LRTI are a viable alternative to invasive BAL sampling, ABSTRACT Background Respiratory tract infections (RTIs) are a leading cause of morbidity and mortality following lung transplantation (LTx).
Susanne Simon, Merle Sophie Kaiser, Marcus Bachmann, Gérard Krause, Jens Gottlieb   +4 more
wiley   +1 more source

Molecular Respiratory Pathogen Panels in Lung Transplantation

Transplant Infectious Disease, EarlyView.
ABSTRACT Molecular respiratory pathogen panels are an innovative tool for the rapid detection of respiratory pathogens and antimicrobial resistance genes, offering the potential to improve diagnostic accuracy and guide timely antimicrobial therapy.
Andrea Lombardi
wiley   +1 more source

Pentamidine for Prophylaxis against Pneumocystis jirovecii Pneumonia in Pediatric Oncology Patients Receiving Immunosuppressive Chemotherapy

Antimicrobial Agents and Chemotherapy, 2018
Pneumocystis jirovecii pneumonia is a life-threatening opportunistic infection in children receiving immunosuppressive chemotherapy. Without prophylaxis, up to 25% of pediatric oncology patients receiving chemotherapy will develop Pneumocystis jirovecii ...
Melissa Quinn, J. Fannin, Joseph Sciasci, Allison W Bragg, Patrick K. Campbell, D. Carias, K. Crews, David Gregornik, S. Jeha, Gabriela M. Maron, J. Pauley, Hope D Swanson, J. Wolf, William L Greene   +13 more
semanticscholar   +1 more source

Stewardship of Molecular Diagnostics in Transplant Viral Infections

Transplant Infectious Disease, EarlyView.
ABSTRACT The transplant environment requires special considerations when testing for viral infections as immunosuppression results in atypical infection profiles. Microbes otherwise considered commensals or causing mild disease can lead to severe infections in transplant environments. Therefore, guidelines tend to recommend broader microbial testing in
Scott Sugden, David Reynoso, Reema Mathew, Michael Loeffelholz   +3 more
wiley   +1 more source

Immune responses of different hosts to Pneumocystis infection

European Respiratory Review
Pneumocystis pneumonia constitutes a critical life-threatening opportunistic infection, where the host's immune response plays a central role in its pathogenesis.
Jun Li, Xiangdong Mu, Haichao Li, Xinmin Liu   +3 more
doaj   +1 more source

Low uptake of antiretroviral therapy after admission with human immunodeficiency virus and tuberculosis in KwaZulu-Natal, South Africa. [PDF]

, 2010
A prospective cohort study was conducted among human immunodeficiency virus (HIV) infected in-patients with tuberculosis (TB) or other opportunistic infections (OIs) in South Africa to estimate subsequent antiretroviral therapy (ART) uptake and ...
Kappagoda, S, Kuritzkes, D R, Maphasa, K T M, Murphy, R A, Smeaton, L, Sunpath, H, Taha, B   +6 more
core   +1 more source

Regional and temporal changes in AIDS in Europe before HAART [PDF]

, 2002
In a prospective observational study 4485 patients from 46 clinical centres in 17 European countries were followed between April 1994 and November 1996.
Ben-Ishai, Z, Blaxhult, A, Colebunders, R, EuroSIDA Study Grp, E, Fatkenheuer, G, Fox, Z, Francioli, P, Kirk, O, Parkin, JM, Phillips, AN, Vanhems, P   +10 more
core   +2 more sources

Taking the challenge: A protocolized approach to optimize Pneumocystis pneumonia prophylaxis in renal transplant recipients

American Journal of Transplantation, 2018
While trimethoprim‐sulfamethoxazole is considered first‐line therapy for Pneumocystis pneumonia prevention in renal transplant recipients, reported adverse drug reactions may limit use and increase reliance on costly and less effective alternatives ...
K. Urbancic, F. Ierino, E. Phillips, P. F. Mount, A. Mahony, J. Trubiano   +5 more
semanticscholar   +1 more source

The Role of Belatacept‐Use and Senescence on Infectious and Mortality Complications After Kidney Transplantation

Transplant Infectious Disease, EarlyView.
ABSTRACT Introduction Studies evaluating the incidence of infections after belatacept as a substitute for calcineurin inhibitors (CNI) or antimetabolite in kidney transplant (KT) yielded conflicting results. We compared infectious outcomes after belatacept‐use to no belatacept‐use in KT recipients.
Hareesh Singam, Abdinoor Abdi, Wyatt Tarter, Ben Langworthy, Adam Bregman, Karam M. Obeid   +5 more
wiley   +1 more source

Update on the diagnosis and treatment of pneumonia

Therapeutic Advances in Respiratory Disease, 2011
Pneumocystis is an opportunistic fungal pathogen that causes an often-lethal pneumonia in immunocompromised hosts. Although the organism was discovered in the early 1900s, the first cases of Pneumocystis pneumonia in humans were initially recognized in ...
Eva M. Carmona, Andrew H. Limper
doaj   +1 more source