Results 131 to 140 of about 294,445 (234)

Practical Applications of Secondary/Extractive Electrospray Ionization (SESI): A Versatile Tool for Real‐Time Chemical Analysis

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT In the 1980s, researchers discovered the remarkable ability of electrospray plumes to effectively ionize gas‐phase molecules via secondary ionization. Around 20 years later—coinciding with the ambient mass spectrometry revolution—secondary electrospray ionization (SESI) and extractive electrospray ionization (EESI) coupled to mass spectrometry
Xin Luo   +5 more
wiley   +1 more source

Global, Regional, National, and Local Burden of COVID‐19 With Inequality Analysis Across 920 Locations, 2020–2021

open access: yesMed Research, EarlyView.
This study presents the first standardized assessment of the direct health burden of COVID‐19 across 920 locations worldwide during 2020 and 2021, covering five geographic levels: global, international regional, national, subnational, and local. Six key health measures, including incidence, prevalence, mortality, disability‐adjusted life years (DALYs),
Dan Shan   +41 more
wiley   +1 more source

Tracheostomy Outcomes in Children With Bronchopulmonary Dysplasia

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To quantify the tracheostomy‐related morbidity and mortality, readmissions, and airway interventions in tracheostomy‐dependent children with bronchopulmonary dysplasia (BPD). Study Design Retrospective chart review. Setting Tertiary care children's hospital.
Ada Cleary Sher   +10 more
wiley   +1 more source

Clinical characteristics and risk factors of severe bocavirus‐positive pneumonia in children and a literature review

open access: yesPediatric Discovery, EarlyView.
The study explored the clinical characteristics and risk factors of HBoV‐positive severe pneumonia in children. These findings indicate that HBoV can be identified in respiratory samples from children with severe pneumonia, denoting its role as a viral pathogen in hospitalized children with this condition.
Jing Liao   +6 more
wiley   +1 more source

Introduction to the database “efficacy of different treatment modalities for lower respiratory tract infections in children”

open access: yesPediatric Discovery, EarlyView.
This article introduces a national, multicenter, prospective, non‐interventional, observational registry study, which established a comprehensive and sustainable database of lower respiratory tract infection in children. This database will help improve the scientific research efficiency of clinicians and facilitate the exploration of underlying ...
Yu Deng   +40 more
wiley   +1 more source

Microbiota diversity and differences in the respiratory tract of children with pneumonia

open access: yesPediatric Investigation, EarlyView.
Differences in microbial communities in the upper and lower respiratory tract in patients with pneumonia were investigated in this study by sequencing the 16S rRNA genes in pharyngeal swabs and alveolar lavage fluid. Forty‐three subjects were enrolled in the study, and one upper and one lower respiratory tract sample were collected from each subject ...
Dandan Ge   +4 more
wiley   +1 more source

Guideline for the diagnosis, treatment, and prevention of respiratory syncytial virus infection in children in China

open access: yesPediatric Investigation, EarlyView.
ABSTRACT Respiratory syncytial virus (RSV) is one of the most common respiratory pathogens in children under 5 years of age worldwide and it seriously threatens children's health. In recent years, great progress has been made in the field of RSV‐related diseases.
Committee of Pediatrics   +16 more
wiley   +1 more source

Nanoparticle‐Based Tetracycline Delivery Systems: Advancing Therapeutic Effectiveness and Tackling Antibiotic Resistance

open access: yesParticle &Particle Systems Characterization, EarlyView.
This review explores improved tetracycline (TCN) delivery via polymer‐based nanocarriers to enhance solubility, stability, and targeted release. It also covers stimuli‐responsive systems, triggered by pH, enzymes, or reactive oxygen species (ROS), and co‐delivery approaches that increase therapeutic efficacy in cancer and inflammatory diseases ...
Mahsa Molaei Nasr   +5 more
wiley   +1 more source

Efficacy and safety of anifrolumab across organ domains of systemic lupus erythematosus: A systematic review and meta‐analysis

open access: yesRheumatology &Autoimmunity, EarlyView.
A systematic review and meta‐analysis were conducted to review all clinical trial results of anifrolumab for treating systemic lupus erythematosus. Fourteen studies were included comprising 1322 patients and five studies were meta‐analyzed. It was found that anifrolumab 300 mg IV led to clinical improvement across composite lupus scores, cutaneous ...
Yomna W. Mahmoud   +11 more
wiley   +1 more source

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