Results 131 to 140 of about 765,146 (313)

The pneumonia severity index predicts time to clinical stability in patients with community-acquired pneumonia [PDF]

, 2006
SETTING: A total of 33 hospitals in 13 countries in North America, Europe, Africa, Asia and Latin America. OBJECTIVE: To investigate the relationship between the pneumonia severity index (PSI) and the time to clinical stability from intravenous to oral ...
A. LaJoie, J. Roig, J. Ramirez, J. Rello, P. Rossi, Community Acquired Pneumonia Organization, E. Rodriguez, P. Fernandez, T. Marrie, K. Weiss, G. Levy, F. Blasi, C. Luna, C. Feldman, J. Porras, F. Arnold, F. Arteta   +16 more
core  

Pneumococcal serotypes and risk factors in adult community-acquired pneumonia 2018–20; a multicentre UK cohort study [PDF]

Background: Higher-valency pneumococcal vaccines are anticipated. We aimed to describe serotype distribution and risk factors for vaccine-serotype community-acquired pneumonia (CAP) in the two years pre-SARS-CoV-2 pandemic.
Lawrence, H, Eletu, S, Fry, NK, Lim, Wei Shen, French, N, Litt, David, French, Neil, Litt, D, Butler, J, Hill, Adam T., McKeever, Tricia M., Edwards-Pritchard, Rochelle C., Eletu, Seyi, Sheppard, Carmen L., Pick, Harry, Ashton, Deborah, Edwards-Pritchard, RC, Baskaran, V, Lansbury, Louise, Baskaran, Vadsala, Lim, WS, Hill, AT, Ladhani, S, Butler, Jo, Ashton, D, Aston, S, Fry, Norman K., Daniel, P, Lawrence, Hannah, Sheppard, CL, Lansbury, L, Trotter, C, Pick, H, Rodrigo, C, Rodrigo, Chamira, Trotter, Caroline, Bewick, T, Bendall, Lesley, Bewick, Thomas, McKeever, TM, Aston, Stephen, Daniel, Priya, Bendall, L, Ladhani, Shamez   +43 more
core   +2 more sources

De Novo 2.2 Mb 19q13.42–q13.43 Microdeletion Encompassing U2AF2: Support for a Haploinsufficiency Model

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT U2 small nuclear RNA auxiliary factor 2 (U2AF2) is an essential pre‐mRNA splicing factor involved in the early stages of pre‐mRNA splicing. To date, multiple individuals have been reported with predominantly heterozygous missense variants presenting intellectual disability, speech and motor delays, seizures, hypotonia, and thin or hypoplastic ...
Amanda Toledo, Sarah Araji, Weimin Bi, Seema R. Lalani   +3 more
wiley   +1 more source

Structural and Functional Siderophore Remodeling by Enzymatic Delipidation

Angewandte Chemie, EarlyView.
A surprising functional switch in bacterial siderophores was discovered through genome mining and the analysis of environmental and pathogenic Pandoraea species. Pandorachelin B, a lipocyclopeptide that promotes swarming motility, is cleaved by a specialized acylase, yielding a ring‐contracted, homodetic cyclopeptide, pandorachelin A, which exhibits ...
Elena Herzog, Keishi Ishida, Evelyn M. Molloy, Ron Hermenau, Kirstin Scherlach, Christian Hertweck   +5 more
wiley   +2 more sources

Histidine Supplementation Stabilizes Hearing and Vision and Improves Growth in HARS1‐Related Autosomal Recessive Disorder Associated With Usher‐Like Symptoms

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Autosomal recessive HARS1‐related disorder (originally described as Usher syndrome type 3B) caused by a homozygous Y454S variant in the histidyl‐tRNA synthetase gene (HARS1) is characterized by progressive sensorineural hearing and vision loss and respiratory deterioration with risk for sudden death following febrile illnesses.
Victoria Mok Siu, Rosan Kenana, Rana Chakrabarti, Sarah D. P. Wilhelm, Joseph Andrews, Susan J. Leat, Christina Parker, Michael Miller, Leslie A. Nangle, Wendy McCaul, Ashfia Chowdhury, Natalie Hutchings, Ryan A. Adams, Lauren Guy, Mandy Rhody, Verena Juncal, Marisa I. Mendes, Desiree E. C. Smith, Gajja S. Salomons, Angelica A. Moresco, Daphne L. McCulloch, D. Holmes Morton, Ilka U. Heinemann, C. Anthony Rupar   +23 more
wiley   +1 more source

Animal models of polymicrobial pneumonia [PDF]

, 2015
Sami Hraiech,1,2 Laurent Papazian,1,2 Jean-Marc Rolain,1 Fabienne Bregeon1,3IHU Méditerranée Infection, URMITE CNRS IRD INSERM UMR 7278, Marseille, France; 2Réanimation – Détresses respiratoires et Infections Sév ...
Rolain JM, Hraiech S, Papazian L, Bregeon F   +3 more
core  

Herd protection induced by pneumococcal conjugate vaccine

The Lancet Global Health, 2014
Keith P Klugman
doaj   +1 more source

A vision and a milestone: 10 years of pneumonia

Pneumonia, 2023
Ger T Rijkers, Stephen I Pelton
doaj   +1 more source

Immune Modulatory Therapy for Severe Dengue Hemorrhagic Fever in a Patient With Mitochondrial Complex I Deficiency: A Case Report

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Dengue virus (DENV) poses a serious global health challenge, particularly in cases of dengue hemorrhagic fever (DHF). Patients with preexisting mitochondrial disorders may be at increased risk for complications due to the specific impact of DENV on mitochondrial‐dependent cellular processes and immune function.
Audra N. Iness, Ameya S. Walimbe, Emily R. Strouphauer, Michio Hirano, Alejandro D. Iglesias, Valentina Emmanuele, Caitlin C. Griffin, Sheldon L. Kaplan, William A. Gomes, Karen K. Moeller, Stephen F. Kralik, Fernando Scaglia   +11 more
wiley   +1 more source

Correction: Promoting the use of social networks in pneumonia

Pneumonia, 2023
Catia Cillóniz, Leith Greenslade, Cristina Dominedò, Carolina Garcia-Vidal   +3 more
doaj   +1 more source