Synthesis and characterization of PIL/pNIPAAm hybrid hydrogels
In this study, varying amounts of NIPAAm and an ionic liquid (IL), namely 1-vinyl-3-isopropylimidazolium bromide ([ViPrIm]+[Br]−), have been used to synthesize hybrid hydrogels by radical emulsion polymerization. Amounts of 70/30%, 50/50%, 30/70%, 15/85%
Pfensig Sylvia +5 more
doaj +3 more sources
This work aims to evaluate the cytocompatibility and hemocompatibility of thermo‐responsive polymers as potential drug carrier. Thermo‐responsive poly(N‐isopropyl acrylamide) (PNIPAAm) and poly(N‐isopropyl acrylamide)‐poly(l‐lactide)‐poly(N‐isopropyl acrylamide) (PNIPAAm‐PLLA‐PNIPAAm) triblock copolymer were synthesized by atom transfer radical ...
Su, Feng +4 more
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AbstractTwo sets of emulsion particles have been synthesized. In the first set, surfactant free emulsion was used to directly synthesize PS‐PNIPAAM copolymer particles. In the second set, polystyrene particles with an ATRP initiator shell were first synthesized and subsequently grafted with PNIPAAM brushes.
V. Mittal +3 more
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Construction and property characterization of PNIPAAm-grafted chitosan/sodium alginate composite Thermo-responsive hydrogel films [PDF]
A series of thermo-responsive PNIPAAm-CS/SA composite hydrogel films were synthesized via radical polymerization and ionic cross-linking. FTIR, XPS, and NMR confirmed the successful covalent grafting of PNIPAAm onto the chitosan (CS) backbone.
Xiaoxue Lu +5 more
doaj +2 more sources
Neste trabalho, a termossensibilidade dos hidrogéis do tipo semi-IPN baseados em rede de alginato-Ca2+com poli(N-isopropil acrilamida) (PNIPAAm) entrelaçado, com diferentes teores de alginato e de PNIPAAm, foi caracterizada por meio de medidas de grau de
Márcia R. de Moura +2 more
doaj +2 more sources
Resistência mecânica de hidrogéis termo-sensíveis constituídos de Alginato-Ca2+ / PNIPAAm, tipo Semi-IPN Mechanicals resistance of thermosensitive hydrogels consisting of alginate-Ca2+ / PNIPAAm, type Semi-IPN [PDF]
Thermosensitive hydrogels were synthesized using alginate-Ca2+ in association with a thermosensitive polymer, such as PNIPAAm. The mechanical properties of the hydrogels were determined measuring the maximum tension of deformation.
Gilsinei Marques Campese +5 more
doaj +3 more sources
Smart mesoporous silica nanoparticles for precision cancer therapy: Tumor targeting and stimuli‐responsive controlled release [PDF]
Smart mesoporous silica nanoparticles integrate tunable pore structures, molecular gates, targeting ligands, and stimuli‐responsive components to achieve controlled drug release for precision cancer therapy. This review highlights design principles, therapeutic applications, and future directions in immunotherapy, biodegradability, biosafety, and ...
Majdi Al‐Amili, Lei Lei, Zhu Jin
wiley +2 more sources
Understanding the Diffusion of Dextrans in ‘Click’ PNIPAAm Hydrogels
Arguably the most important property of a hydrogel is the ability to allow the diffusion of solutes through the crosslinked network. Studies of the diffusion in hydrogels are important for providing information on the rate and extent of the passage of the solute and on the details of the microstructure of the hydrogel.
Ooi, Huey Wen +3 more
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Molecular design of dynamically thermoresponsive biomaterials [PDF]
Dynamically thermoresponsive biomaterials, particularly those utilizing poly(N-isopropylacrylamide) (PNIPAAm), have attracted much attention in biomedical applications due to their reversible phase transition near body temperature.
Jun Kobayashi +2 more
doaj +2 more sources
Peptide–PNIPAAm conjugate based hydrogels: synthesis and characterisation
Thermo-responsive PNIPAAm rich hydrogels with controllable properties have been prepared by introducing small quantities of peptide-PNIPAAm bioconjugates where the peptide self-assembled into a β-sheet rich fibrillar network. This was achieved in a one pot synthesis using a thiol-modified peptide as the chain-transfer agent in the free radical ...
Maslovskis, Antons +3 more
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