Results 1 to 10 of about 704 (162)

Podocyturia: an earlier biomarker of cardiovascular outcomes [PDF]

Scientific Reports, 2022
Urinary podocin and nephrin mRNAs (podocyturia), as candidate biomarkers of endothelial/podocyte injury, were measured by quantitative PCR in Type II diabetics with normal albumin excretion rates (AER) at baseline, at 3–4 years, and at 7 years ...
Assaad A. Eid, Robert H. Habib, Omar Chehab, Nour Al Jalbout, Hani Tamim, Maha Makki, Martine El Bejjani, Joao Lima, Kamal F. Badr   +8 more
doaj   +6 more sources

SGLT2抑制剂对糖尿病肾病患者的影响:基于尿足细胞的初步研究 [PDF]

Journal of Diabetes, 2022
Background The aim of this study was to investigate the effects of sodium glucose cotransporter 2 inhibitors (SGLT2i) on the glomerulus through the evaluation of podocyturia in patients with diabetic kidney disease (DKD). Methods The study population was
Emre Durcan, Serbay Ozkan, Halil Ibrahim Saygi, Mevlut Tamer Dincer, Ozge Polat Korkmaz, Serdar Sahin, Cebrail Karaca, Cem Sulu, Alev Bakir, Hande Mefkure Ozkaya, Sinan Trabulus, Elif Guzel, Nurhan Seyahi, Mustafa Sait Gonen   +13 more
doaj   +3 more sources

Podocyturia an emerging biomarker for kidney injury [PDF]

BMC Nephrology
Podocyte injury is an established hallmark of kidney disease progression. Podocyte loss is a widely proven hypothesis to explain, in part, glomerular damage.
Charbel Hanna, Hady El Etry, Maroun Ibrahim, Lynn Khalife, Sola Aoun Bahous, Wissam H. Faour   +5 more
doaj   +4 more sources

Evaluation of urinary podocin and nephrin as markers of podocyturia in dogs with leishmaniosis [PDF]

Parasites & Vectors
Background Renal disease is the main cause of death in canine leishmaniosis. Detection of an active glomerular injury is important to identify early renal damage and to prevent the development of chronic kidney disease.
Valeria Pantaleo, Tommaso Furlanello, Erika Carli, Laura Ventura, Laia Solano-Gallego   +4 more
doaj   +4 more sources

Mechanisms of Podocyte Detachment, Podocyturia, and Risk of Progression of Glomerulopathies [PDF]

Kidney Diseases, 2020
Background: Glomerulopathies are the main cause of ESRD. Primary or secondary causes of glomerular diseases comprise more than 70% of cases that end up in renal replacement therapies.
Hernán Trimarchi
doaj   +5 more sources

Nephrin and podocin mRNA detection in urine sediment of dogs with chronic kidney disease: preliminary observations [PDF]

Journal of Veterinary Research, 2022
Dogs with chronic kidney disease (CKD) may have alterations in the glomerular filtration barrier, including podocyte loss. Detection of podocyte mRNA in urine could be useful for assessing podocyturia in dogs with kidney disease.
Souza Camilla de, Coelho Mariana, Antonelo Daniel Silva, Passarelli Danielle, Rochetti Arina Lázaro, Fukumasu Heidge, Leite-Dellova Deise Carla Almeida   +6 more
doaj   +2 more sources

Urinary Podocyte Loss is Associated With Treatment Response in Patients With Primary Nephrotic Syndrome [PDF]

Kidney International Reports
Introduction: The disease course of primary nephrotic syndrome (PNS) is highly variable, and is difficult to predict at onset. PNS is characterized by podocyte injury and loss.
Bartholomeus T. van den Berge, Jitske Jansen, Quinty Leusink, Sanne Kleuskens, Sharon Bootsman, Anne-Els van de Logt, Jack F.M. Wetzels, Bart Smeets, Rutger J. Maas   +8 more
doaj   +2 more sources

Chitosan nanoencapsulation of Turbinaria triquetra metabolites in the management of podocyturia in nephrotoxic rats [PDF]

Scientific Reports
Cisplatin is a chemotherapeutic drug, which exhibits undesirable side effects. Chitosan nanoparticles are promising for drug delivery. The aim of this study was to determine the effect of the brown alga Turbinaria triquetra ethyl acetate fraction and ...
Abdullah Abdel-Aal, Abdel-Aziz A. F., Zakaria El-khayat, Nadia Mohamed, Merit Rostom, Emad Tolba, Nihal Galal El-Din Shams El-Din, Walaa S. A. Mettwally, Abdelhamid Aly Hamdy   +8 more
doaj   +2 more sources

Pathogenesis and Molecular Mechanisms of Anderson-Fabry Disease and Possible New Molecular Addressed Therapeutic Strategies. [PDF]

Int J Mol Sci, 2021
Anderson–Fabry disease (AFD) is a rare disease with an incidenceof approxi-mately 1:117,000 male births. Lysosomal accumulation of globotriaosylceramide (Gb3) is the element characterizing Fabry disease due to a hereditary deficiency α-galactosidase A ...
Tuttolomondo A, Simonetta I, Riolo R, Todaro F, Di Chiara T, Miceli S, Pinto A.   +6 more
europepmc   +3 more sources

Renal Involvement in Preeclampsia: Similarities to VEGF Ablation Therapy [PDF]

Journal of Pregnancy, 2011
Glomerular VEGF expression is critical for the maintenance and function of an intact filtration barrier. Alterations in glomerular VEGF bioavailability result in endothelial as well as in podocyte damage.
Janina Müller-Deile, Mario Schiffer
doaj   +4 more sources