Results 11 to 20 of about 704 (162)

Podocyturia: A Clue for the Rational Use of Amiloride in Alport Renal Disease [PDF]

Case Reports in Nephrology, 2016
No specific or efficient treatment exists for Alport syndrome, an X-linked hereditary disease caused by mutations in collagen type IV, a crucial component of the glomerular basement membrane. Kidney failure is usually a major complication of the disease,
H. Trimarchi, R. Canzonieri, A. Muryan, A. Schiel, A. Araoz, M. Paulero, J. Andrews, T. Rengel, M. Forrester, F. Lombi, V. Pomeranz, R. Iriarte, E. Zotta   +12 more
doaj   +4 more sources

Detection of podocyturia in patients with lupus nephritis [PDF]

Jornal Brasileiro de Nefrologia, 2013
INTRODUCTION: The podocyturia has been detected in glomerular diseases, such as lupus nephritis (LN), in which proteinuria is an important manifestation, and its occurrence seems to be limited to the active phase of the disease.
Mansur, Juliana Busato, Mastroianni Kirsztajn, Gianna, Nishida, Sonia Kiyomi, Sabino, Amelia Rodrigues Pereira, Sass, Nelson, Teixeira, Vicente de Paulo Castro   +5 more
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Podocyturia in pediatric patients with Fabry disease

Nefrología (English Edition), 2019
Introduction: Fabry disease (FD) is a hereditary disorder caused by a deficiency of α-galactosidase A enzyme activity. The transmission of the disorder is linked to the X chromosome. Objectives: The objectives of the study were: 1.
Miguel Liern, Anabella Collazo, Maylin Valencia, Alejandro Fainboin, Lorena Isse, Cristian Costales-Collaguazo, Federico Ochoa, Graciela Vallejo, Elsa Zotta   +8 more
doaj   +3 more sources

In Acute IgA Nephropathy, Proteinuria and Creatinine Are in the Spot, but Podocyturia Operates in Silence: Any Place for Amiloride?

Case Reports in Nephrology, 2017
IgA nephropathy is the most frequent cause of primary glomerulonephritis, portends erratic patterns of clinical presentation, and lacks specific treatment. In general, it slowly progresses to end-stage renal disease.
H. Trimarchi, M. Paulero, R. Canzonieri, A. Schiel, A. Iotti, C. Costales-Collaguazo, A. Stern, M. Forrester, F. Lombi, V. Pomeranz, R. Iriarte, T. Rengel, I. Gonzalez-Hoyos, A. Muryan, E. Zotta   +14 more
doaj   +2 more sources

A Compendium of Urinary Biomarkers Indicative of Glomerular Podocytopathy [PDF]

Pathology Research International, Volume 2013, Issue 1, 2013., 2013
It is well known that glomerular podocyte injury and loss are present in numerous nephropathies and that the pathophysiologic consecution of disease hinges upon the fate of the podocyte.
Pichler Sekulic, Simona, Sekulic, Miroslav   +1 more
core   +3 more sources

Early detection of active glomerular lesions in dogs and cats using podocin [PDF]

Journal of Veterinary Research, 2019
In veterinary medicine, sensitive and specific markers of the early stages of renal failure still remain to be established. Podocytes could be a promising diagnostic tool in veterinary nephrology, especially in the differentiation of active pathological ...
Szczepankiewicz Barbara, Pasławska Urszula, Nowak Marcin, Bąchor Remigiusz, Czyżewska-Buczyńska Agnieszka, Pasławski Robert, Szewczuk Zbigniew   +6 more
doaj   +2 more sources

The role of podocytes dysfunction in chronic glomerulonephritis progression [PDF]

Терапевтический архив, 2018
In the review, the mechanisms of podocytes damage underlying the development of proteinuria and progression of glomerulosclerosis in chronic glomerulonephritis are discussed in detail. The results of experimental and clinical studies are presented. Under
N V Chebotareva, I N Bobkova, L V Lysenko   +2 more
doaj   +3 more sources

Copious Podocyturia without Proteinuria and with Normal Renal Function in a Young Adult with Fabry Disease

Case Reports in Nephrology, 2015
The time for starting a patient with Fabry disease on enzyme replacement therapy is still a matter of debate, particularly when no overt classical clinical signs or symptoms are present.
H. Trimarchi, R. Canzonieri, A. Muryan, A. Schiel, A. Araoz, M. Forrester, A. Karl, F. Lombi, J. Andrews, V. Pomeranz, T. Rengel, E. Zotta   +11 more
doaj   +2 more sources

Expression of uPAR in Urinary Podocytes of Patients with Fabry Disease

International Journal of Nephrology, 2017
Background. Despite enzyme replacement therapy, Fabry nephropathy still progresses. Podocyturia is an irreversible event that antedates proteinuria and leads to chronic renal failure.
Hernán Trimarchi, Romina Canzonieri, Amalia Schiel, Juan Politei, Cristian Costales-Collaguazo, Aníbal Stern, Matías Paulero, Tatiana Rengel, Lara Valiño-Rivas, Mariano Forrester, Fernando Lombi, Vanesa Pomeranz, Romina Iriarte, Alexis Muryan, Alberto Ortiz, María Dolores Sanchez-Niño, Elsa Zotta   +16 more
doaj   +2 more sources

Evaluation of podocin in urine in horses using qualitative and quantitative methods. [PDF]

PLoS ONE, 2020
No sensitive method for diagnosing early kidney dysfunction in horses has been identified so far. Many studies carried out in humans and small animals show that podocin can be useful to diagnose various kidney diseases, mainly affecting the glomeruli ...
Natalia Siwińska, Urszula Pasławska, Remigiusz Bąchor, Barbara Szczepankiewicz, Agnieszka Żak, Paulina Grocholska, Zbigniew Szewczuk   +6 more
doaj   +2 more sources