An update on the role of membrane and soluble endoglin in vascular homeostasis [PDF]
1p.Peer ...
Bernabéu, Carmelo
core
PODOCYTURIA mRNAs: EARLIER AND SUPERIOR PREDICTORS OF CARDIOVASCULAR OUTCOMES [PDF]
AbstractIncreased filtration of albumin, a result of injury to glomerular endothelial and epithelial cells (podocytes), leads to increased albumin excretion rate (AER) which defines “moderate albuminuria”, a predictor of cardiovascular events (CVD).
Eid, Assaad A. +4 more
openaire +1 more source
Long-term kidney transplant outcomes have reached mild improvements recently. Parietal epithelial cells (PECs) are progenitor cells located along the Bowman’s capsule that can be isolated in urine, and display the capability to replace podocytes, but in ...
Anna Manonelles +11 more
doaj +1 more source
Clinical and diagnostic aspects of Fabry disease management : a narrative review with a particular focus on Brazilian experts’ perspectives [PDF]
Research on the genetics, epidemiology, and clinical manifestations of Fabry disease (FD) has increased significantly in recent years. However, some relevant clinical questions still need to be answered to develop better approaches to patient management.
Andrade, Luis Gustavo Modelli de +7 more
core
Serum Nephrin Levels in Severe Preeclampsia: A Cross-Sectional Study : Kadar Nephrin Serum pada Preeklamsia Berat: Sebuah Studi Potong Lintang [PDF]
Objective: To determine differences in serum nephrin levels in severe preeclampsia compared to normal pregnancy and also its correlation with systolic and diastolic blood pressure and proteinuria.Methods: This study is an analytical observational with ...
Bayuaji, Hartanto +2 more
core +2 more sources
Fabry Nephropathy: An Evidence-Based Narrative Review. [PDF]
Fabry disease (FD) is a rare, X-linked disorder caused by mutations in the GLA gene encoding the enzyme α-galactosidase A. Complete or partial deficiency in this enzyme leads to intracellular accumulation of globotriaosylceramide (Gb3) and other ...
Ambros, Joan Torras +16 more
core +5 more sources
Développement d’une méthode par spectrométrie de masse en tandem pour l’évaluation de la podocyturie chez des patients atteints de la maladie de Fabry et de prééclampsie [PDF]
Les podocytes sont des cellules viscérales hautement différenciées. Plusieurs protéines spécifiques, telles que la podocalyxine et la podocine, peuvent être analysées pour l'évaluation de la podocyturie. Cependant, la quantification précise des protéines
Martineau, Tristan
core +1 more source
#2493 Podocyturia: a novel biomarker of ageing
Abstract Background and Aims Urinary podocyte shedding (podocyturia) is a biomarker of glomerular injury in young and old individuals. Podocyturia is associated with diabetes and hypertension, and it is an early indicator of systemic cardiovascular disease. Importantly, podocyturia has also been noted
Houry Puzantian +6 more
openaire +1 more source
ON THE PATHOGENESIS OF PRE-ECLAMPSIA
Relevance. To date, there is no pathogenetic treatment for pre-eclampsia because the etiology and pathogenesis of this pathology are still poorly understood. Therefore, the analysis of possible causes and mechanisms of pre-eclampsia is an urgent problem,
B.M. Ventskovsky, V.G. Zhegulovych
doaj +1 more source
Mass spectrometry as a novel method for detection of podocyturia in pre-eclampsia [PDF]
Podocyturia, i.e. urinary loss of viable podocytes, may serve as a diagnostic tool for pre-eclampsia and as a marker of active renal disease. The current method to detect podocyturia is technically complex, lengthy and requires a high level of expertise for interpretation.
Vesna D, Garovic +7 more
openaire +2 more sources

