Results 271 to 280 of about 19,338 (290)

Expression of podoplanin and prognosis in oropharyngeal cancer

European Archives of Oto-Rhino-Laryngology, 2014
It has been shown that podoplanin expression is associated with carcinoma of the aerodigestive tract. Recent studies indicate that podoplanin may serve as a prognostic biomarker in oral carcinoma. In order to provide evidence on the role of podoplanin in oropharyngeal squamous cell carcinoma, we evaluated the prognostic impact of podoplanin in these ...
Simon F. Preuss, Jens Peter Klussmann, Guy D. Eslick, Robert Semrau, Inga Wedemeyer, Uta Drebber, Matthias Kreppel, Christian U. Huebbers, Inga M. C. Seuthe, Andreas Anagiotos   +9 more
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Expression of podoplanin in the mouse salivary glands

Archives of Oral Biology, 2008
Podoplanin is one of the most highly expressed lymphatic-specific genes. Here, we report the distribution of cells expressing podoplanin in mouse salivary glands.We immunohistochemically investigated the distribution of cells expressing podoplanin in mouse major salivary glands by laser-scanning microscopy.
Atsuko Sato, Minoru Hata, Hiroshi Kojima, Yoshihiko Sawa, Takeshi Ueki   +4 more
openaire   +3 more sources

Detection of Tiger Podoplanin Using the Anti-Cat Podoplanin Monoclonal Antibody PMab-52

Monoclonal Antibodies in Immunodiagnosis and Immunotherapy, 2018
Podoplanin (PDPN) is expressed in type I alveolar cells of lung but not in type II alveolar cells. PDPN is also known as a specific lymphatic endothelial cell marker because PDPN is not expressed in vascular endothelial cells. PDPNs of several animals have been characterized using specific anti-PDPN monoclonal antibodies (mAbs): PMab-1, PMab-2, PMab-32,
Yoshikazu Furusawa, Yoshimi Nakamura, Miyuki Yanaka, Hiroyuki Harada, Yukinari Kato, Takeshi Murata, Takuya Mizuno, Shunsuke Itai, Shunsuke Itai, Kayo Hisamatsu, Hideaki Tahara, Satoshi Ogasawara, Mika K. Kaneko, Takuro Nakamura, Yusuke Sakai, Masato Fukui, Shinji Yamada, Hiroaki Uchida, Saori Handa, Masato Sano   +19 more
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The role of podoplanin in cancer-associated thrombosis

Thrombosis Research, 2018
Venous thromboembolism (VTE) is a frequent and life-threatening complication in patients with cancer. The underlying mechanisms of cancer-associated VTE are still not completely understood. However, emerging studies indicate that the mechanisms differ across tumor types.
Cihan Ay, Pegah Mir Seyed Nazari, Ingrid Pabinger, Julia Riedl   +3 more
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The Roles of Podoplanin-Positive/Podoplanin-Negative Cells from Adipose-Derived Stem Cells in Lymphatic Regeneration

Plastic & Reconstructive Surgery, 2020
Background: Secondary lymphedema is a refractory disease, for which adipose-derived stem cells have shown some therapeutic potential. However, the mechanism of this action remains poorly understood. Methods: The authors identified podoplanin-expressing adipose-derived stem cells ...
Weigang Cao, Chunxiao Cui, Shengli Li, Bin Chen, Haibo Li, Lifei Guo, Zhaohua Jiang, Bolun Lu, Tingting Dai, Yiyu Sun   +9 more
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Cancer-associated fibroblasts promote venous thrombosis through podoplanin/CLEC-2 interaction in podoplanin-negative lung cancer mouse model.

Journal of Thrombosis and Haemostasis, 2023
Toshiaki Shirai, N. Tsukiji, Tomoyuki Sasaki, Saori Oishi, Ryohei Yokomori, Katsuhiro Takano, K. Suzuki-Inoue   +6 more
semanticscholar   +1 more source

Podoplanin: A Novel Diagnostic Immunohistochemical Marker

Advances in Anatomic Pathology, 2006
Podoplanin is a transmembrane mucoprotein recognized by the recently commercially available D2-40 monoclonal antibody. Recent investigations have shown that podoplanin is selectively expressed in lymphatic endothelium as well as lymphangiomas, Kaposi sarcomas, and in a subset of angiosarcomas with probable lymphatic differentiation. Podoplanin has also
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Lack of expression of podoplanin by microvenular hemangioma

Pathology - Research and Practice, 2008
Microvenular hemangioma (MH) is not a very common type of hemangioma, and it can occasionally be difficult to distinguish it from other benign vascular tumors and malignant tumors such as Kaposi's sarcoma. The latter has been shown to be negative for the marker D2-40. Nevertheless, the status of MH for D2-40 has not been established yet.
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Podoplanin, a novel marker for seminoma: A comparison study evaluating immunohistochemical expression of podoplanin and OCT3/4

Annals of Diagnostic Pathology, 2010
Podoplanin, a 38-kd membrane glycoprotein of podocytes, is the human homologue of mouse protein, aggrus, a 44-kd sialoglycoprotein; the latter has recently been reported in testicular seminomas but not in embryonal carcinomas, suggesting that it may be a specific marker for seminomas.
Romil Saxena, Muhammad T. Idrees, Thomas M. Ulbright, Liang Cheng, Sunil Badve   +4 more
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Establishment of a Monoclonal Antibody PMab-231 for Tiger Podoplanin.

Monoclonal antibodies in immunodiagnosis and immunotherapy, 2019
Podoplanin (PDPN), also known as T1alpha, has been used as a lung type I alveolar cell marker in the pathophysiological condition. Although we have established several monoclonal antibodies (mAbs) against mammalian PDPNs, mAbs against tiger PDPN (tigPDPN)
Yoshikazu Furusawa, M. Kaneko, Takuro Nakamura, Shunsuke Itai, M. Fukui, H. Harada, S. Yamada, Y. Kato   +7 more
semanticscholar   +1 more source